Results 81 to 90 of about 363,823 (338)

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]

open access: yes, 2009
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S.   +2 more
core  

Topological constraints on spiral wave dynamics in spherical geometries with inhomogeneous excitability [PDF]

open access: yes, 2004
We analyze the way topological constraints and inhomogeneity in the excitability influence the dynamics of spiral waves on spheres and punctured spheres of excitable media. We generalize the definition of an index such that it characterizes not only each
A. T. Winfree   +10 more
core   +1 more source

Reprogramming the Myocardial Infarction Conductive Microenvironment with Superconductive Ionic Patch for Cardiac Function Repair

open access: yesAdvanced Science, EarlyView.
A super‐conductive ionic patch reprograms the post‐infarction microenvironment by enabling stable ionic migration and electrical signal transmission within damaged myocardium. The patch rapidly adheres to cardiac tissue, enhances conduction velocity, suppresses excitation‐contraction decoupling, and promotes structural and functional cardiac repair in ...
Changyong Wang   +8 more
wiley   +1 more source

Local impedance and contact force guidance to predict successful cavotricuspid isthmus ablation with a zero-fluoroscopy approach

open access: yesFrontiers in Cardiovascular Medicine
IntroductionA new technology capable of monitoring local impedance (LI) and contact force (CF) has recently been developed. At the same time, there is growing concern regarding catheter ablation performed under fluoroscopy guidance, due to its harmful ...
Jorge Melero-Polo   +7 more
doaj   +1 more source

Effect of myocyte-fibroblast coupling on the onset of pathological dynamics in a model of ventricular tissue [PDF]

open access: yes, 2017
Managing lethal cardiac arrhythmias is one of the biggest challenges in modern cardiology, and hence it is very important to understand the factors underlying such arrhythmias.
Panfilov, Alexander   +2 more
core   +2 more sources

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou   +8 more
wiley   +1 more source

Antiarrhythmic therapy for narrow QRS supraventricular tachyarrhythmias in newborns and infants in the first year of life: Potent tools to be handled with care

open access: yesIndian Pacing and Electrophysiology Journal
Supraventricular tachyarrhythmias pose a significant challenge in neonates and infants, particularly within the first year of life, where prompt and effective management is crucial.
Giovanni Domenico Ciriello   +13 more
doaj   +1 more source

Fever Unmasked Brugada Syndrome in Pediatric Patient: A Case Report [PDF]

open access: yes, 2020
Introduction: Brugada syndrome is an arrhythmogenic disorder that is a known cause of sudden cardiac death. It is characterized by a pattern of ST segment elevation in the precordial leads on an electrocardiogram (EKG) due to a sodium channelopathy.Case ...
Brill, April   +2 more
core  

A comparative study of early afterdepolarization-mediated fibrillation in two mathematical models for human ventricular cells [PDF]

open access: yes, 2015
Early afterdepolarizations (EADs), which are abnormal oscillations of the membrane potential at the plateau phase of an action potential, are implicated in the development of cardiac arrhythmias like Torsade de Pointes.
Nayak, Alok Ranjan   +4 more
core   +3 more sources

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