Results 51 to 60 of about 14,748 (188)

Arrhythmogenic cardiomyopathy of the right ventricle. Predictive value of QT interval dispersion to assess arrhythmogenic risk and sudden death

Arquivos Brasileiros de Cardiologia, 2000
OBJECTIVE: To determine in arrhythmogenic right ventricular cardiomyopathy the value of QT interval dispersion for identifying the induction of sustained ventricular tachycardia in the electrophysiological study or the risk of sudden cardiac death ...
Márcio L. A. Fagundes, Ivan G. Maia, Fernando E. S. Cruz Fº, Paulo A. G. Alves, Silvia H. Boghossian, José Carlos Ribeiro, Roberto Sá   +6 more
doaj   +1 more source

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Natural Course of Electrocardiographic Features in Arrhythmogenic Right Ventricular Cardiomyopathy and Their Relation to Ventricular Arrhythmic Events

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Electrocardiographic abnormalities are common in arrhythmogenic right ventricular cardiomyopathy and are included in the 2010 Task Force Criteria. Their time course, however, remains uncertain.
Anneli Svensson, Henrik Kjaerulf Jensen, Machteld J. Boonstra, Marianne Tétreault‐Langlois, Pia Dahlberg, Henning Bundgaard, Alex Hørby Christensen, Rebecca T. Rylance, Jesper H. Svendsen, Julia Cadrin‐Tourigny, Anneline S. J. M. te Riele, Pyotr G. Platonov   +11 more
doaj   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, EarlyView.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Relationship Between Electrocardiographic Findings and Cardiac Magnetic Resonance Phenotypes in Arrhythmogenic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background The new designation of arrhythmogenic cardiomyopathy defines a broader spectrum of disease phenotypes, which include right dominant, biventricular, and left dominant variants. We evaluated the relationship between electrocardiographic findings
Manuel De Lazzari, Alessandro Zorzi, Alberto Cipriani, Angela Susana, Giulio Mastella, Alessandro Rizzo, Ilaria Rigato, Barbara Bauce, Benedetta Giorgi, Carmelo Lacognata, Sabino Iliceto, Domenico Corrado, Martina Perazzolo Marra   +12 more
doaj   +1 more source

Invasive Assessment of Right Ventricular Dysfunction Predicts Periprocedural Outcomes in Patients Undergoing Unplanned Ventricular Tachycardia Ablation

Journal of Cardiovascular Electrophysiology, EarlyView.
Displays bar graphs showing outcome rates stratified by clinical and hemodynamic variables. Asterisks (*) denote statistically significant differences (p ≤ 0.05). “NS” indicates non‐significant comparisons. Percentages are shown above each bar. The top panel corresponds to acute kidney injury (blue bars), and the bottom panel corresponds to acute ...
Tess Calcagno, Sai Prasad Ramachandran, V. Karthik, Mendpara Vaidehi, Andrew Cesmat, Joseph Sipko, Bryan Baranowski, Mandeep Bhargava, Thomas D. Callahan, Mina K. Chung, Thomas Dresing, Ayman A. Hussein, Mohamed Kanj, Arshneel Kochar, David O. Martin, Walid I. Saliba, Tyler L. Taigen, Niraj Varma, Koji Higuchi, Justin Z. Lee, Oussama M. Wazni, Andres Carmona Rubio, Pasquale Santangeli, Jakub Sroubek   +23 more
wiley   +1 more source

Impacts of Hemodynamic Support on Ventricular Arrhythmia Ablation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Data on the efficacy of hemodynamic support (HS) for protecting ventricular arrhythmia (VA) ablation in high‐risk heart failure (HF) patients with an impaired left ventricular function and its impact on mortality is limited. Objectives This study aimed to assess procedural efficacy, related complications, VA‐free survival, and ...
Denise Guckel, Moneeb Khalaph, Mustapha El Hamriti, Thomas Fink, Vanessa Sciacca, Maximilian Moersdorf, Guram Imnadze, Martin Braun, Angelika Costard‐Jäckle, René Schramm, Jan Gummert, Philipp Sommer, Christian Sohns   +12 more
wiley   +1 more source

The V6R/V4R Index: A Novel ECG Parameter for Identifying Idiopathic Ventricular Arrhythmias Originating From the Aortic Cusp

Journal of Cardiovascular Electrophysiology, EarlyView.
The V6R/V4R amplitude index is a novel and practical electrocardiographic parameter for identifying idiopathic ventricular arrhythmias originating from the aortic cusp. A cutoff >0.55 accurately distinguishes cusp from adjacent non‐cusp origins within the left ventricular outflow tract, facilitating targeted mapping and procedural planning.
Yoshihisa Naruse, Kohki Nakamura, Kanae Hasegawa, Toshihiko Tsuji, Machiko Miyoshi, Tatsuhiro Kataoka, Hideyuki Aoki, Yoshinori Okazaki, Shigeto Naito, Hiroshi Tada, and other members of the V6R/V4R Study Group, Tomoki Kaeriyama, Shigeki Horiguchi, Kaori Hisazaki, Takehito Sasaki, Kentaro Minami, Yutaro Kaneko, Taro Narumi, Makoto Sano, Yuichiro Maekawa   +19 more
wiley   +1 more source