Declining Burden of Plasmodium vivax in a Population in Northwestern Thailand from 1995 to 2016 before Comprehensive Primaquine Prescription for Radical Cure. [PDF]
, 2020 All Plasmodium cases have declined over the last decade in northwestern Thailand along the Myanmar border. During this time, Plasmodium vivax has replaced Plasmodium falciparum as the dominant species. The decline in P.
Carrara, Verena I +6 more
core
Cannabis‐Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies
Tropical Medicine &International Health, EarlyView.ABSTRACT Objective This study aims to evaluate preclinical studies on the effects and toxicity of cannabis‐derived compounds against Plasmodium sp. Methods A literature search was conducted in Web of Science, PubMed, Scopus and LILACS databases until December 2024. Studies that assessed the activity or toxicity of cannabis against Plasmodium sp.
Tácio de Mendonça Lima +5 more
wiley +1 more source
Tropical Medicine and Infectious DiseaseBackground: Recent setbacks in malaria control in Comoros demand a reassessment of its evolving epidemiology. Methods: Using the Global Burden of Disease (GBD) Study 2021 data, we analyzed malaria trends from 2010 to 2021, stratified by sex.
Sheng Zhou +8 more
doaj +1 more source
Artemisinin-based combinations
Current Opinion in Infectious Diseases, 2005 Artemisinin-based combination treatments have been the mainstay of treatment for falciparum malaria in Southeast Asia for more than 10 years and are now increasingly recommended as first-line treatment throughout the rest of the world.A large multicentre randomised trial conducted in East Asia has shown a 35% reduction in mortality from severe malaria ...
Ashley, E, White, N
openaire +3 more sources
Molecular Markers of Antimalarial Drug Resistance in Plasmodium falciparum From Kumasi, Ghana, 2023
Tropical Medicine &International Health, EarlyView.ABSTRACT Objectives Artemisinin partial resistance has emerged in East Africa and is feared to spread across the continent, potentially compromising artemisinin‐based combination treatment. Molecular markers can serve as early warning signals for the development of specific drug resistance.
Albert Dennis Kegya +10 more
wiley +1 more source
Acyclic Nucleoside Phosphonates As Potential Inhibitors of Plasmodium Falciparum Egress
Chemistry – A European Journal, Volume 31, Issue 69, December 9, 2025.Exploration of the chemistry of acyclic nucleoside phosphonates allowed us to study structural diversity from the hit compound; biological evaluation and molecular docking were performed to decipher key interactions with the putative target. Abstract The emergence of drug‐resistant Plasmodium strains requires the development of novel antimalarial ...
Thomas Cheviet +6 more
wiley +1 more source
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994 The compounds derived from the Chinese medicinal plant qinghao (Artemisia annua) are the most rapidly acting of all antimalarial drugs. They are effective when given parenterally, orally or by suppository. No serious adverse effect has yet been reported in humans.
openaire +2 more sources
Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions
Advanced Science, Volume 12, Issue 46, December 11, 2025.Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley +1 more source
Systematic and Model-Assisted Process Design for the Extraction and Purification of Artemisinin from Artemisia annua L.—Part II: Model-Based Design of Agitated and Packed Columns for Multistage Extraction and Scrubbing [PDF]
, 2018 A. Schmidt +4 more
openalex +1 more source