Results 51 to 60 of about 525,774 (351)

Investigation of the prevalence of Cognitive Impairment and its risk factors within the elderly population in Shanghai, China

Scientific Reports, 2018
To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, China.
Longbing Ren, Yongtao Zheng, Lezhou Wu, Yijun Gu, Yusheng He, Bo Jiang, Jie Zhang, Lijuan Zhang, Jue Li   +8 more
doaj   +1 more source

Arrhythmias and COVID-19

JACC Clinical Electrophysiology, 2020
Current understanding of the impact of coronavirus disease-2019 (COVID-19) on arrhythmias continues to evolve as new data emerge. Cardiac arrhythmias are more common in critically ill COVID-19 patients.
Parinita Dherange, Joshua P. Lang, P. Qian, Blake Oberfeld, W. Sauer, BRUCE A. Koplan, U. Tedrow   +6 more
semanticscholar   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Early detection of biochemically occult autonomous thyroid nodules [PDF]

, 2016
Objective: Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism, but may exist even in the presence of normal TSH.
Brusca, Nunzia, Capriello, Silvia, Cellini, Miriam, Centanni, Marco, Gargano, L., Salvatori, R., Santaguida, MARIA GIULIA, Virili, Camilla   +7 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

The ATLAS Randomised Clinical Trial: What do the Superiority Results Mean for Subcutaneous ICD Therapy and Sudden Cardiac Death Prevention as a Whole?

Arrhythmia & Electrophysiology Review, 2022
This review sets out the key evidence comparing subcutaneous ICDs (S-ICDs) and transvenous ICDs and uses it to empower clinical cardiologists and those who implant ICDs to make optimum patient selections for S-ICD use.
Roberto Rordorf
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Evaluación de la efectividad de la extracción de electrodos en pacientes con dispositivos electrónicos implantables: el estudio retrospectivo más grande en México

Gaceta Médica de México
Antecedentes: El uso de dispositivos electrónicos implantables cardíacos (CIED) ha aumentado en la última década, incrementando las complicaciones asociadas, siendo las infecciones la principal causa de extracción ...
Ignacio Moreno-Zenteno, Jose A. Manzanarez, Diego Neach-De la Vega, Adela Bazbaz, Carmen A. Sánchez-Contreras, Mario A. Ornelas-Casillas, Sylvia Salmun-Nehmad, Elías Terrazas-Cervantes, Manlio F. Márquez-Murillo, Moisés Levinstein-Jacinto, Jorge R. Gómez-Flores, Jose L. Morales-Velázquez, Santiago Nava   +12 more
doaj   +1 more source

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

A comparative study of early afterdepolarization-mediated fibrillation in two mathematical models for human ventricular cells [PDF]

, 2015
Early afterdepolarizations (EADs), which are abnormal oscillations of the membrane potential at the plateau phase of an action potential, are implicated in the development of cardiac arrhythmias like Torsade de Pointes.
Nayak, Alok Ranjan, Pandit, Rahul, Panfilov, Alexander, Vandersickel, Nele, Zimik, Soling   +4 more
core   +6 more sources