Results 141 to 150 of about 4,514 (237)

Notes on Arsenic [PDF]

Science, 1893
openaire   +3 more sources

FB23‐2 and Cisplatin Synergize to Inhibit Head and Neck Squamous Cell Carcinoma by Targeting the XPF/ERCC1 Complex

Cancer Science, EarlyView.
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang, Hongshi Cai, Yue Zhu, Jianfeng Liang, Hongyu Li, Fan Song, Ziyi Wang, Jinsong Hou   +7 more
wiley   +1 more source

Neurotoxicology of warfare arsenical, diphenylarsinic acid in humans and experimental models. [PDF]

Chemosphere
Saggu S, Srivastava RK, McCormick L, Agarwal A, Khan MM, Athar M.   +5 more
europepmc   +1 more source

Ex vivo exposures to arsenite and its methylated trivalent metabolites alter gene transcription in mouse sperm cells. [PDF]

Toxicol Appl Pharmacol, 2022
Shang B, Venkatratnam A, Hartwell H, Douillet C, Cable P, Liu T, Zou F, Ideraabdullah FY, Fry RC, Stýblo M.   +9 more
europepmc   +1 more source

Frontline ATRA‐ATO Therapy for Acute Promyelocytic Leukemia in Japan: Results From the Prospective Multicenter FBMTG‐APL2017 Trial

Cancer Science, EarlyView.
FBMTG‐APL2017: First prospective multicenter trial evaluating frontline ATRA‐ATO therapy for newly diagnosed APL in Japan, encompassing both low–intermediate (n = 65) and high‐risk (n = 16) patients. Excellent outcomes (95% CR, 94% 3‐year DFS) with comparable efficacy between risk groups (DFS: 97% vs.
Ken Takase, Tomohiko Kamimura, Takuro Kuriyama, Takahito Tokuyama, Hideho Henzan, Yoshikane Kikushige, Ilseung Choi, Yutaka Imamura, Akio Mori, Shuki Ohya, Noriaki Kawano, Koji Yonemoto, Mine Harada, Koichi Akashi, Toshihiro Miyamoto   +14 more
wiley   +1 more source

Density Functional Theory Calculation May Confirm Arsenic-Thiol Adhesion as the Primary Mechanism of Arsenical Toxicity. [PDF]

ACS Omega
Tsai MH, Lin YT.
europepmc   +1 more source

Arsenic and cancer: Evidence and mechanisms. [PDF]

Adv Pharmacol, 2023
Speer RM, Zhou X, Volk LB, Liu KJ, Hudson LG.   +4 more
europepmc   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

Inhibition of PHPT1 by phenylarsonic acids.

Dalton Trans
Keyes ED, Hollow SE, Oblad P, Johnstone TC, Barrios AM.   +4 more
europepmc   +1 more source

Inhibition of BRD4 prevents peribronchial fibrosis in mice with cutaneous lewisite exposure. [PDF]

Front Mol Biosci
Zeng H, Singh P, Sinha R, Stephens CT, Ahmad A, Athar M, Antony VB.   +6 more
europepmc   +1 more source