Results 51 to 60 of about 2,626,293 (190)

Mean Platelet Volume in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia [PDF]

, 2015
Aim: Arrhythmogenic right ventricular cardiomyopathy or dysplasia (ARVC/D) is characterized by the gradual replacement of the right ventricular myocardium with fibrous and adipose tissue and can cause ventricular tachyarrhythmia in young patients.
Nuri Köse, Ahmet Kaya Bilge, Kose, Nuri, Göksel Güz, Kamil Adalet, ALTUN, İBRAHİM, Oz, Fahrettin, Biteker, Murat, Onur, Imran, Adalet, Kamil, Akin, Fatih, Murat Biteker, İbrahim Altun, İmran Önür, Guz, Goksel, Fatih Akın, Bilge, Ahmet Kaya, Fahrettin Öz, Akın, Fatih   +18 more
core   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source

Arrhythmogenic cardiomyopathy of the right ventricle. Predictive value of QT interval dispersion to assess arrhythmogenic risk and sudden death

Arquivos Brasileiros de Cardiologia, 2000
OBJECTIVE: To determine in arrhythmogenic right ventricular cardiomyopathy the value of QT interval dispersion for identifying the induction of sustained ventricular tachycardia in the electrophysiological study or the risk of sudden cardiac death ...
Márcio L. A. Fagundes, Ivan G. Maia, Fernando E. S. Cruz Fº, Paulo A. G. Alves, Silvia H. Boghossian, José Carlos Ribeiro, Roberto Sá   +6 more
doaj   +1 more source

Incidence of Childhood Dilated Cardiomyopathy in Sweden From 1991 to 2019: A National Population‐Based Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To study the incidence, survival, and mortality of dilated cardiomyopathy (DCM) in children in Sweden, 1991–2019. Methods Hospital records of 0–18‐year‐olds diagnosed with DCM over a 29‐year period were reviewed. The annual sex‐specific incidence rates of DCM were calculated as new disease cases, divided by the average Swedish same‐sex ...
Shalan Fadl, Stefan Särnblad, Tahir Taj, Håkan Wåhlander, Eva Fernlund, Jan Sunnegårdh   +5 more
wiley   +1 more source

Different Prognostic Value of Functional Right Ventricular Parameters in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia [PDF]

, 2014
BACKGROUND -The value of standard two-dimensional transthoracic echocardiographic (TTE) parameters for risk stratification in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is controversial. METHODS AND RESULTS -
Lüscher, Thomas F, Lüscher, Thomas F., Medeiros-Domingo, Argelia, Tanner, Felix C, Biaggi, Patric, Baldinger, Samuel H, Mueller-Burri, Andreas S, Vecchiati, Alessandra, Baldinger, Samuel Hannes, Haegeli, Laurent M, Jenni, Rolf, Held, Leonhard, Rüeger, Sina, Medeiros Domingo, Argelia, Manka, Robert, Duru, Firat, Delacrétaz, Etienne, Brunckhorst, Corinna, Fontaine, Guy, Tanner, Felix C., Mueller-Burri, Andreas S., Saguner, Ardan Muammer, Saguner, Ardan M   +22 more
core   +2 more sources

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Hypertrophic cardiomyopathy and ultra-endurance running - two incompatible entities? [PDF]

, 2011
Regular and prolonged exercise is associated with increased left ventricular wall thickness that can overlap with hypertrophic cardiomyopathy (HCM). Differentiating physiological from pathological hypertrophy has important implications, since HCM is the ...
Sanjay K Prasad, Papadakis, M, Sharma Sanjay, Prasad, Sanjay K., Chandra, N, Prasad, SK, O'Hanlon, Rory, O'Hanlon Rory, Papadakis, Michael, O'Hanlon, R, Chandra, Navin, Prasad Sanjay K, Michael Papadakis, Sharma, Sanjay, Chandra Navin, Papadakis Michael, Rory O'Hanlon, Wilson, MG, Wilson, Mathew G., Wilson Mathew G, Sanjay Sharma, Sharma, S, Mathew G Wilson, Navin Chandra   +23 more
core   +1 more source

Natural Course of Electrocardiographic Features in Arrhythmogenic Right Ventricular Cardiomyopathy and Their Relation to Ventricular Arrhythmic Events

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Electrocardiographic abnormalities are common in arrhythmogenic right ventricular cardiomyopathy and are included in the 2010 Task Force Criteria. Their time course, however, remains uncertain.
Anneli Svensson, Henrik Kjaerulf Jensen, Machteld J. Boonstra, Marianne Tétreault‐Langlois, Pia Dahlberg, Henning Bundgaard, Alex Hørby Christensen, Rebecca T. Rylance, Jesper H. Svendsen, Julia Cadrin‐Tourigny, Anneline S. J. M. te Riele, Pyotr G. Platonov   +11 more
doaj   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Usefulness of inducible ventricular tachycardia to predict long-term adverse outcomes in arrhythmogenic right ventricular cardiomyopathy

, 2013
The role of the electrophysiologic (EP) study for risk stratification in patients with arrhythmogenic right ventricular cardiomyopathy is controversial.
Lüscher, Thomas F, Schwyzer, Moritz A., Medeiros-Domingo, Argelia, Lüscher, Thomas F., On, Chol-Jun, Haegeli, Laurent M, Haegeli, Laurent M., Hürlimann, David, Saguner, Ardan M., Schwyzer, Moritz A, Held, Leonhard, Wolber, Thomas, Steffel, Jan, Rüeger, Sina, Duru, Firat, Krasniqi, Nazmi, Brunckhorst, Corinna, Saguner, Ardan M   +17 more
core   +1 more source