Results 71 to 80 of about 37,464 (275)

A keratin 18 transgenic zebrafish Tg(k18(2.9):RFP) treated with inorganic arsenite reveals visible overproliferation of epithelial cells

open access: yes, 2009
Inorganic arsenic has strong human carcinogenic potential, but the availability of an animal model to study toxicity is extremely limited. Here, we used the transgenic zebrafish line Tg(k18(2.9):RFP) as an animal model to study arsenite toxicity.
陳曜鴻; Chen, Yau-hung; Wang, Y. H.; Lin, Y. J.; Wu, T. N.; Tsai, H. J.   +3 more
core   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida   +7 more
wiley   +1 more source

Effect of green tea extract (Camellia sinensis) on kidney toxicity induced by sodium arsenite: a stereological study

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2016
Background and Objective: Sodium Arsenite is an environmental pollutant which can generate free radicals causing tissue damage. This study was done to evaluate the effect of Green Tea (GTE), as a strong antioxidant, on kidney tissue in mice treated with ...
Shariatzadeh SMA   +3 more
doaj  

A Hyperthermoactive-Cas9 Editing Tool Reveals the Role of a Unique Arsenite Methyltransferase in the Arsenic Resistance System of Thermus thermophilus HB27

open access: yesmBio, 2021
Arsenic detoxification systems can be found in a wide range of organisms, from bacteria to humans. In a previous study, we discovered an arsenic-responsive transcriptional regulator in the thermophilic bacterium Thermus thermophilus HB27 (TtSmtB).
Giovanni Gallo   +9 more
doaj   +1 more source

Multielemental Analysis in Rice Grains by Total Reflection X‐Ray Fluorescence

open access: yesX-Ray Spectrometry, EarlyView.
ABSTRACT Rice (Oryza sativa) is a staple food cultivated worldwide and represents a significant source of essential nutrients for humans. However, this cereal may also contain potentially toxic elements including chromium, arsenic, and lead typically present at trace concentrations (ng.g−1).
F. T. S. Tsuyama   +8 more
wiley   +1 more source

Depth-resolved abundance and diversity of arsenite-oxidizing bacteria in the groundwater of Beimen, a blackfoot disease endemic area of southwestern Taiwan

open access: yes, 2013
The role of arsenite oxidizers in natural attenuation of arsenic pollution necessitates studies on their abundance and diversity in arsenic-contaminated aquifers.
Kar, Sandeep   +6 more
core   +1 more source

Role of human RNase 7 in neuronal and glial cell models: moving towards an unexpected new functional link

open access: yesThe FEBS Journal, EarlyView.
Human RNase 7 is known to exert antimicrobial activity in epithelial tissues. Here, using SH‐SY5Y and U‐87 MG, neuroblastoma and glioblastoma cell lines, respectively, we found that RNase 7 enhances immune responses to LPS stimulation by reducing the expression of pro‐inflammatory cytokines, nitric oxide, and ROS.
Rosanna Culurciello   +9 more
wiley   +1 more source

Cellular Responses to Arsenite and Cadmium - Mechanisms of Toxicity and Defense in Saccharomyces cerevisiae

open access: yes, 2016
All biological systems have to cope with a wide range of metals that are present in the environment. Metals can be essential or beneficial for life, inert or non-essential and toxic, often depending on their chemical form and concentration.
Jacobson, Therese
core   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

open access: yesThe FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia   +7 more
wiley   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

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