Results 61 to 70 of about 2,485,134 (364)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Experimental study on coronary perfusion with selective brain cooling for direct aortic surgery [PDF]

, 1959
1. Retrograde coronary perfusion in combination with selective brain cooling by irrigation was investigated in dogs, in comparison with direct coronary artery perfusion. 2.
Hayashi, Naomi
core   +1 more source

Effect of Low-Density Lipoprotein Cholesterol Goal Achievement on Vascular Physiology Evaluated by Quantitative Flow Ratio in Patients Who Underwent Percutaneous Coronary Intervention

Frontiers in Cardiovascular Medicine, 2021
Purpose: The change in coronary physiology from lipid-lowering therapy (LLT) lacks an appropriate method of examination. Quantitative flow ratio (QFR) is a novel angiography-based approach allowing rapid assessment of coronary physiology.
Long Chen, Long Chen, Long Chen, Qin Chen, Qin Chen, Qin Chen, Jiaxin Zhong, Jiaxin Zhong, Jiaxin Zhong, Zhen Ye, Zhen Ye, Zhen Ye, Mingfang Ye, Mingfang Ye, Mingfang Ye, Yuanming Yan, Yuanming Yan, Yuanming Yan, Lianglong Chen, Lianglong Chen, Lianglong Chen, Yukun Luo, Yukun Luo, Yukun Luo   +23 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Long-term prognosis for individuals with hypertension undergoing coronary artery calcium scoring [PDF]

, 2015
To examine the performance of coronary artery calcification (CAC) for stratifying long-term risk of death in asymptomatic hypertensive ...
Callister, Tracy Q, Chang, Hyuk Jae, Cho, Iksung, Giambrone, Ashley E, Gransar, Heidi, Heo, Ran, Kalra, Dan K, Lin, Fay Y, Min, James K., Schulman Marcus, Joshua, Sciarretta, Sebastiano, Shaw, Leslee J, Truong, Quynh A, Valenti, Valentina, Ó. Hartaigh, Bríain   +14 more
core   +1 more source

Impact of Obstructive Sleep Apnea and Triglyceride Glucose Index on Cardiovascular Events in Acute Coronary Syndrome Patients: A Post-Hoc Analysis of the OSA–ACS Study

Reviews in Cardiovascular Medicine
Background: Obstructive sleep apnea (OSA) is highly prevalent in patients with acute coronary syndrome (ACS). The triglyceride glucose (TyG) index is considered closely linked to cardiovascular risk.
Yuekun Zhang, Ding Xu, Wen Zheng, Wen Hao, Lei Zhen, Yan Yan, Xiao Wang, Shaoping Nie   +7 more
doaj   +1 more source

A Chinese scoring system for predicting successful retrograde collateral traverse in patients with chronic total coronary occlusion

BMC Cardiovascular Disorders, 2023
Background Retrograde approach technique has been challenging in percutaneous coronary interventional treatment of chronic total occlusion (CTO) coronary disease.
Qiu Yu Li, Xiao Long Lin, Fan Qi Li, Zi Chao Cheng, Jia Yu Tian, Dong Hui Zhao, Wayne Bond Lau, Jing Hua Liu, Qian Fan   +8 more
doaj   +1 more source

Presence of Coronary Endothelial Dysfunction, Coronary Vasospasm, and Adenosine-Mediated Vasodilatory Disorders in Patients With Ischemia and Nonobstructive Coronary Arteries [PDF]

, 2022
Rutger G.T. Feenstra, Coen K.M. Boerhout, Janneke Woudstra, Caitlin E.M. Vink, Marianne E. Wittekoek, Guus A. de Waard, Yolande Appelman, Etto C. Eringa, Koen Marques, Robbert J. de Winter, Marcel A.M. Beijk, Tim P. van de Hoef, Jan J. Piek   +12 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source