Results 91 to 100 of about 32,361 (211)

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence [PDF]

, 2016
Additional file 3: Figure S3. Regulation of genes of Arrhythmogenic right ventricular cardiomyopathy pathway during senescence induction in HFF strains Genes of the “Arrhythmogenic right ventricular cardiomyopathy” pathway which are significantly up ...
A Chicas, A Ciccia, A Iglesias-Ara, A Kaneda, A Leonardo Di, A Massoud, A Musio, A Ors, A Poehlmann, A Saadane, A Smogorzewska, A Ventura, A Zuryń, A Zuryń, AA Goodarzi, AB Parrish, AC Baege, AC Johansson, AJ Nakamura, AJT Millis, AM Havelka, AY Maslov, B Cen, B Pandit, B Zhivotovsky, BD Chang, Bernardes Jesus de, BP Kaistha, C Kenyon, C Michaloglou, C Morvan Le, C Rouault, C Sandhu, C Sidler, C Trapnell, CF Winter de, Christoph Kaether, CM Aliouat-Denis, D Bhaumik, D Coppola, D Lodygin, D Muthna, DA Alcorta, DH Lackner, DH Larsen, DJ Baker, DM Finucane, DN Shelton, DR Bentley, DR Wonsey, DW Chan, E Hara, E Natarajan, E Pazolli, EJ Gavin, ES Hwang, F Debacq-Chainiaux, F d’Adda di Fagagna, F Ling, F Rapaport, F Rodier, F Rodier, F Seyednasrollah, FA Mallette, G Thuret, GP Dimri, GP Dimri, GP Dimri, H Harada, H Takai, H Zalzali, HJ Kim, HJ Kim, I Androic, I Ben-Porath, I Ben-Porath, I Wierstra, IB Roninson, IK Yoon, IM Kim, IP Kovalchuk, J Bartkova, J Bunt, J Campisi, J Campisi, J Campisi, J Campisi, J Laoukili, J Manns, J Pawlowski, J Tomida, J Zhao, JC Acosta, JC Jeyapalan, JF Passos, JH Chen, JH Chen, JH Chin, JM Dhahbi, JM Yi, JP Carey, JP Coppé, JR Smith, JW Hofmann, JW Shay, K Itahana, K Johung, K Suzuki, K Voutetakis, KH Choi, KS Kim, L Gopinathan, L Hayflick, L Hirsch, L Jia, L Meng, L Zhang, M Blank, M Braig, M Collado, M Kronschnabl, M Narita, M Petric, M Purcell, M Serrano, MA Bonelli, Marco Groth, Matthias Platzer, MD Robinson, MI Love, MJ Smout, MK Ha, MK Kang, MT Paulsen, N Kikuchi, N Martin, N Ohtani, N Wajapeyee, NF Mathon, NG Berube, O Aksoy, O Toussaint, P Dekker, P Flicek, P Gupta, P Luo, P Sun, Peter Hemmerich, Q Gan, QF Wu, R Binet, R Mirzayans, R Mjelle, R Salama, RA Quadri, Reinhard Guthke, RJ Sabin, RT Abraham, S Anders, S Courtois-Cox, S Ferrando-Martinez, S Gonzalez, S Haupt, S Honda, S Hubackova, S Kim, S Lin, S Marthandan, S Marthandan, S Marthandan, S Marthandan, S Pollok, S Ressler, S Schäuble, S Sivakumar, S Vaughan, S Walter, Shiva Marthandan, SJ Robles, SP Linke, SP Mooijaart, SS Myatt, Steffen Priebe, Stephan Diekmann, T Chen, T Kaneko, T Kidokoro, T Kuilman, TC Kuilman, TV Kalin, U Herbig, Uwe Menzel, V Gire, VV Kalinichenko, W Cosme-Blanco, W Luo, W Wagner, W Xue, XW Cheng, Y Bai, Y Benjamini, Y Chien, Y Kong, Y Kotake, Y Ma, Y Nakayama, Y Takahashi, Y Tan, Y Zhang, YH Hsu, YJ Choi, YM Kim, Z Chen, Z Gong, Z Wang, Z Xie   +215 more
core   +5 more sources

Recurrent Syncope in a Young Man: What Lies Underneath?

