Results 61 to 70 of about 21,704 (242)

Xanthatin‐13‐(Pyrrolidine‐2‐Carboxylic Acid), a Sesquiterpene Lactone Isolated From Burdock Leaf, Attenuated Aβ25‐35 Toxicity and Memory Deficits in a Pharmacological Mouse Model of Alzheimer's Disease

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a severe form of dementia, which occurrence increases with age and lifestyle conditions. It is characterized by amyloid protein accumulation forming senile plaques, hyperphosphorylated tau protein forming neurofibrillary tangles, neuroinflammation, and oxidative stress, leading to synapse loss and cell death ...
Charlyne Barry‐Simonnet, Lucie Crouzier, Tristan Moujellil‐Legagneur, Hamza Chaieb‐Errass, Yanis A. Idres, Karine Ferrare, Marc Rolland, Guillaume Cazals, Patrick Poucheret, Tangui Maurice, Didier Tousch   +10 more
wiley   +1 more source

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

VIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu, Linlin Cao, Chenhuan Ding, Chen Wang, Yi Lai, Dan Ru, He Li, Wei Xu   +7 more
wiley   +1 more source

Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang, Teng‐Fei Li, Tian‐Yu Wang, Huan‐Hai Liu   +3 more
wiley   +1 more source

Annual survival in a dynamic species: pronghorn survival patterns across their northern range

Wildlife Biology, EarlyView.
Quantifying variation in demographic patterns, such as survival and recruitment, is critical for understanding population dynamics and informing evidence‐based and adaptive wildlife management. In this study, we leverage an extensive dataset from over 1000 GPS collared pronghorn Antilocapra americana to provide the first large‐scale evaluation of ...
Molly C. McDevitt, Anna K. Moeller, Andrew J. Lindbloom, Kelly Proffitt, Joshua J. Millspaugh, Paul M. Lukacs   +5 more
wiley   +1 more source

Apex predators exploit advantageous snow conditions across hunting modes

Journal of Animal Ecology, EarlyView.
Advantageous snow conditions—in terms of snow depth and density—are among the most important features of the winter landscape for two apex predators, regardless of hunting strategy. In a warming climate, the knock‐on effects of a diminishing snowpack may reduce the hunting success of multiple large carnivore species.
Benjamin K. Sullender, Taylor R. Ganz, Ross Mower, Jessica D. Lundquist, Brian N. Kertson, Thomas M. Newsome, Aaron J. Wirsing, Laura R. Prugh   +7 more
wiley   +1 more source

De Stupro: First Insights on Rape and Its Prosecution in Maltese Courts (1701–10)

Journal for Eighteenth-Century Studies, EarlyView.
Abstract This article constitutes a first in‐depth investigation of rape and the prosecution of this crime in early eighteenth‐century Malta. The research, which is based on sixteen rape accusations claimed at the secular courts in Malta between 1701 and 1710, has analysed cases categorized as ‘simple rape’, ‘violent rape’ and rape committed under the ...
Vanessa Buhagiar
wiley   +1 more source

Allocation of nitrogen and phosphorus in the leaves, stems, and roots of Artemisia: a case study in phylogenetic control

Frontiers in Plant Science
IntroductionThe allocation of nitrogen (N) and phosphorus (P) among plant organs is an important strategy affecting growth and development as well as ecological processes in terrestrial ecosystems.
Dechun Jiang, Haiyang Gong, Haiyang Gong, Karl J. Niklas, Zhiqiang Wang, Zhiqiang Wang   +5 more
doaj   +1 more source

Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)

Allergy, EarlyView.
This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.
Qingxiu Xu, Xuan Yuan, Wang Liao, Hao Chen, Qing Jiang, Lin Yang, Jin Liu, Le Li, Nan Huang, Wenjing Li, Yaqi Yang, Dongxia Ma, Jun Bai, Zhihai Xie, Rongfei Zhu   +14 more
wiley   +1 more source

Molecular IgE Reactivity Profiling With Micro‐Arrayed Allergens Reveals Distinct Interregional Patterns of Sensitization and a Hypoallergenic Region in Türkiye

Allergy, EarlyView.
A prospective, systematic and cross‐sectional population study was performed involving 1000 adult subjects from five centers representing different climatic areas of Türkiye (Turkey). Molecular IgE profiling demonstrated substantial interregional variation and identified a hypoallergenic region in the easternmost area with a continental climate.
Alp Kazancioglu, Huey‐Jy Huang, Sengul Aksakal, Ismet Bulut, Maria‐Roxana Buzan, Kuan‐Wei Chen, Monica Daniela Cotarcă, Alexandra Dubovets, Pia Gattinger, Okan Gulbahar, Ali Fuat Kalyoncu, Alexander Karaulov, Evgenii Kozlov, Carmen Panaitescu, Thomas Schlederer, Daria Trifonova, Mikhail Tulaev, Murat Turk, Susanne Vrtala, Milena Weber, Lauriana‐Eunice Zbîrcea, Bulent Enis Sekerel, Rudolf Valenta   +22 more
wiley   +1 more source

Effect of essential oils of Artemisia. Zataria and Myrtus on Trichomonas vaginalis

Journal of Medicinal Plants, 2003
Considering the high prevalence of Tricomonas vaginalis (TV) in women and the known side effects of metronidazol and giving importance to herbal drug therapy in order to reduce side effects in the recent decades, this study with the effect of essential ...
M Azadbakht, H Ziai, F Abdollahi, B Shabankhani   +3 more
doaj