Results 81 to 90 of about 17,496 (173)
Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission [PDF]
, 2012 <p>Background: Artemisinin-based combination therapy (ACT) for treating malaria has activity against immature gametocytes. In theory, this property may complement the effect of terminating otherwise lengthy malaria infections and reducing the ...
Abdulla, S.K. +10 more
core +6 more sources
Phenylethanoid Glycosides in Cistanches: Chemistry, Pharmacokinetic, and Antitumor Properties
Food Frontiers, EarlyView.This review systematically summarizes the representative PhGs found in CH species, their pharmacokinetic parameters, and primary metabolites in humans and rats. Additionally, it examines the antitumor activities of PhGs in CH and their associated signaling pathways against various malignancies.
Jie Li +7 more
wiley +1 more source
Two distinct and competitive pathways confer the cellcidal actions of artemisinins
Microbial Cell, 2015 The biological actions of artemisinin (ART), an antimalarial drug derived from Artemisia annua, remain poorly understood and controversial. Besides potent antimalarial activity, some of artemisinin derivatives (together with artemisinin, hereafter ...
Chen Sun +4 more
semanticscholar +1 more source
Interdisciplinary Medicine, EarlyView.Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang +12 more
wiley +1 more source
Blood, 2014 Patients with severe malaria treated with artesunate sometimes experience a delayed hemolytic episode. Artesunate (AS) induces pitting, a splenic process whereby dead parasites are expelled from their host erythrocytes.
S. Jauréguiberry +19 more
semanticscholar +1 more source
Imported falciparum malaria among adults requiring intensive care: analysis of the literature. [PDF]
, 2014 BACKGROUND: Malaria is the most important imported tropical disease. Infection with Plasmodium falciparum is responsible for most of the morbidity and mortality.
Armstrong, Margaret +3 more
core +3 more sources
Interdisciplinary Medicine, EarlyView.This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao +6 more
wiley +1 more source
Artesunate and artemether are effective fasciolicides in the rat model and in vitro [PDF]
, 2017 Objectives: To study the fasciocidal properties of artesunate and artemether in the rat model and in vitro. Methods: Adult Fasciola hepatica were exposed in vitro to 1, 10 and 100 µg/mL of artesunate, artemether and dihydroartemisinin for 72 h.
Keiser, Jennifer +3 more
core
Delayed haemolysis after artesunate therapy in a cohort of patients with severe imported malaria due to Plasmodium falciparum [PDF]
, 2016 INTRODUCTION: Delayed haemolytic anaemia is one of the more frequent events after treatment with intravenous artesunate in patients with severe malaria.
Calvo-Cano, Antonia +4 more
core +1 more source