Results 31 to 40 of about 228,705 (316)
Journal of Cardiovascular Development and Disease, 2022 We report a pediatric patient with persistent left superior vena cava and a D-transposition of great arteries, which is an uncommon relation. It is crucial to know the anatomy of the persistent left superior vena cava and the dilated coronary sinus to ...
José Cruzalegui +5 more
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Free Radical Biology and Medicine, 2014 Mitochondria are essential to providing ATP, thereby satisfying the energy demand of the incessant electrical activity and contractile action of cardiac muscle. Emerging evidence indicates that mitochondrial dysfunction can adversely affect cardiac electrical functioning by impairing the intracellular ion homeostasis and membrane excitability through ...
Kai-Chien, Yang +2 more
openaire +3 more sources
LRP6 acts as a scaffold protein in cardiac gap junction assembly
Nature Communications, 2016 LRP6 is known for its role as a Wnt co-receptor essential for the canonical Wnt/β-catenin signaling. Here, Li et al. show that LRP6 exerts a Wnt-independent scaffold function and regulates connexin 43 gap junction formation and coupling of cardiomyocytes
Jun Li +21 more
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Modern pharmacological approach to arrhythmias in the 21st century
, 2023 Recent improvements in diagnosis techniques, increasing knowledge of changes in cardiac metabolism and the impact of electrolyte disturbance on the formation of arrhythmias, and the understandings of the pharmacological properties of both new and old ...
Katan, Karin
core
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundHeart failure is a complex syndrome characterized by cardiac contractile impairment with high mortality. Defective intracellular Ca2+ homeostasis is the central cause under this scenario and tightly links to ultrastructural rearrangements of ...
Lei Yao +11 more
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Frontiers in Pediatrics, 2021 Aim: To perform a comprehensive phenotype-genotype correlation of all rare variants in Triadin leading to malignant arrhythmias in pediatrics.Methods: Triadin knockout syndrome is a rare entity reported in pediatric population. This syndrome is caused by
Georgia Sarquella-Brugada +22 more
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, 2020 The main inherited cardiac arrhythmias are long QT syndrome, short QT syndrome, catecholaminergic polymorphic ventricular tachycardia and Brugada syndrome.
Schwartz, Peter J. +6 more
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Scientific Reports, 2018 To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, China.
Longbing Ren +8 more
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Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells
Frontiers in Physiology, 2023 Background: SGLT2i directly inhibit the cardiac sodium-hydrogen exchanger-1 (NHE1) in isolated ventricular cardiomyocytes (CMs). However, other studies with SGLT2i have yielded conflicting results.
Sha Chen +15 more
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FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source