Results 191 to 200 of about 13,023 (262)

Dehydration-associated cerebral hypoperfusion in sudden sensorineural hearing loss: an arterial spin labeling-based preliminary study. [PDF]

open access: yesFront Neurol
Shrestha P   +9 more
europepmc   +1 more source

Podocyte‐Derived Extracellular Vesicles Induce Endothelial Dysfunction by Triggering ER Stress in Glomerular Disease

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Podocyte injury and endothelial cell dysfunction are the hallmarks of glomerular disease. How these two events are connected remains largely unknown. This study aimed to delineate the role of extracellular vesicles (EVs) in mediating podocyte‐endothelial communication in glomerular disease.
Zhao Liu   +10 more
wiley   +1 more source

Cerebral blood flow adaptations following 90 days head-down bed rest: Evidence from pseudo-continuous arterial spin labeling magnetic resonance imaging. [PDF]

open access: yesJ Cereb Blood Flow Metab
Liu Y   +12 more
europepmc   +1 more source

Acute Neurological Complications After Transplantation in Methylmalonic Acidemia: A 35‐Patient French Cohort

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Transplantation is an effective therapeutic option to improve quality of life in patients with severe methylmalonic acidemia (MMA). However, data regarding neurological complications following transplantation remain limited. A retrospective, single‐center study was conducted at Necker Hospital (France), including MMA patients who underwent ...
Adélaïde Vissac   +25 more
wiley   +1 more source

Role of Pseudo-Continuous Arterial Spin Labeling and 4D MR Angiography in the Diagnosis of Neck Paragangliomas. [PDF]

open access: yesJ Clin Med
Romano A   +11 more
europepmc   +1 more source

Downregulating Platelet Endothelial Cell Adhesion Molecule‐1 Enhances Learning and Memory and Alleviates Hallmark Pathologies in Alzheimer's Disease

open access: yesMedComm, Volume 7, Issue 3, March 2026.
CD31 upregulation in 5xFAD mice activates STAT1/Irf1 signaling, driving abnormal gene transcription, Aβ and tau accumulation, microglial activation, and neuroinflammation, leading to cognitive decline. Systemic CD31 knockdown suppresses STAT1/Irf1 activity, restores gene expression balance, reduces Aβ and tau pathologies, alleviates neuroinflammation ...
Qiuzhi Zhou   +17 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Gadolinium Pollution—A Future Forward Perspective on Human and Environmental Impact

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 3, Page 1660-1670, March 2026.
ABSTRACT The widespread use of gadolinium‐based contrast agents (GBCAs) in magnetic resonance imaging (MRI) has been instrumental in enhancing diagnostic capabilities. However, the potential environmental and human health impacts of gadolinium pollution have become a growing concern.
Makayla R. Long   +5 more
wiley   +1 more source

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