Results 111 to 120 of about 13,023 (262)

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

Experimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

Experimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

Lower cerebral blood flow but not cerebrovascular response in elastin haploinsufficient mice

Experimental Physiology, EarlyView.
Abstract Elastin insufficiency is associated with structural differences in the large elastic arteries and cerebral artery dysfunction. However, previous studies have not assessed potential sex differences in cerebrovascular function. We measured cerebral blood flow (CBF) using arterial spin labeling MRI at rest and in response to hypercapnia challenge
Abigail E. Cullen, Emily H. Reeve, Nick R. Winder, Grant D. Henson, Nayantara Arora, Thomas Leonhardt, Ainsley Hogan, Sahana Krishna Kumaran, Naly Setthavonsack, Victoria Krajbich, Art Riddle, Benjamin Zimmerman, Nabil J. Alkayed, Martin M. Pike, Randall L. Woltjer, Ashley E. Walker   +15 more
wiley   +1 more source

A CSF Background Suppression Scheme in Arterial Spin Labeling MRI. [PDF]

NMR Biomed
Hu Z, Shi W, Gou Y, Wang Z, Yedavalli VS, Lin DD, Lu H.   +6 more
europepmc   +1 more source

Cerebrovascular regulation during heat stress

Experimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Giant serpentine aneurysm: Imaging features including potential diagnostic utility of arterial spin labeling. [PDF]

Radiol Case Rep
Martin JW, Fotouhi M, Fallahian AH, Fujii T, Russin J, Go JL, Assadsangabi R.   +6 more
europepmc   +1 more source

Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training

Experimental Physiology, EarlyView.
Abstract Advanced age is the strongest risk factor for Alzheimer's disease and related dementias (ADRDs). Traumatic brain injury (TBI) has also been recognized as a risk factor for ADRD, potentially contributing to an earlier onset of the disease. Thus, elucidating the mechanisms underlying brain ageing and TBI is critical for developing strategies to ...
Tsubasa Tomoto, Kan Ding, C. Munro Cullum, Rong Zhang   +3 more
wiley   +1 more source

Perfusion changes associated with intratumoral embolization and feeder occlusion for meningiomas: an arterial spin labeling study. [PDF]

Acta Neurochir (Wien)
Fukumura M, Kashiwagi H, Yoshimura K, Kosaka T, Fukuo Y, Takai S, Tsuji Y, Omura N, Futamura G, Yagi R, Hiramatsu R, Kameda M, Nonoguchi N, Furuse M, Kawabata S, Takami T, Wanibuchi M.   +16 more
europepmc   +1 more source

Effect of a single exercise bout on fasting cerebral blood flow and brain insulin sensitivity in middle‐aged to older adults

Experimental Physiology, EarlyView.
Abstract Reductions in brain insulin sensitivity and cerebral blood flow (CBF) have emerged as potential factors contributing to Alzheimer's disease and related dementia. However, no work has tested whether a single bout of exercise can raise brain insulin sensitivity in at‐risk adults. The aim of the study was to test whether a single bout of exercise
Steven K. Malin, Ankit M. Shah, Michal S. Berri, David H. Zald, Daniel J. Battillo   +4 more
wiley   +1 more source

Perfusion Territory Shifts in Cerebrovascular Diseases Measured by Super-Selective Arterial Spin Labeling. [PDF]

J Neuroimaging
Hoffmann G, Reichert M, Göttler J, Helle M, Schmitzer L, Petzsche MH, Zimmer C, Preibisch C, Kallmayer M, Kreiser K, Sollmann N, Liebl H, Kaczmarz S.   +12 more
europepmc   +1 more source