Results 11 to 20 of about 4,817 (146)

Audio-vestibular symptoms in systemic autoimmune diseases [PDF]

open access: yes, 2018
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce   +7 more
core   +1 more source

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

open access: yes, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter   +3 more
core   +1 more source

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

open access: yes, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal   +268 more
core   +1 more source

Opportunistic Infections in Patients with Temporal Arteritis Treated with Corticosteroids [PDF]

open access: yes, 1997
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111238/1/j.1532-5415.1997.tb00949.x ...
Bonilla, Hector F.   +3 more
core   +1 more source

Influence of the IL17A locus in giant cell arteritis susceptibility [PDF]

open access: yes, 2017
Objective: Different lines of evidence have highlighted the role of IL-17A in the inflammatory process occurring in giant cell arteritis (GCA). The aim of the present study was to assess whether the IL17A locus influences GCA susceptibility and its ...
Beretta, Lorenzo   +31 more
core   +1 more source

Design of the Tocilizumab in Giant Cell Arteritis Trial [PDF]

open access: yes, 2013
Overview. The GiACTA trial is a multicenter, randomized, double-blind, and placebo-controlled study designed to test the ability of tocilizumab (TCZ), an interleukin (IL)-6 receptor antagonist, to maintain disease remission in patients with giant cell ...
Dasgupta, Bhaskar   +8 more
core   +3 more sources

Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling [PDF]

open access: yes, 2014
International audienceIntroduction: Giant cell arteritis (GCA) is characterized by intimal hyperplasia leading to ischaemic manifestations that involve large vessels.
Alexis Régent   +15 more
core   +2 more sources

Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis [PDF]

open access: yes, 2018
Background: Giant-cell arteritis (GCA) is an inflammatory disease of large/medium-sized arteries, frequently involving the temporal arteries (TA). Inflammation-induced vascular remodelling leads to vaso-occlusive events. Circulating endothelin-1 (ET1) is
Alba, Marco A.   +11 more
core   +1 more source

A genome-wide association study identifies risk alleles in plasminogen and P4HA2 associated with giant cell arteritis [PDF]

open access: yes, 2016
Giant cell arteritis (GCA) is the most common form of vasculitis in individuals older than 50 years in Western countries. To shed light onto the genetic background influencing susceptibility for GCA, we performed a genome-wide association screening in a ...
Abdel Salih   +183 more
core   +11 more sources

The prevalence of giant cell arteritis and polymyalgia rheumatica in a UK primary care population [PDF]

open access: yes, 2016
Background: To update community-based prevalence values for Polymyalgia Rheumatic (PMR) and Giant Cell Arteritis (GCA) using case record review supplemented by population survey and subsequent clinical review.
A Mohammad   +30 more
core   +1 more source

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