Results 81 to 90 of about 65,617 (244)

Validation of a microRNA profile in urine liquid biopsy with diagnostic and stratification value for bladder cancer classification, available through the open app BladdermiRaCan

open access: yesExperimental Hematology & Oncology
We aimed to identify a profile of urine microRNAs (miRNAs) with diagnostic and stratification potential in the whole range of bladder cancer (BC) categories, to avoid current invasive, harmful and expensive procedures.
Julia Oto   +10 more
doaj   +1 more source

Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay

open access: yesJournal of Lipid Research, 2004
Acyl CoA:cholesterol acyltransferase 1 (ACAT1) and ACAT2 are enzymes responsible for the formation of cholesteryl esters in tissues. While both ACAT1 and ACAT2 are present in the liver and intestine, the cells containing either enzyme within these ...
Aaron T. Lada   +6 more
doaj   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

open access: yesBrain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle   +7 more
wiley   +1 more source

Medial calcific arteriosclerosis mimicking giant cell arteritis [PDF]

open access: yes, 2015
Introduction: Medial calcific arteriosclerosis is characterized by diffuse mineral deposition in the tunica media of arterial walls. First described in patients with diabetes mellitus, medial calcific arteriosclerosis has been increasingly recognized in ...
Kohen, Laurie L   +2 more
core  

Cholesterol and arteriosclerosis [PDF]

open access: yes, 2016
The endothelium, the layer of cells lining the interior of blood vessels, forms a complicated interface that uses signals carried by the circulating blood to modulate vascular tone, the concentration of inflammatory cells and the coagulation cascade.
openaire   +1 more source

Targeting PCSK9 in Vascular Smooth Muscle Cells: An Effective Strategy to Suppress Ferroptosis and Attenuate Abdominal Aortic Aneurysm Progression

open access: yesCell Proliferation, EarlyView.
PCSK9 aggravates AAA by promoting ferroptosis in VSMCs. In the pathological AAA environment, PCSK9 upregulation triggers ferritinophagy‐dependent degradation of FTH1, leading to Fe2+ release, triggering lipid peroxidation and ferroptosis, exacerbating AAA.
Mengdie Xia   +13 more
wiley   +1 more source

El metabolismo del colesterol y la arteriosclerosis [PDF]

open access: yes, 1996
Proceso degenerativo del sistema arterial, así denominado por los singulares estados finales que presenta la enfermedad, que conducen a la formación de depósitos calcáreos, estrechamiento y endurecimiento de los vasos.
Agudelo Cardona, Mauricio   +2 more
core  

Glucagon‐Like Peptide‐1 Receptor Agonists and Risk of Mental Health Disorders in Type 2 Diabetes: Active Comparator, New User Cohort Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims We evaluated the risk of mental health disorders among glucagon‐like peptide‐1 receptor agonist (GLP1RA) users compared with users of dipeptidyl peptidase‐4 (DPP‐4) inhibitors and sodium‐glucose cotransporter‐2 (SGLT2) inhibitors. Materials and Methods We conducted a nationwide, active‐comparator new‐user cohort study using the Korean ...
Chungsoo Kim   +5 more
wiley   +1 more source

Vitamin B6 and Arteriosclerosis [PDF]

open access: yes
In 1949, Rinehart and Greenberg reported that marked arteriosclerosis occurs in vitamin-B6-deficient monkeys. The present study investigates the relationship between vitamin B6 and arteriosclerosis and summarizes the results. I found that thrombogenesis,
KUZUYA, FUMIO
core  

EL METABOLISMO DEL COLESTEROL Y LA ARTERIOSCLEROSIS [PDF]

open access: yes, 2010
Proceso degenerativo del sistema arterial, así denominado por los singulares estados finales que presenta la enfermedad, que conducen a la formación de depósitos calcáreos, estrechamiento y endurecimiento de los vasos.
Agudelo Cardona, Mauricio   +2 more
core  

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