Indian Journal of Clinical Cardiology
Arrhythmogenic right ventricular cardiomyopathy is an autosomal dominant genetic disease which leads to fatty replacement of the right ventricular myocardium, leading to the occurrence of ventricular arrhythmia.
Deepanjan Bhattacharya, Koyel Chakraborty, Ajay Gautam, Basudeb Bhattacharjee   +3 more
doaj   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Arrhythmogenic left ventricular cardiomyopathy

BJR|case reports, 2020
Arrhythmogenic ventricular cardiomyopathy (AVC) is a heritable heart muscle disorder characterized by fibrofatty infiltration of the myocardium. Intramyocardial fat deposition is considered arrhythmogenic and predisposes patients to life-threatening arrhythmias and sudden cardiac death.
Mirmomen, Seyedeh Mojdeh, Bradley, Andrew Jay, Arai, Andrew Ernest, Sirajuddin, Arlene   +3 more
openaire   +2 more sources

Haemodynamic‐energetic mechanism of sudden cardiac death in severe aortic stenosis: A modelling study

The Journal of Physiology, EarlyView.
Abstract figure legend A sudden decrease in total peripheral resistance (TPR), as observed during vasovagal syncope, leads to a reduction in aortic systolic pressure (AO pressure) and afterload. In healthy individuals, the consequent decrease in left ventricular systolic pressure (LV pressure) lowers stroke work and myocardial energy expenditure.
Martin Dvoulety, Michal Sitina
wiley   +1 more source

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Mestron, A Piovesan, AC Dirtu, AM Pereira, B Posch, BJ Maron, BPP Meij, BR Bond, C Paige, C-Y Liu, CJL Little, CR Lamb, David B. Church, David J. Connolly, DJ Connolly, F Fracassi, G Jacobs, G Lombardi, G Lombardi, J Dal, J Gilbert, JA Myers, JK Sangster, JM Fletcher, JR Payne, JT Lie, Kieran Borgeat, LJ Wilkie, Lois Wilkie, M Galderisi, M Lesser, M Maxie Grant, M Nishiki, M Rosca, M-LL Jaffrain-Rea, MD Kittleson, ME Peterson, ME Peterson, NJ Pereira, Norelene Harrington, NS Moise, NS Moise, O Kershaw, OM Dekkers, P Menaut, PR Fox, PR Fox, PR Fox, PR Fox, PR Fox, R Baldelli, R Gostelow, R Pivonello, RC Weichselbaum, S Brown, S Fazio, S Fazio, S Fazio, S Fieffe, S Murarka, S Niessen, SJM Niessen, SJM Niessen, SJM Niessen, SK Liu, SK Liu, Stijn J. M. Niessen, SV Keyte, T Wagner, T. Rosol, Vincenzo Lionetti, Virginia Luis Fuentes, WL McGuffin   +80 more
core   +2 more sources

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

The Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach, Laura Bevis, Cynthia Nwanna, Alexander M Zolotarev, Mahmoud Ehnesh, Semhar Biniam Misghina, Sayed Al‐Aidarous, Shohreh Honarbakhsh, Caroline H. Roney   +8 more
wiley   +1 more source

Functional Effects of the TMEM43 Ser358Leu Mutation in the Pathogenesis of Arrhythmogenic Right Ventricular Cardiomyopathy [PDF]

, 2012
Background: The Ser358Leu mutation in TMEM43, encoding an inner nuclear membrane protein, has been implicated in arrhythmogenic right ventricular cardiomyopathy (ARVC). The pathogenetic mechanisms of this mutation are poorly understood.
Ahmad, Ferhaan, McDonough, Barbara Anne, Rajkumar, Revathi, Seidman, Christine Edry, Sembrat, John C   +4 more
core   +5 more sources