Results 81 to 90 of about 6,373 (213)
Elimination of Schistosoma mansoni in infected mice by slow release of artemisone
International Journal for Parasitology: Drugs and Drug Resistance, 2017 The current treatment of schistosomiasis is based on the anti-helminthic drug praziquantel (PZQ). PZQ affects only the adult stages of schistosomes. In addition, resistance to PZQ is emerging.
Daniel Gold +10 more
doaj +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
Plant, Cell &Environment, EarlyView.ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Artemisinins: Mechanisms of action and potential for resistance. Drug Resist.
, 2004 Artemisinins form the most important class of antimalarial currently available, particularly because they are effective against parasites resistant to almost all the other classes. Their mechanism of action is controversial.
Sanjeev Krishna +2 more
core
, 2016 *McGready 2001 reported multiple types of artemisinin exposures that were combined for this analysis (12). ART artemisinins, AL artemether-lumefantrine, AS-SP artesunate sulfadoxine pyrimethamine, SP sulfadoxine pyrimethamine, No exp.
Richard Steketee (75064) +8 more
core +1 more source
Artemisinin antimalarials: preserving the "magic bullet" [PDF]
, 2010 The artemisinins are the most effective antimalarial drugs known. They possess a remarkably wide therapeutic index. These agents have been used in traditional Chinese herbal medicine for more then 2,000 years but were not subjected to scientific scrutiny
White, Lisa +9 more
core +1 more source
How to tackle antimalarial resistance?
EMBO Molecular Medicine, 2016 Graphical Abstract In the context of drug resistance, malaria is no exception. Even the latest artemisinins have started to lose their full efficacy in patients.
Didier Leroy
doaj +1 more source
Analytical Science Advances, Volume 7, Issue 2, December 2026.The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia +10 more
wiley +1 more source
The International Journal of Health Planning and Management, Volume 41, Issue 6, Page 1381-1393, December 2026.ABSTRACT Background and need As the WHO Global Traditional Medicine Strategy 2025–2034 encourages countries to consider integrating traditional, complementary and integrative medicine (TCIM) into health systems, there is a need to clarify the principal scientific, regulatory, ethical, and governance challenges involved. Renewed global attention to TCIM,
Abdul‐Basit Abdul‐Samed +3 more
wiley +1 more source
Plasmodium falciparum: multifaceted resistance to artemisinins [PDF]
, 2016 International audienceAbstractPlasmodium falciparum resistance to artemisinins, the most potent and fastest acting anti-malarials, threatens malaria elimination strategies.
Benoit-Vical, Françoise +14 more
core +1 more source
Plant, Cell &Environment, Volume 49, Issue 12, Page 9524-9539, December 2026.ABSTRACT Sorghum anthracnose caused by Colletotrichum sublineola (C. sublineola) is a destructive disease leading to severe crop damages. Pterostilbene is a phytoalexin that contributes to defence responses in sorghum, but the transcriptional regulation of its biosynthesis remained poorly understood.
Yajing Li +5 more
wiley +1 more source