Results 41 to 50 of about 725,720 (244)

Neoaortic Bicuspid Valve Replacement in Patient After Arterial Switch Operation to Correct Dextro-Transposition of the Great Arteries

open access: yesНеотложная медицинская помощь, 2023
INTRODUCTION Transposition of the great arteries is the second most common cyanotic congenital heart defect after tetralogy of Fallot. The arterial switch procedure (А. Jatene, 1975) is the surgical treatment of choice.
V. S. Selyaev   +6 more
doaj   +1 more source

“Bendy” stents help negotiate hairpin intracardiac curves [PDF]

open access: yes, 2015
Simple transposition of the great arteries (TGA) occurs in 0.2 per 1000 live births. The condition is surgically repaired in the neonatal period by the arterial switch procedure (ASO) sometimes preceded by an atrial septostomy.
Bugeja, Justine   +2 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Functional outcomes after neonatal open cardiac surgery: comparison of survivors of the Norwood staged procedure and the arterial switch operation

open access: yes, 2010
Background: Improvements in long-term survival of children undergoing the Norwood staged procedure and the arterial switch operation have resulted in the need to prepare these at-risk children for each stage of their developmental trajectory, including ...
Robertson, C.   +4 more
core   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Development of neoaortic pseu

open access: yesJournal of the Saudi Heart Association, 2016
We report a case of a 46-day-old boy who was diagnosed with transposition of the great arteries and underwent arterial switch operation. A large neoaortic pseudoaneurysm was diagnosed on the first postoperative follow up.
Abdullah A. Alghamdi   +1 more
doaj   +1 more source

Late Complications Following the Arterial Switch Operation

open access: yes, 2010
The arterial switch operation has been the principal treatment for transposition of the great arteries and its variants for the last 25 years. Early mortality has decreased significantly over time, but long-term complications include pulmonary artery ...
Constantine Mavroudis   +3 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Long-term surgical results of transposition of the great arteries with left ventricular outflow tract obstruction

open access: yesJournal of Cardiothoracic Surgery, 2022
Objective The objective of this study was to evaluate the long-term surgical results of transposition of the great arteries with left ventricular outflow tract obstruction.
Akihisa Furuta   +4 more
doaj   +1 more source

Hypoxia due to unusual right to left shunt after arterial switch surgery

open access: yesAnnals of Cardiac Anaesthesia, 2021
Hypoxia can occur after repair of transposition of great arteries. The most common cause of right to left shunt after arterial switch surgery is related to increased right ventricular pressures and persistent neonatal pulmonary arterial hypertension.
Suresh Rao Kemundel Genny   +3 more
doaj   +1 more source

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