Multimodal MRI showed reduced global CBF‐ALFF coupling and increased medial prefrontal CBF/ALFF ratios in multiple sclerosis. The mPFC abnormality was associated with lower cognitive performance and greater disability. ABSTRACT Background Cognitive impairment is a prevalent and debilitating feature in multiple sclerosis (MS), yet its pathophysiology ...
Ruisi Gong +10 more
wiley +1 more source
Objectives We present the novel application of continuous arterial spin- labeling (CASL) magnetic resonance imaging ( MRI) for the measurement of calf muscle perfusion in subjects with progressive peripheral arterial disease (PAD).
吳文超, WU, WEN-CHAU
core
A Technical Perspective for Understanding Quantitative Arterial Spin-Labeling MR Imaging Using Continuous ASL [PDF]
The current paper describes visually the system of CBF measurement by continuous ASL using schematic illustration. I also discussed the effects of the parameters used in continuous ASL to CBF values as measured with ASL-MRI.
openaire +2 more sources
The long and winding road to translation for imaging biomarker development: the case for arterial spin labelling (ASL) [PDF]
Radiology is facing many challenges nowadays, and certainly needs to keep up with the fast pace of developments taking place in this field. This editorial aims at drawing the attention of the reader to the current establishment of quantitative imaging biomarkers, in particular through the efforts of the Quantitative Imaging Biomarker Alliance (QIBA ...
openaire +3 more sources
DynaTOF: Time‐Resolved Noncontrast Cerebral MR Angiography Using Spatially Modulated RF Saturation
ABSTRACT Purpose To develop a time‐resolved extension of three‐dimensional time‐of‐flight MR angiography, termed Dynamic TOF (DynaTOF), that exploits intrinsic RF saturation behavior to enable noncontrast visualization of cerebrovascular hemodynamics.
Naoyuki Takei +9 more
wiley +1 more source
Regional and depth-dependence of cortical blood-flow assessed with high-resolution Arterial Spin Labeling (ASL). [PDF]
Taso M, Munsch F, Zhao L, Alsop DC.
europepmc +1 more source
Renal Arterial Spin Labeling Magnetic Resonance Imaging.
Arterial spin labeling (ASL) MRI allows the quantification of tissue perfusion without administration of exogenous contrast agents. Patients with reduced renal function or other contraindications to Gadolinium-based contrast media may benefit from the ...
Becker AS, Rossi C
core +1 more source
Relationship between Cerebral Perfusion on Arterial Spin Labeling (ASL) MRI with Brain Volumetry and Cognitive Performance in Mild Cognitive Impairment and Dementia due to Alzheimer's Disease. [PDF]
Soman S +8 more
europepmc +1 more source
Oxygenaging: A Physiological Framework for Geroscience
Mechanisms of aging disrupt oxygen homeostasis through three converging processes: oxygen‐cascade impairment, microvascular dysfunction, and molecular maladaptation. “Oxygenaging” integrates these domains to explain how declining oxygen delivery and utilization drive mitochondrial instability and amplify the effect of the hallmarks of aging.
Stefano Donega +6 more
wiley +1 more source
In the context of the Horizon Europe EBRAINS 2.0 research consortium, Delphi‐derived, consented protocol recommendations from European Academy of Neurology Scientific Panel experts provide a pragmatic framework for harmonizing multi‐scale data acquisition for connectome analyses in stroke, Parkinson's Disease, and glioma.
Thomas Berger +17 more
wiley +1 more source

