Results 51 to 60 of about 96,549 (135)

HSP70 colocalizes with PLK1 at the centrosome and disturbs spindle dynamics in cells arrested in mitosis by arsenic trioxide

, 2017
Heat shock protein 70 (HSP70) has been shown to be a substrate of Polo-like kinase 1 (PLK1), and it prevents cells arrested in mitosis by arsenic trioxide (ATO) from dying.
Chen, Yu-Ju;Lai, Kuo-Chu;Kuo, Hsiao-Hui;Chow, Lu-Ping;Yih, Ling-Huei;Lee, Te-Chang, 周綠蘋   +1 more
core   +1 more source

The Roles of EETs in Neurological Disorders

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Epoxyeicosatrienoic acids (EETs), derived from arachidonic acid (ARA) via cytochrome P450 (CYP450) enzymes, are produced in nearly all human tissues and exert a wide range of beneficial effects. This review summarizes the roles and potential mechanisms of EETs in neurological disorders, with a focus on cerebrovascular diseases, epilepsy, Parkinson's ...
Rong Tang, Mengya Li, Banglian Hu, Guoqiang Fei, Honghua Zheng, Xin Wang, Jing Ding   +6 more
wiley   +1 more source

Multidisciplinary corroboration in differentiation syndrome: a case report

Journal of Medical Case Reports, 2021
Background Differentiation syndrome (DS) is a life-threatening complication that may be seen in patients with acute promyelocytic leukaemia undergoing induction therapy with all-trans retinoic acid or arsenic trioxide.
Sayan Sarkar, Priya Ghosh, Anisha Gehani, Niharendu Ghara, Parthasarathi Bhattacharyya   +4 more
doaj   +1 more source

Method For Inhibiting Cancer Using Arsenic Trioxide [PDF]

, 2008
The Invention Provides A Method For Treating Cancers That Are Dependent On Cyclin D1 For Proliferation, Survival, Metastasis And Differentiation, Involving Administering A Composition Containing An Effective Amount Of Arsenic Trioxide To An Affected ...

core   +4 more sources

Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications

Food Frontiers, Volume 7, Issue 5, September 2026.
The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley   +1 more source

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou, Jing Lin, Yu Chen, Jiaqi Zhao   +3 more
wiley   +1 more source

Nutlin-3 overcomes arsenic trioxide resistance and tumor metastasis mediated by mutant p53 in Hepatocellular Carcinoma [PDF]

, 2014
Background: Arsenic trioxide has been demonstrated as an effective anti-cancer drug against leukemia and solid tumors both in vitro and in vivo. However, recent phase II trials demonstrated that single agent arsenic trioxide was poorly effective against ...
Xuan Song, Chen, Xi, Lianxin Liu, Dalong Yin, Jiaren Liu, Li, Yuejin, Zhaoyang Lu, Hongchi Jiang, Yuejin Li, Song, Xuan, Jiabei Wang, Jiang, Hongchi, Yin, Dalong, Sun, Boshi, Tongsen Zheng, Shuyi Qi, Xie, Changming, Lu, Zhaoyang, Pan, Shangha, Liu, Jiaren, Xi Chen, Meng, Xianzhi, Changming Xie, Wang, Jiabei, Boshi Sun, Shangha Pan, Xianzhi Meng, Zheng, Tongsen, Liu, Lianxin, Yingjian Liang, Liang, Yingjian, Qi, Shuyi   +31 more
core   +1 more source

Phase II multicenter study of arsenic trioxide, ascorbic acid and dexamethasone in patients with relapsed or refractory multiple myeloma

Haematologica, 2006
Arsenic trioxide induces growth inhibition and apoptosis in multiple myeloma cell lines. Reducing glutathione by ascorbic acid may enhance the efficacy of arsenic trioxide.
KL Wu, M Beksac, J van Droogenbroeck, S Amadori, S Zweegman, P Sonneveld   +5 more
doaj  

Magnetic Nanomedicine for Cancer: Mechanisms, Modalities, and Translation

Nano Select, Volume 7, Issue 9, September 2026.
At the convergence of nanotechnology, precision oncology and intelligent therapeutics, magnetic nanoparticles (MNPs) are redefining how cancer is detected, targeted and treated. This review critically examines the mechanisms enabling their integration in imaging, targeted drug delivery and magnetic hyperthermia, while exploring how intelligent design ...
Shivani Kadam, Rahul M. Sonavale, Ratnesh Das, Jayant Pawar, Nutan Shukla, Zhengyou Li, Girish R. Pathade, Nishabh Kushwaha, Asha Patel, Sushilkumar A. Jadhav, Samuel B. Adeloju   +10 more
wiley   +1 more source

Combination Effect Of Low Dose of Arsenic Trioxide And AZT On Viability And Metabolic Activity Of NB4 Cell Line [PDF]

پیاورد سلامت, 2011
Background and Aim: Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia. APL is characterized by a balanced reciprocal translocation between chromosomes 15 and 17, t(517)).
R Mirzaee Khalilabadi, H Mardani Valandani, D Bashshash, N Einollahi, K Ali Moghaddam, A Ghavamzadeh, SH Ghaffari   +6 more
doaj   +1 more source