Multidisciplinary corroboration in differentiation syndrome: a case report
Background Differentiation syndrome (DS) is a life-threatening complication that may be seen in patients with acute promyelocytic leukaemia undergoing induction therapy with all-trans retinoic acid or arsenic trioxide.
Sayan Sarkar +4 more
doaj +1 more source
Thermogravimetric and distillation studies on mercury, antimony and arsenic sulfides [PDF]
Thermogravimetric studies were made on naturally occurring sulfides of mercury, antimony and arsenic to determine activation energies and Arrhenius rates of reaction in vacuum and in atmospheres of air and nitrogen. Of the three sulfides only antimony
Rao, P.D., Town, J.W.
core
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova +2 more
wiley +1 more source
FORMULATION OF ORAL COMPOSITIONS COMPRISING ARSENIC TRIOXIDE AND METHODS OF USE THEREOF [PDF]
The present invention provides an oral formulation of arsenic trioxide (As2O3) for the treatment of a variety of hematological malignancies, including acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL).
core
Deducing signaling pathways from parallel actions of arsenite and antimonite in human epidermal keratinocytes. [PDF]
Inorganic arsenic oxides have been identified as carcinogens in several human tissues, including epidermis. Due to the chemical similarity between trivalent inorganic arsenic (arsenite) and antimony (antimonite), we hypothesized that common intracellular
Cánovas, Angela +7 more
core
Indomethacin-Enhanced Anticancer Effect of Arsenic Trioxide in A549 Cell Line: Involvement of Apoptosis and Phospho-ERK and p38 MAPK Pathways [PDF]
Background. Focusing on novel drug combinations that target different pathways especially apoptosis and MAPK could be a rationaleforcombinationtherapyinsuccessfultreatmentoflungcancer.Concurrentuseofcyclooxygenase(COX)inhibitorswith arsenictrioxide(ATO ...
Amirheidari, Bagher +5 more
core +2 more sources
Berberine enhances inhibition of glioma tumor cell migration and invasiveness mediated by arsenic trioxide [PDF]
Background Arsenic trioxide (As2O3) exhibits promising anticarcinogenic activity in acute promyelocytic leukemic patients and induces apoptosis in various tumor cells in vitro.
Tseng-Hsi Lin +64 more
core +1 more source
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini +7 more
wiley +1 more source
Combination Effect Of Low Dose of Arsenic Trioxide And AZT On Viability And Metabolic Activity Of NB4 Cell Line [PDF]
Background and Aim: Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia. APL is characterized by a balanced reciprocal translocation between chromosomes 15 and 17, t(517)).
R Mirzaee Khalilabadi +6 more
doaj +1 more source

