Results 61 to 70 of about 96,549 (135)
Burmannic acid (BURA) boosts radiosensitivity in oral cancer: combined with x‐rays, it suppresses tumor growth while sparing normal cells by increasing reactive oxygen species (ROS, MitoSOX), causing G2/M arrest, sub‐G1 accumulation, mitochondrial dysfunction, DNA damage, and apoptosis; these effects are reversed by N‐acetylcysteine. Therefore, BURA is
Kun‐Han Yang +9 more
wiley +1 more source
Twisting the End Game: How Telomere Chromatin Modifications Shape Telomere Maintenance
Chromatin modifications on telomeres are linked to the mode of telomere DNA replication. A coupled feedforward loop model is proposed based on these to lock the ALT cancer cells in this alternative mode of telomere replication. ABSTRACT Cell division inevitably shortens telomeric DNA owing to the end‐replication problem.
Jie Wang +8 more
wiley +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
Potassium bromate assay by redox titrimetry using arsenic trioxide
Bromate, a disinfectant, is one of the analytes of interest in wastewater analysis. Environmental laboratories have a regulatory need for their measurements to be traceable to NIST standards.
Smeller, J.M.; Leigh, S.D.
core +1 more source
ABSTRACT Aim Hydraulic calcium silicate cements are widely employed in endodontics due to their excellent biocompatibility, bioactivity, sealing ability, and remineralisation potential. However, currently used products such as mineral trioxide aggregate (MTA) exhibit several limitations, including discolouration, cost, and poor handling properties ...
P. A. A. S. Prasad Kumara +6 more
wiley +1 more source
We report the clinical features and treatment outcome of 33 patients with multiple sclerosis who developed acute promyelocytic leukemia. Thirty patients were previously exposed to mitoxantrone.
Emanuele Ammatuna +9 more
doaj +1 more source
Rediscovering Arsenoacetic Acid [PDF]
Arsonoacetic acid, H₂O₃As¹CH₂COOH, and arsenoacetic acid, punitively [AsVCH₂COOH]₂ have been synthesised according to historical literature methods, and have been characterised using modern techniques.
Wilson, Peter Stanley
core
Effects of arsenic trioxide on human hepatoma cells. [PDF]
Siu Pak-yan.Thesis (M.Phil.)--Chinese University of Hong Kong, 2001.Includes bibliographical references (leaves 158-174).Abstracts in English and Chinese.Acknowledgement --- p.iAbstract --- p.ii摘要 --- p.ivContents --- p.viList of Figures and Tables --
core
Rapid Reduction in Breast Cancer Mortality With Inorganic Arsenic in Drinking Water
Background: Arsenic trioxide is effective in treating promyelocytic leukemia, and laboratory studies demonstrate that arsenic trioxide causes apoptosis of human breast cancer cells.
Allan H. Smith +10 more
doaj +1 more source
BACKGROUND AND OBJECTIVES: The failure of existing treatments for liver cancer has recently been attribuuted to the existence of cancer stem cells, which are difficult to kill using current drugs due to their chemoresisttant properties as well as their ...
Ciprian Tomuleasa +10 more
doaj +1 more source

