Results 101 to 110 of about 30,301 (244)

Efficacy of thankuni and grapes in arsenicosis-affected rat

open access: yesUkrainian Journal of Veterinary and Agricultural Sciences
This study was undertaken to observe the effects of Thankuni and grapes on hematological and biochemical parameters against arsenicosis in Long Evans rats. Sixty male rats were selected to perform the study.
Md. Feroz Mahmud   +6 more
doaj   +1 more source

Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1

open access: yesHaematologica, 2017
Aldehyde dehydrogenase 1A1 (ALDH1A1) activity is high in hematopoietic stem cells and functions in part to protect stem cells from reactive aldehydes and other toxic compounds.
Maura Gasparetto   +11 more
doaj   +1 more source

Ascorbic Acid Potentiation of Arsenic Trioxide Anticancer Activity Against Acute Promyelocytic Leukemia [PDF]

open access: bronze, 2009
Clément G. Yedjou   +5 more
openalex   +1 more source

Synergism of arsenic trioxide and MG132 in Raji cells attained by targeting BNIP3, autophagy, and mitochondria with low doses of valproic acid and vincristine [PDF]

open access: bronze, 2014
Victoria Cavaliere   +5 more
openalex   +1 more source

Oral arsenic trioxide in the treatment of relapsed acute promyelocytic leukaemia [PDF]

open access: yes, 2002
INTRODUTION: Arsenic trioxide (As2O3) induces a remission in over 90% of patients with relapsed acute promyelocytic leukaemia (APL). To date, only the intravenous (i.v.) preparation of As2O3 has been used.
Kwong, YL   +6 more
core   +2 more sources

Immunomodulatory Activity of Methanolic Extract of Carica papaya Leaf on Biochemical Markers and Serum Level of IL-1â in Breast Cancer-Induced Wistar Rats

open access: yesSokoto Journal of Medical Laboratory Science
The kidneys are crucial for eliminating toxins, but exposure to substances like arsenic can damage them. Arsenic trioxide, used in cancer treatment, is nephrotoxic.
Imafidon, E.*, Ofojebe, C.S.
doaj   +1 more source

Arsenic-Induced Pancreatitis

open access: yesCase Reports in Gastrointestinal Medicine, 2011
The introduction of all-trans retinoic acid (ATRA) and arsenic trioxide has brought about tremendous advancement in the treatment of acute promyelocytic myelogenous leukemia (APML).
Sean Connelly   +2 more
doaj   +1 more source

Arsenic trioxide down-regulates antiapoptotic genes and induces cell death in mycosis fungoides tumors in a mouse model [PDF]

open access: yes, 2017
Background: Mycosis fungoides (MF) is the most frequent cutaneous T-cell lymphoma (CTCL). Arsenic trioxide (As2O3) has recently been shown to be effective against leukemias, so we studied whether As2O3 induces apoptosis of CTCL cells in vitro. We further
Dummer, R.   +6 more
core  

Effects of Ethanolic Leaves Extract of Irvingia gabonensis on Arsenic Trioxide-Induced Liver damage in Wistar rats

open access: yesJournal of Applied Sciences and Environmental Management
The toxicity of drugs and other related agents attracts considerable attention from basic scientists to clinicians. Humankind has been passionate about the availability of cheap and readily available agent against organotoxicity.
S. B. Olukayode, S. O. Innih
doaj  

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