Results 71 to 80 of about 382,024 (296)

A Beating‐Heart Procedure with Soft Robotic Guidance

Advanced Robotics Research, EarlyView.
Robot‐assisted pacemaker lead placement through the coronary sinus enabled cardiac pacing in multiple in vivo studies. When compared with conventional clinical tools, the robot reduced procedural time, duration of harmful radiation exposure, and the possibility of tissue damage.
Jacob Rogatinsky, Dominic Recco, Manisha Singh, Leonardo Zamora Yañez, Grace Matthews, Brian Ayers, Edward O’Leary, Ellen T. Roche, David Hoganson, Tommaso Ranzani   +9 more
wiley   +1 more source

Long-Term Cardiovascular Outcome in Children with MIS-C Linked to SARS-CoV-2 Infection—An Italian Multicenter Experience

Biology, 2022
MIS-C is a multisystem inflammatory syndrome that is characterized by multi-organ failure and cardiac involvement. The aim of this study was to describe the long-term cardiovascular outcome in a cohort of MIS-C pediatric patients, who were admitted to ...
Nicoletta Cantarutti, Virginia Battista, Nicola Stagnaro, Marianna Eleonora Labate, Marianna Cicenia, Marta Campisi, Valerio Vitali, Aurelio Secinaro, Andrea Campana, Gianluca Trocchio, Fabrizio Drago   +10 more
doaj   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

Radiosensitization of calreticulin‐overexpressing human glioma cell line by the polyphenolic acetate 7, 8‐diacetoxy‐4‐methylcoumarin

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background Calreticulin (CRT), an endoplasmic reticulum–resident protein generally overexpressed in cancer cells, is associated with radiation resistance. CRT shows higher transacetylase activity, as shown by us earlier, in the presence of the polyphenolic acetates (like 7, 8‐diacetoxy‐4‐methylcoumarin, DAMC) and modifies the activity of a ...
Amit Verma, Aastha Arora, Anant N Bhatt, Mohan B Arya, Ashok K Prasad, Virinder S Parmar, Bilikere S Dwarakanath   +6 more
wiley   +1 more source

Permanent junctional reciprocating tachycardia in a patient with an atypically located accessory pathway in the left lateral mitral annulus

Revista Portuguesa de Cardiologia, 2016
Permanent junctional reciprocating tachycardia (PJRT) is an uncommon form of atrioventricular reentrant tachycardia due to an accessory pathway characterized by slow and decremental retrograde conduction.
Moisés Rodríguez-Mañero, Xesús A. Fernández-López, Laila González-Melchor, Javier García-Seara, Jose Luis Martínez-Sande, José Ramón González-Juanatey   +5 more
doaj  

Brugada Syndrome and GPD1L: Definite Genotype-Phenotype Association?

Cardiogenetics
The GPD1L gene encodes a small cytoplasmic protein that is involved in the regulation of sodium currents. Alterations in this gene have been associated with Brugada syndrome.
Andrea Greco, Estefanía Martínez-Barrios, José Cruzalegui, Sergi Cesar, Fredy Chipa, Nuria Díez-Escuté, Patricia Cerralbo, Irene Zschaeck, Paula Loredo, Georgia Sarquella-Brugada, Oscar Campuzano   +10 more
doaj   +1 more source

A Heart Failure-Associated SCN5A Splice Variant Leads to a Reduction in Sodium Current Through Coupled-Gating With the Wild-Type Channel

Frontiers in Physiology, 2021
Nav1.5, encoded by the gene SCN5A, is the predominant voltage-gated sodium channel expressed in the heart. It initiates the cardiac action potential and thus is crucial for normal heart rhythm and function.
Yang Zheng, Yang Zheng, Xiaoping Wan, Dandan Yang, Angelina Ramirez-Navarro, Haiyan Liu, Ji-Dong Fu, Isabelle Deschênes   +7 more
doaj   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

Small RNA zippers lock miRNA molecules and block miRNA function in mammalian cells

Nature Communications, 2017
MicroRNAs regulate a wide range of biological processes and being able to inhibit their function could allow the development of therapeutic options.
Lingyu Meng, Cuicui Liu, Jinhui Lü, Qian Zhao, Shengqiong Deng, Guangxue Wang, Jing Qiao, Chuyi Zhang, Lixiao Zhen, Ying Lu, Wenshu Li, Yuzhen Zhang, Richard G. Pestell, Huiming Fan, Yi-Han Chen, Zhongmin Liu, Zuoren Yu   +16 more
doaj   +1 more source

Diagnostic potential of a circulating miRNA model associated with therapeutic effect in heart failure

Journal of Translational Medicine, 2022
Heart failure (HF), as the leading cause of death, is continuing to increase along with the aging of the general population all over the world. Identification of diagnostic biomarkers for early detection of HF is considered as the most effective way to ...
Lu Qian, Qian Zhao, Ping Yu, Jinhui Lü, Yuefan Guo, Xin Gong, Yuanyuan Ding, Shanshan Yu, Lieying Fan, Huimin Fan, Yuzhen Zhang, Zhongmin Liu, Hongzhuan Sheng, Zuoren Yu   +13 more
doaj   +1 more source