Results 111 to 120 of about 17,496 (173)

Expression of mannanase and glucanases in lettuce chloroplasts and functional evaluation of enzyme cocktail against Candida albicans in oral cancer patient samples

open access: yesPlant Biotechnology Journal, Volume 23, Issue 7, Page 2689-2703, July 2025.
Transplastomic expression of mannanase in lettuce and tobacco chloroplasts and inhibition of Candida albicans from oral cancer patient samples by plant enzyme cocktail. Summary Candida albicans is a human pathogen responsible for several diseases. C. albicans cell wall contains chitin, glucan and mannan.
Iqra Fatima   +2 more
wiley   +1 more source

The synthetic peroxide OZ78 is effective against Echinostoma caproni and Fasciola hepatica [PDF]

open access: yes, 2017
Objectives: The trematocidal properties of a synthetic peroxide, 1,2,4-trioxolane (OZ78) were determined both in vivo and in vitro. Methods: Two weeks post-infection Echinostoma caproni-infected mice were administered single oral doses of 400-1000 mg/kg ...
Dong, Yuxiang   +4 more
core  

Artemisinin: large community studies

open access: yesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994
Prospective randomized trials with oral artemisinin derivatives have been conducted in over 1000 patients to determine the optimum treatment of multi-drug resistant falciparum malaria on the Thai-Burmese border. These drugs have proved valuable in 3 settings.
openaire   +3 more sources

Breeding triple‐advantage cottonseed with higher yield, enhanced nutrition, and reduced toxicity by redirecting terpenoid metabolism to astaxanthin

open access: yesPlant Biotechnology Journal, Volume 23, Issue 7, Page 2839-2851, July 2025.
Summary Cottonseed is a valuable source of edible oil and protein, but its utilization is limited by high gossypol content. In this study, we engineered cotton (Gossypium hirsutum) to biosynthesize astaxanthin through both single‐gene (CrBKT) and multi‐gene (CrBKT, ZmPSY1, PaCrtI, HpCrtZ) expression strategies.
Lu Long   +13 more
wiley   +1 more source

Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica [PDF]

open access: yes, 2017
Triclabendazole is the drug of choice against Fasciola hepatica infections in humans and animals. However, parasite resistance against triclabendazole is spreading in the veterinary field, and there are no drugs of comparable activity currently available
Brennan, Gerry   +5 more
core  

Efficacy and safety of artemether against a natural Fasciola hepatica infection in sheep [PDF]

open access: yes, 2018
Triclabendazole is the current drug of choice against Fasciola spp. infections in livestock, but resistance has become a major problem. In this study, we assessed the efficacy and safety of artemether, a derivative of artemisinin, in sheep with a low ...
Cringoli, Giuseppe   +6 more
core  

Efficacy and Tolerability of Antimalarials and Molecular Resistance Markers of Falciparum Malaria in Jimma Region, Ethiopia [PDF]

open access: yes, 2011
Due to increasing drug resistance, artemisinin-based combination chemotherapy (ACT) has become the first-line treatment of falciparum malaria in many endemic countries.
Eshetu, Teferi
core  

Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica [PDF]

open access: yes, 2017
Adult Fasciola hepatica were incubated for 48 h in vitro in the synthetic peroxide, OZ78 at a concentration of 100 μg/ml and then prepared for scanning and transmission electron microscopy. There was limited disruption to the external fluke surface, with
BRENNAN, G. P.   +4 more
core  

Artemisinin resistance in Myanmar [PDF]

open access: yesThe Lancet Infectious Diseases, 2015
Pascal Ringwald, Christopher V. Plowe
openaire   +3 more sources

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