Results 151 to 160 of about 74,638 (327)

Transferrin Receptor‐1: Expression in Canine Mammary Tumours and In Vitro Therapeutic Applications

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT The transferrin receptor‐1 (TFR‐1) is overexpressed in many types of human cancers and, in recent years, several studies have investigated its use as a preferential channel for drug cellular uptake in cancer therapy. In veterinary medicine, TFR‐1 expression in cancer cells and tissues has been poorly described, as well as its therapeutic ...
Valentina Moccia, Nicolò Rensi, Giovanni Paolo Marullo, Alessandro Sammarco, Federico Bonsembiante, Filippo Torrigiani, Lucia Salvioni, Davide Prosperi, Valentina Zappulli, Laura Cavicchioli   +9 more
wiley   +1 more source

Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia. [PDF]

, 2005
In the Maheba Refugee Settlement, in the clinics supported by Medecins Sans Frontieres, all children aged up to 5 years with a confirmed diagnosis of uncomplicated falciparum malaria are treated with the combination of sulfadoxine/pyrimethamine (SP) and ...
Bloland PB, Contamin H, National Malaria Control Centre, Nosten F, Peterson DS, Trape JF, Vasconcelos KF, White NJ, World Health Organisation (WHO), World Health Organisation (WHO)   +9 more
core   +2 more sources

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

British Journal of Pharmacology, Volume 182, Issue 15, Page 3411-3427, August 2025.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou, Guoming Li, Ruixiang Tan, Guodong Wu, Changsheng Deng   +4 more
wiley   +1 more source

Appraising the visibility, relevance and impacts of clinical pharmacology

British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1884-1898, July 2025.
Aims Clinical pharmacology (CP) used to be a strong medical and scientific field, but during the last three decades it seems to have lost some of its appeal. We reviewed the visibility, relevance and impact of CP and clinical pharmacologists across the globe and suggest ways to strengthen the discipline to address future pharmacotherapeutic challenges.
Serge Cremers, Samuel L. M. Arnold, Nilima A. Kshirsagar, Catriona Waitt, Olayinka O. Ogunleye, Lars L. Gustafsson   +5 more
wiley   +1 more source

A Randomized Double‐Blind, Placebo‐Controlled Trial of Artesunate and Curcumin in Patients With Crohn's Disease: A Pilot Study

JGH Open, Volume 9, Issue 7, July 2025.
ABSTRACT Aim Less than half of all patients with Crohn's disease remain in remission with long‐term use of azathioprine. Our aim was to assess the efficacy of Artesunate and Curcumin in maintaining remission in patients with Crohn's disease, who had ongoing evidence of disease activity despite taking azathioprine.
Devinder Kumar, Uday C Ghoshal, Vamika Mansi Saigal, Moni Chaudhary, Shikha Sahu, Vishruti Pandya, Ujjala Ghoshal   +6 more
wiley   +1 more source

In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii [PDF]

, 1994
Ellen Holfels, James McAuley, Douglas G. Mack, Wilbur K. Milhous, Rima McLeod   +4 more
openalex   +1 more source

AaABF3, an Abscisic Acid–Responsive Transcription Factor, Positively Regulates Artemisinin Biosynthesis in Artemisia annua

Frontiers in Plant Science, 2018
Artemisinin is well known for its irreplaceable curative effect on the devastating parasitic disease, Malaria. This sesquiterpenoid is specifically produced in Chinese traditional herbal plant Artemisia annua. Earlier studies have shown that phytohormone
Yijun Zhong, Ling Li, Xiaolong Hao, Xueqing Fu, Yanan Ma, Lihui Xie, Qian Shen, Sadaf Kayani, Qifang Pan, Xiaofen Sun, Kexuan Tang   +10 more
doaj   +1 more source

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Human Health and Diseases

MedComm, Volume 6, Issue 7, July 2025.
MAM dysfunction is considered as an initiator or contributor in the progression of various diseases such as nervous system diseases, circulatory system diseases, digestive system diseases, locomotor system diseases, reproductive system diseases, endocrine system diseases, urinary system diseases, respiratory system diseases and cancer.
Yong Liu, Zi‐Hui Mao, Junwen Huang, Hui Wang, Xiao Zhang, Xin Zhou, Yue Xu, Shaokang Pan, Dongwei Liu, Zhangsuo Liu, Qi Feng   +10 more
wiley   +1 more source

Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy [PDF]

, 1996
Steven R. Meshnick, Terrie E. Taylor, Sumalee Kamchonwongpaisan   +2 more
openalex   +1 more source

Role of LEAFLESS, an AP2/ERF family transcription factor, in the regulation of trichome specialized metabolism

New Phytologist, Volume 247, Issue 2, Page 774-790, July 2025.
Summary Acylsugars, specialized metabolites produced by trichomes of many solanaceous species, provide protection against biotic and abiotic stresses. Many acylsugar metabolic enzymes have been identified; however, regulatory factors remain unknown.
Sabyasachi Mandal, Yohannes H. Rezenom, Thomas D. McKnight   +2 more
wiley   +1 more source