Results 191 to 200 of about 8,884 (302)

Droughts and human impact in the ancient Uaymil region of the Maya lowlands inferred from a 2800‐year sedimentary archive at Lake Kaná, Mexico

Boreas, EarlyView.
The relationship between the climate and societal transformation in Maya lowlands has long been debated, particularly the role of drought in shaping the civilization trajectory during the Classic Period. A high‐resolution, multi‐proxy, geochemical record from Lake Kaná, located in the underexplored Uaymil region of the Yucatán Peninsula in Mexico ...
Haydar B. Martinez‐Dyrzo, Priyadarsi D. Roy, Benjamin Gwinneth, Irma G. Vargas‐Martinez, Alejandro A. Aragon‐Moreno, Roger Medina‐Gonzales   +5 more
wiley   +1 more source

Inhibition of PHPT1 by phenylarsonic acids.

Dalton Trans
Keyes ED, Hollow SE, Oblad P, Johnstone TC, Barrios AM.   +4 more
europepmc   +1 more source

Arsenic efflux mechanisms in ectomycorrhizal mushrooms Hebeloma bulbiferum and Hebeloma sinapizans. [PDF]

Appl Microbiol Biotechnol
Šnábl J, Pelešková G, Kaňa A, Šnáblová M, Leonhardt T, Borovička J, Sácký J.   +6 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Inhibition of BRD4 prevents peribronchial fibrosis in mice with cutaneous lewisite exposure. [PDF]

Front Mol Biosci
Zeng H, Singh P, Sinha R, Stephens CT, Ahmad A, Athar M, Antony VB.   +6 more
europepmc   +1 more source

Multiplexed Transcriptomics for Screening Drug Combinations and Defining the Mechanism of Action of HCC Therapeutics at Single‐Cell Resolution

Cell Proliferation, EarlyView.
We designed a framework for screening clinical drug combinations with anti‐hepatocellular carcinoma (HCC) activity, comprising four parts: primary screening, single‐cell screening, functional validation, and mechanism research. High‐throughput single‐cell screening identifies HY (HHT and YM155) as a potent anti‐HCC drug combination, validated by in ...
Mengmeng Jiang, Haide Chen, Guoxia Wen, Yuqing Mei, Wenzhao Zhou, Bin Xu, Tingyue Zhang, Guangyan Li, Junqing Wu, Xiaoping Han, Xudong Fu, Guoji Guo, Jingjing Wang   +12 more
wiley   +1 more source

A new type of ArsR transcriptional repressor controls transcription of the arsenic resistance operon of Arsenicibacter rosenii SM-1. [PDF]

mLife
Zhang Y, Wu W, Huang K, Zhao FJ.
europepmc   +1 more source

Arsen [PDF]

Fresenius' Zeitschrift für analytische Chemie, 1919
S. Goy, null Forster, null Riechelmann
openaire   +1 more source

Outbreak of poisoning by sodium hydrogen methylarsonate (MSMA)—an arsenic‐based herbicide—in horses in Brazil

Equine Veterinary Journal, EarlyView.
Abstract Background Arsenic poisoning in horses is rarely reported in the literature. However, arsenic compounds can be present in rodenticides, pesticides, and herbicides, representing a potential source of accidental exposure for horses. Objective To describe the epidemiological, clinical, and laboratory findings from a herd of 31 horses exposed to ...
Gabriella Faria Pereira, Maria Clara Hornich Blimbliem, Anna Laura Previato Rosa Machado, Junara Bianca Rosa Abdala, Geison Morel Nogueira, Hugo Shisei Toma, Tatiane Furtado de Carvalho, Diego José Zanzarini Delfiol   +7 more
wiley   +1 more source