Results 201 to 210 of about 37,464 (275)
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Arsenite induces ferroptosis in the neuronal cells via activation of ferritinophagy

Food and Chemical Toxicology, 2021
Ferroptosis is a novel form of cell death that involves in the pathophysiological process of diverse brain diseases. However, how arsenite induces ferroptosis in the neuronal cells remains unsolved. In this study, by using in vitro and in vivo models, we
Shuqun Cheng, Qianghu Tang, Zhen Zou
exaly   +2 more sources

Oxidative stress: One potential factor for arsenite-induced increase of N6-methyladenosine in human keratinocytes

Environmental Toxicology and Pharmacology, 2019
N6-methyladenosine (m6A) modification is affected by oxidative stress and gets involved in arsenite toxicity. However, whether oxidative stress is one factor in arsenite-induced alteration of m6A levels remains unclear. Here, reactive oxygen species (ROS)
Tianhe Zhao   +2 more
exaly   +2 more sources

Heterozygous disruption of beclin 1 mitigates arsenite-induced neurobehavioral deficits via reshaping gut microbiota-brain axis

Journal of Hazardous Materials, 2020
Gut microbiota is intimately involved in numerous aspects of human health. Arsenite expouse can perturb gut microbiota and is linked to increased susceptibility of individual to arsenite-related diseases.
Yinyin Xia, Zhen Zou, Chang Chen
exaly   +2 more sources

The role of the rice aquaporin Lsi1 in arsenite efflux from roots [PDF]

open access: yesNew Phytologist, 2010
When supplied with arsenate (As(V)), plant roots extrude a substantial amount of arsenite (As(III)) to the external medium through as yet unidentified pathways.
Fang-Jie Zhao   +2 more
exaly   +2 more sources

H3K18 lactylation promotes the progression of arsenite-related idiopathic pulmonary fibrosis via YTHDF1/m6A/NREP.

Journal of Hazardous Materials, 2023
As epigenetic modifications, lactylation and N6-methyladenosine (m6A) have attracted wide attention. Arsenite is an environmental pollutant that has been proven to induce idiopathic pulmonary fibrosis (IPF).
Peiwen Wang   +9 more
semanticscholar   +1 more source

The arsenite oxidase genes (aroAB) in novel chemoautotrophic arsenite oxidizers

Biochemical and Biophysical Research Communications, 2007
Six novel bacterial strains were isolated from the environment which can oxidize arsenite [As(III)] to the less mobile form arsenate [As(V)] coupled to CO(2) fixation under either aerobic or denitrifying conditions. PCR primers were designed to the conserved molybdopterin domain of the large subunit of arsenite oxidase in order to identify the arsenite
Gerben J Zylstra, L Y Young
exaly   +3 more sources

Arsenite induces testicular oxidative stress in vivo and in vitro leading to ferroptosis.

Ecotoxicology and Environmental Safety, 2020
Ferroptosis is a newly identified form of cell death characterized by accumulation of intracellular iron and requirement of lipid peroxidation. However, whether arsenite triggers testicular cell death via ferroptosis remains unclear. In this study, after
P. Meng   +8 more
semanticscholar   +1 more source

microRNA-21, via the HIF-1α/VEGF signaling pathway, is involved in arsenite-induced hepatic fibrosis through aberrant cross-talk of hepatocytes and hepatic stellate cells.

Chemosphere, 2020
Long-term exposure to arsenic, a widely distributed environmental toxicant, may result in damage to various organs, including the liver. Mice exposed chronically to arsenite developed hepatic damage, inflammation, and fibrosis, as well as increased ...
Jing Sun   +9 more
semanticscholar   +1 more source

Arsenite oxidation by the heterotroph Hydrogenophaga sp. str. NT-14: the arsenite oxidase and its physiological electron acceptor

open access: yesBiochimica Et Biophysica Acta - Bioenergetics, 2004
Heterotrophic arsenite oxidation by Hydrogenophaga sp. str. NT-14 is coupled to the reduction of oxygen and appears to yield energy for growth.
Joanne M Santini
exaly   +2 more sources

Arsenite transport into paddy rice ( Oryza sativa ) roots

open access: yesNew Phytologist, 2003
Here the mechanism of arsenite transport into paddy rice (Oryza sativa) roots, uptake of which is described by Michaelis-Menten kinetics, is reported. A recent study on yeast (Saccharomyces cerevisiae) showed that undissociated arsenite (its pKa is 9.2 ...
Andrew A Meharg
exaly   +2 more sources

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