Results 51 to 60 of about 228,705 (316)

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Brugada Syndrome and GPD1L: Definite Genotype-Phenotype Association?

Cardiogenetics
The GPD1L gene encodes a small cytoplasmic protein that is involved in the regulation of sodium currents. Alterations in this gene have been associated with Brugada syndrome.
Andrea Greco, Estefanía Martínez-Barrios, José Cruzalegui, Sergi Cesar, Fredy Chipa, Nuria Díez-Escuté, Patricia Cerralbo, Irene Zschaeck, Paula Loredo, Georgia Sarquella-Brugada, Oscar Campuzano   +10 more
doaj   +1 more source

Sex-Specific Aspects of Cardiac Electrophysiology and Arrhythmias

, 2023
This article provides a condensed but comprehensive summary of the latest knowledge of sex-specific aspects of arrhythmias. Starting with sex-based differences in electrophysiological properties of the heart, it further covers sex- and gender-differences
Hildegard Tanner, Babken Asatryan, Tanner, Hildegard, Mühl, Aline, Asatryan, Babken, Aline Mühl   +5 more
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Early and late post-operative arrhythmias after surgical myectomy: 45 years of follow-up [PDF]

, 2020
Aims: The aims of this study are to investigate the incidence and determinants of post-operative atrial arrhythmias, conduction disorders and mortality in hypertrophic obstructive cardiomyopathy (HOCM) patients undergoing transaortic myectomy.
Kik, C. (Charles), Lodder, Lucas, Taverne, Yannick J.H.J., Kharbanda, Rohit K., Kharbanda, R.K. (Rohit), Taverne, Y.J.H.J. (Yannick), Lodder, L. (Lucas), Jong, P.L. (Peter) de, Groot, N.M.S. (Natasja) de, de Groot, Natasja M.S., Bogers, Ad J.J.C.; id_orcid, Brundel, B.J.J.M. (Bianca), Bogers, Ad J.J.C., de Jong, Peter L., Bogers, A.J.J.C. (Ad), Kik, Charles, Brundel, Bianca J.J.M., Ragab, Ahmed A.Y., Ragab, A.A.Y. (Ahmed A.Y.)   +18 more
core   +1 more source

Weaving Intelligence: Thermally Drawn Multimaterial Fibers Toward AI‐Enabled Smart Textiles

Advanced Materials, EarlyView.
Thermally drawn multimaterial fibers are rapidly advancing as intelligent structural units for next‐generation smart textiles. Integrating multimaterial architectures with neuromorphic and spiking‐neural‐network principles enables fabrics that can sense, compute, and adapt autonomously.
Vuong Dinh Trung, Jiaxiang Yi, Hieu Nguyen‐Duc, Tien Nu Hoang Lo, Weili Zhao, Chaoqun Dong, Fabien Sorin, Baris Caglar, Lei Wei, Tung Nguyen‐Dang   +9 more
wiley   +1 more source

Left ventricular perforation by a chest tube: Case report and review of complications

Heart Vessels and Transplantation
Objective: The placement of a chest tube to resolve pleural effusion, pneumothorax or as a diagnostic method is a relatively common invasive procedure in the emergency room and hospitalization area, which is not inherent to presenting complications.
Ulises Rojel-Martinez, Pablo Andres Reatiga-Vega, Flor Mayranny Marquez-Maldonado, Alan Cordova-Fierro, Karla Bozada-Nolasco   +4 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Long-Term Cardiovascular Outcome in Children with MIS-C Linked to SARS-CoV-2 Infection—An Italian Multicenter Experience

Biology, 2022
MIS-C is a multisystem inflammatory syndrome that is characterized by multi-organ failure and cardiac involvement. The aim of this study was to describe the long-term cardiovascular outcome in a cohort of MIS-C pediatric patients, who were admitted to ...
Nicoletta Cantarutti, Virginia Battista, Nicola Stagnaro, Marianna Eleonora Labate, Marianna Cicenia, Marta Campisi, Valerio Vitali, Aurelio Secinaro, Andrea Campana, Gianluca Trocchio, Fabrizio Drago   +10 more
doaj   +1 more source