Results 81 to 90 of about 347,894 (338)
Etiological diagnosis, prognostic significance and role of electrophysiological study in patients with Brugada ECG and syncope. [PDF]
, 2017 BACKGROUND: Syncope is considered a risk factor for life-threatening arrhythmias in Brugada patients. Distinguishing a benign syncope from one due to ventricular arrhythmias is often difficult, unless an ECG is recorded during the episode.
Anselmino, M +14 more
core +2 more sources
High‐Throughput MicroED for Probing Ion Channel Dynamics
Advanced Science, EarlyView.High‐throughput MicroED offers a new approach for visualizing ion channel dynamics. This approach reveals NaK’s sodium binding modes and NaK2CNG’s potassium‐induced selectivity filter dilation and gating. By capturing these distinct structures, this work challenges traditional models of ion channel permeation and selectivity. Abstract Ion channels play
Marc J Gallenito +4 more
wiley +1 more source
Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia [PDF]
, 2018 Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmogenic syndrome characterized by sudden death. There are several genetic forms of CPVT associated with mutations in genes encoding the cardiac ryanodine receptor (RyR2 ...
Belevych, Andriy E +12 more
core +1 more source
Advanced Science, EarlyView.Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng +9 more
wiley +1 more source
Neurogenic disturbances of cardiac rhythm [PDF]
, 2014 Arrhythmias are disturbances of electrical activation of the heart and are commonly encountered clinical conditions. Although typically associated with cardiac pathology, they have also been described in stroke and epilepsy.
Loh, Daniel, Pullicino, Patrick
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Endothelin and the ischaemic heart [PDF]
, 2005 Soon after its identification as a powerful vasoconstrictor peptide, endothelin (ET-1) was implicated as a detrimental agent involved in determining the outcome of myocardial ischaemia and reperfusion.
Kane, K.A., McCabe, C., Wainwright, C.L.
core +1 more source
Advanced Electronic Materials, EarlyView.This study presents an ECRAM‐based physical reservoir computing system for real‐time electrocardiogram arrhythmia detection. By optimizing electrolyte ionic conductivity and channel ionic diffusivity, it achieves including non‐linear dynamics, millisecond‐scale tunable retention, low‐power operation, and minimal variation.
Kyumin Lee +3 more
wiley +1 more source
Free Radical Biology and Medicine, 2014 Mitochondria are essential to providing ATP, thereby satisfying the energy demand of the incessant electrical activity and contractile action of cardiac muscle. Emerging evidence indicates that mitochondrial dysfunction can adversely affect cardiac electrical functioning by impairing the intracellular ion homeostasis and membrane excitability through ...
Marcelo G. Bonini +2 more
openaire +4 more sources
Electrocardiographic manifestation of cardiac repolarization dispersion [PDF]
, 2019 Alterations of repolarization heterogeneity in the heart have been established as anAlterations of repolarization heterogeneity in the heart have been established as ...
Sedova Ksenia
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