Results 51 to 60 of about 13,610 (191)
, 2017 Heat shock protein 70 (HSP70) has been shown to be a substrate of Polo-like kinase 1 (PLK1), and it prevents cells arrested in mitosis by arsenic trioxide (ATO) from dying.
Chen, Yu-Ju;Lai, Kuo-Chu;Kuo, Hsiao-Hui;Chow, Lu-Ping;Yih, Ling-Huei;Lee, Te-Chang +1 more
core +1 more source
Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer
Cancer Science, EarlyView.Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo +6 more
wiley +1 more source
Journal of the Formosan Medical Association, 2014 The leakage of arsenic trioxide paste from tooth fillings has been associated with widespread necrosis of the supporting periodontal tissues. This report describes two cases of arsenic trioxide paste-induced gingival and localized alveolar bone necrosis ...
Gin Chen, Po-Ta Sung
doaj +1 more source
Cell Proliferation, EarlyView.This study presents an NDs‐mediated localised combination strategy that integrates autophagy inhibition with low‐dose ATO sensitization, enabling effective tumour suppression while enhancing safety. NDs‐mediated autophagy blockade enhances ATO efficacy while minimising systemic toxicity, highlighting a promising approach for solid tumour treatment ...
Yiliu Wang +8 more
wiley +1 more source
Haematologica, 2020 Daily intravenous arsenic trioxide administered with all-trans retinoid acid, the standard-of-care for acute promyelocytic leukemia, is costly and challenging to administer.
Farhad Ravandi +13 more
doaj +1 more source
An update on the landscape of collagen bioactive fragments
The FEBS Journal, EarlyView.The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley +1 more source
Arsenic transport in plants [PDF]
, 2012 Arsenic (As), a metalloid occurring ubiquitously in nature in organic and inorganic forms, is classified as a potent carcinogen. Among the inorganic forms which are more toxic, AsIII has a high affinity to bind with sulfhydryl groups of the amino acid ...
Ali, Waqar
core
International Endodontic Journal, EarlyView.ABSTRACT Aim Hydraulic calcium silicate cements are widely employed in endodontics due to their excellent biocompatibility, bioactivity, sealing ability, and remineralisation potential. However, currently used products such as mineral trioxide aggregate (MTA) exhibit several limitations, including discolouration, cost, and poor handling properties ...
P. A. A. S. Prasad Kumara +6 more
wiley +1 more source
Potassium bromate assay by redox titrimetry using arsenic trioxide
, 2003 Bromate, a disinfectant, is one of the analytes of interest in wastewater analysis. Environmental laboratories have a regulatory need for their measurements to be traceable to NIST standards.
Smeller, J.M.; Leigh, S.D.
core +1 more source
Arsenic trioxide in the treatment of haematological malignancies
, 2004 Arsenic trioxide (AS2O3) for leukaemia treatment was described a century ago. Recent resurgence in the use of arsenic trioxide is related to its high efficacy in acute promyelocytic leukaemia (APL).
Kwong, YL
core +1 more source