Results 81 to 90 of about 30,301 (244)

FORMULATION OF ORAL COMPOSITIONS COMPRISING ARSENIC TRIOXIDE AND METHODS OF USE THEREOF [PDF]

open access: yes, 2004
The present invention provides an oral formulation of arsenic trioxide (As2O3) for the treatment of a variety of hematological malignancies, including acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL).

core  

Analysis of gamma-glutamyltransferase in acute promyelocytic leukemia patients undergoing arsenic trioxide treatment [PDF]

open access: gold, 2021
Meijuan Sui   +6 more
openalex   +1 more source

Pulsed DC Sputter Deposition of Stable Turbostratic Boron Nitride Thin Films

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 8, 21 April 2026.
Boron nitride (BN) films are deposited by sputtering from a boron target. During deposition, a substrate bias voltage is applied between the plasma and the sample, which reduces excess boron in the film and enhances the crystallinity. This process prevents the formation of boric acid and ammonium borate hydrate.
Josef Schätz   +9 more
wiley   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang   +9 more
wiley   +1 more source

Rapid Reduction in Breast Cancer Mortality With Inorganic Arsenic in Drinking Water

open access: yesEBioMedicine, 2014
Background: Arsenic trioxide is effective in treating promyelocytic leukemia, and laboratory studies demonstrate that arsenic trioxide causes apoptosis of human breast cancer cells.
Allan H. Smith   +10 more
doaj   +1 more source

Effective delivery of arsenic trioxide to HPV-positive cervical cancer cells using optimised liposomes: a size and charge study [PDF]

open access: yes, 2018
Despite the success of arsenic trioxide (ATO) in treating haematological malignancies, its potential to treat solid tumours has not been fully exploited, owing to its dose-limiting toxicity and poor pharmacokinetics.
Akhtar, Anam   +4 more
core   +2 more sources

Engineering of Amygdalin Biosynthesis in Rice Endosperm for Pharmaceutical Production and Sitophilus oryzae Resistance

open access: yes
Plant Biotechnology Journal, EarlyView.
Ke Chen   +16 more
wiley   +1 more source

Cytotoxicity patterns of arsenic trioxide exposure on HaCaT keratinocytes

open access: yesClinical, Cosmetic and Investigational Dermatology, 2011
Udensi K Udensi1,2, Barbara E Graham-Evans1, Christian Rogers1, Raphael D Isokpehi1,21RCMI-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217; 2Center for Bioinformatics &amp ...
Udensi UK   +3 more
doaj  

Arsenic trioxide plus cisplatin/interferon α- 2b/doxorubicin/capecitabine combination chemotherapy for unresectable hepatocellular carcinoma

open access: yesHematology/Oncology and Stem Cell Therapy, 2011
BACKGROUND AND OBJECTIVES: The failure of existing treatments for liver cancer has recently been attribuuted to the existence of cancer stem cells, which are difficult to kill using current drugs due to their chemoresisttant properties as well as their ...
Ciprian Tomuleasa   +10 more
doaj   +1 more source

Efficacy and the Adverse Effects of Oral Versus Intravenous Arsenic for Acute Promyelocytic Leukemia: A Meta-Analysis of Randomized-Controlled Studies

open access: yesTechnology in Cancer Research & Treatment, 2020
Acute promyelocytic leukemia, a subtype of acute myeloid leukemia, is highly curable. In subgroup of patients with non-high-risk acute promyelocytic leukemia, intravenous arsenic trioxide plus all-trans-retinoic acid is considered the preferred regimen ...
Natthaporn Sasijareonrat MD   +3 more
doaj   +1 more source

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