Results 101 to 110 of about 330,749 (304)

Characterization of arsenic-rich waste slurries generated during gallium arsenide wafer lapping and polishing [PDF]

, 2009
The toxicology of gallium arsenide is well established; it is classified by the state of California as a known carcinogen. Consequently, environmental aspects of GaAs wafer manufacture are coming under greater scrutiny, with the cost of waste disposal ...
Keenan, H.E., Torrance, K.
core  

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

Analysis of Arsenic Speciation Distribution in Agaric, Shiitake Mushroom, Matsutake and Agrocybe by IC-ICP-MS Method

Shipin gongye ke-ji
To analyze the speciation distribution of arsenic in agaric, shiitake mushroom, matsutake and agrocybe, the ion chromatography-inductive coupled plasma mass spectrometer (IC-ICP-MS) was used to determine arsenobetaine, dimethyl arsenic, arsenous acid ...
Xiaoping WANG, Zhongying LIU, Yang ZHONG, Dingqiu ZHANG, Yang LU, Minmin ZHU, Hongyi ZHENG, Yexin HE, Xin WANG, Taorui HUANG, Zubin JIANG   +10 more
doaj   +1 more source

Ignorance and Blame [PDF]

, 2019
Sometimes ignorance is a legitimate excuse for morally wrong behavior, and sometimes it isn’t. If someone has secretly replaced my sugar with arsenic, then I’m blameless for putting arsenic in your tea.
Miller, Daniel J.
core  

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study

Environmental Health, 2019
Background Growing evidence indicates that in utero arsenic exposures in humans may increase the risk of adverse health effects and development of diseases later in life. This study aimed to evaluate potential health risks of in utero arsenic exposure on
Panida Navasumrit, Krittinee Chaisatra, Jeerawan Promvijit, Varabhorn Parnlob, Somchamai Waraprasit, Chalida Chompoobut, Ta Thi Binh, Doan Ngoc Hai, Nguyen Duy Bao, Nguyen Khac Hai, Kyoung-Woong Kim, Leona D. Samson, Joseph H. Graziano, Chulabhorn Mahidol, Mathuros Ruchirawat   +14 more
doaj   +1 more source

Don't Drink the Water: Water in 65 Texas Communities Contains Toxic Levels of Arsenic, but State Fails to Advise Citizens to Use Alternative Water Supplies [PDF]

, 2016
The water contamination crisis in Flint, Michigan, threw a national spotlight on problems with drinking water systems that extend far beyond one state and that are more profound than just pipes.
Abel Russ, Courtney Bernhardt, Eric Schaeffer, Kira Burkhart, Tom Pelton   +4 more
core  

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source