Results 91 to 100 of about 28,412 (248)

Application of high⁃resolution magnetic resonance imaging vascular wall imaging in endovascular recanalization of chronic internal carotid artery occlusion

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To explore the application value of high⁃resolution magnetic resonance imaging vascular wall imaging (HR⁃VWI) in endovascular recanalization of chronic internal carotid artery occlusion (CICAO).
Yan-wei HOU   +9 more
doaj  

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

Endovascular treatment of acute ischemic stroke with large vessel occlusion: history, present and future

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Five randomized control clinical trials of N Engl J Med showed the efficacy of endovascular treatment (EVT) of acute ischemic stroke with large vessel occlusion (AIS ⁃ LVO) of anterior circulation. The "spring" of mechanical thrombectomy is coming.
Zhong⁃rong MIAO, HUO Xiao⁃chuan
doaj  

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

open access: yesAdvanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou   +16 more
wiley   +1 more source

Post-COVID-19 tibial and fibular arterial thrombosis: therapeutic approaches

open access: yesABCS Health Sciences
Introduction: Current evidence suggests that hypercoagulability may be a sequel to hyperinflammation, a key pathogenic mechanism that contributes to increased mortality in COVID-19.
Henrique Amorim Santos   +4 more
doaj   +1 more source

Targeting the Mapk13‐Tcf1‐Slc7a5 Axis via One‐Carbon Metabolic Regulation to Prevent Chronic Allograft Vasculopathy

open access: yesAdvanced Science, EarlyView.
This study emphasizes the role of the Mapk13‐Tcf1‐Slc7a5‐methionine metabolism axis in stem‐like CD4+ T cells. Moreover, it uncovers the mechanism through which limiting one‐carbon metabolism in CD4+ stem‐like T cells suppresses the tide of chronic allograft vasculopathy, offering potential targets to promote long‐term graft survival.
Wang Yi   +8 more
wiley   +1 more source

Remote Activation of Spinal TRPV1 by Magnetic Nanocubes Confers Cardioprotection Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Fe‐based magnetic nanocubes conjugated with TRPV1 antibodies (FeNCs‐TRPV1) are developed for the specific targeting of TRPV1 channels. Intraspinally injected FeNCs‐TRPV1 induces TRPV1 desensitization in rats exposed to repetitive and transient ACMF.
Xueying Cheng   +15 more
wiley   +1 more source

Intraoperative Evaluation of Bladder Perfusion Using Indocyanine Green Fluorescence Imaging During Total Pelvic Exenteration After Interruption of Blood Flow From the Internal Iliac Vessels

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Intraoperative ICG fluorescence imaging demonstrated that bladder perfusion was maintained through blood flow from the pubic side, even after complete division of the internal iliac vessels during total pelvic exenteration. ABSTRACT Background In lateral lymph node dissection (LLND) for locally advanced or recurrent rectal cancer, concomitant resection
Mamoru Uemura   +14 more
wiley   +1 more source

Proposal of Early Drain Exchange After Pancreatoduodenectomy From the View of Reducing Postoperative Pancreatic Fistula

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background To mitigate the progression of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD), appropriate drain management is required, and exchanging drainage tubes is commonly performed. However, the optimal timing of the first drain exchange has not yet been determined.
Taihei Soma   +7 more
wiley   +1 more source

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