Results 101 to 110 of about 8,416 (212)
eFood, Volume 7, Issue 1, February 2026.From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley +1 more source
How to tackle antimalarial resistance?
EMBO Molecular Medicine, 2016 Graphical Abstract In the context of drug resistance, malaria is no exception. Even the latest artemisinins have started to lose their full efficacy in patients.
Didier Leroy
doaj +1 more source
Elimination of Schistosoma mansoni in infected mice by slow release of artemisone
International Journal for Parasitology: Drugs and Drug Resistance, 2017 The current treatment of schistosomiasis is based on the anti-helminthic drug praziquantel (PZQ). PZQ affects only the adult stages of schistosomes. In addition, resistance to PZQ is emerging.
Daniel Gold +10 more
doaj +1 more source
Production and characterization of different types of malaria pigment (hemozoin) and their potential use for screening for hemozoin inhibiting drugs [PDF]
, 2012 Tese de mestrado. Biologia (Microbiologia Aplicada). Universidade de Lisboa, Faculdade de Ciências, 2012Malarial pigment, hemozoin, appears to modulate the immune system, however it remains controversial if it has stimulatory or inhibitory effects ...
Góis, Ana Margarida Ferreira, 1988-
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Transactions of the Royal Society of Tropical Medicine and Hygiene, 1994 The compounds derived from the Chinese medicinal plant qinghao (Artemisia annua) are the most rapidly acting of all antimalarial drugs. They are effective when given parenterally, orally or by suppository. No serious adverse effect has yet been reported in humans.
openaire +2 more sources
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
The synthetic peroxide OZ78 is effective against Echinostoma caproni and Fasciola hepatica [PDF]
, 2017 Objectives: The trematocidal properties of a synthetic peroxide, 1,2,4-trioxolane (OZ78) were determined both in vivo and in vitro. Methods: Two weeks post-infection Echinostoma caproni-infected mice were administered single oral doses of 400-1000 mg/kg ...
Dong, Yuxiang +4 more
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The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification
Advanced Science, Volume 13, Issue 4, 19 January 2026.Plant trichomes are not just simple hairs but metabolic powerhouses shaped by complex genetic programs. While the MYB‐bHLH‐WD40 module is well studied in Arabidopsis, recent findings reveal that HD‐Zip IV transcription factors drive multicellular and glandular trichome development through dose‐dependent mechanisms.
Meng Li +3 more
wiley +1 more source
Advanced Science, Volume 13, Issue 2, 9 January 2026.Genome‐scale metabolic modeling is preceded to the engineered E. coli cell factory for the de novo biosynthesis of biopesticide chrysanthemic acid. The debranching strategy redirects metabolic flux, enhancing precursor and target compound production.
Jiangpeng Yu +6 more
wiley +1 more source
Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase
Advanced Science, Volume 13, Issue 4, 19 January 2026.Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song +9 more
wiley +1 more source