Results 51 to 60 of about 264,698 (302)

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

ECG-based evaluation of ventricular synchrony in left bundle branch area pacing through characterization of the activation sequence

Scientific Reports
Left bundle branch area pacing (LBBAP) overcomes ventricular dyssynchrony induced by conventional right ventricular pacing (RVP). Despite QRS duration (QRSd) being the standard ECG marker for biventricular synchrony, it lacks insights into the ...
Clara Sales-Belles, Ana Mincholé, Jorge Melero-Polo, Mercedes Cabrera-Ramos, Pablo Vadillo-Martín, Isabel Montilla-Padilla, Laura Sorinas-Villanueva, Inés Julián-García, Gualber Vitto Mayo-Carlos, José Ramón Ruiz-Arroyo, Esther Pueyo, Javier Ramos-Maqueda   +11 more
doaj   +1 more source

Evaluación de la efectividad de la extracción de electrodos en pacientes con dispositivos electrónicos implantables: el estudio retrospectivo más grande en México

Gaceta Médica de México
Antecedentes: El uso de dispositivos electrónicos implantables cardíacos (CIED) ha aumentado en la última década, incrementando las complicaciones asociadas, siendo las infecciones la principal causa de extracción ...
Ignacio Moreno-Zenteno, Jose A. Manzanarez, Diego Neach-De la Vega, Adela Bazbaz, Carmen A. Sánchez-Contreras, Mario A. Ornelas-Casillas, Sylvia Salmun-Nehmad, Elías Terrazas-Cervantes, Manlio F. Márquez-Murillo, Moisés Levinstein-Jacinto, Jorge R. Gómez-Flores, Jose L. Morales-Velázquez, Santiago Nava   +12 more
doaj   +1 more source

Protease XIV abolishes NHE inhibition by empagliflozin in cardiac cells

Frontiers in Physiology, 2023
Background: SGLT2i directly inhibit the cardiac sodium-hydrogen exchanger-1 (NHE1) in isolated ventricular cardiomyocytes (CMs). However, other studies with SGLT2i have yielded conflicting results.
Sha Chen, Sha Chen, Cees A. Schumacher, Cees A. Schumacher, Shirley C. M. Van Amersfoorth, Shirley C. M. Van Amersfoorth, Jan W. T. Fiolet, Jan W. T. Fiolet, Antonius Baartscheer, Antonius Baartscheer, Marieke W. Veldkamp, Marieke W. Veldkamp, Ruben Coronel, Ruben Coronel, Coert J. Zuurbier, Coert J. Zuurbier   +15 more
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

The ATLAS Randomised Clinical Trial: What do the Superiority Results Mean for Subcutaneous ICD Therapy and Sudden Cardiac Death Prevention as a Whole?

Arrhythmia & Electrophysiology Review, 2022
This review sets out the key evidence comparing subcutaneous ICDs (S-ICDs) and transvenous ICDs and uses it to empower clinical cardiologists and those who implant ICDs to make optimum patient selections for S-ICD use.
Roberto Rordorf
doaj   +1 more source

Rheumatoid Arthritis, Frailty, and Outcomes of Surgical Hospitalizations: A National Population‐Based Analysis

Arthritis Care &Research, EarlyView.
Objective Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective noncardiac surgery. Methods We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including adults
Ali Yazdanyar, Joshua Baker, Katherine D. Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Genetic basis and molecular biology of cardiac arrhythmias in cardiomyopathies. [PDF]

, 2020
Cardiac arrhythmias are common, often the first, and sometimes the life-threatening manifestations of hereditary cardiomyopathies. Pathogenic variants in several genes known to cause hereditary cardiac arrhythmias have also been identified in the ...
Asatryan, Babken, Marian, Ali J, Wehrens, Xander H T, Wehrens XHT, Marian AJ, Asatryan B   +5 more
core   +2 more sources

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High Body Mass Index

Arthritis Care &Research, EarlyView.
Objective High body mass index (BMI ≥ 27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck, J. Elyse Borgert, Hyeon Lee, Liubov Arbeeva, Yvonne M. Golightly, Richard F. Loeser, Leigh F. Callahan, Stephen P. Messier, Brian Pietrosimone, Amanda E. Nelson, James S. Marron   +10 more
wiley   +1 more source

Risk of arrhythmias following COVID-19 : nationwide self-controlled case series and matched cohort study

, 2023
Aims: COVID-19 increases the risk of cardiovascular disease, especially thrombotic complications. There is less knowledge on the risk of arrhythmias after COVID-19. In this study, we aimed to quantify the risk of arrhythmias following COVID-19.
Katsoularis, I, Jerndal, Hanna, Lindmark, K,, Jerndal, H, Fors Connolly, Anne-Marie, Kalucza, S, Fonseca Rodriguez, Osvaldo, Connolly, A-MF, Kalucza, Sebastian, Lindmark, Krister, Fonseca-Rodriguez, O, Katsoularis, Ioannis, Kalucza, Sebastian,, Fonseca Rodriguez, Osvaldo,, Jerndal, Hanna,, Lindmark, Krister,, Fors Connolly, Anne-Marie,, Katsoularis, Ioannis,   +17 more
core   +1 more source