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Background The use of tramadol among osteoarthritis (OA) patients has been increasing rapidly around the world, but population-based studies on its safety profile among OA patients are scarce.
Lingyi Li+7 more
doaj +1 more source
A Holistic Approach on Smart Garment for Patients with Juvenile Idiopathic Arthritis [PDF]
Juvenile Idiopathic Arthritis (JIA) is a widespread and chronic condition that affects children and adolescents worldwide. The person suffering from JIA is characterized by chronic joint inflammation leading to pain, swelling, stiffness, and limited body movements. Individuals suffering from JIA require ongoing treatment for their lifetime.
arxiv +1 more source
Background: Meniscus injuries, a common joint disease caused by long-term wear, trauma and inflammation, usually cause chronic dysfunction and pain in the joint.
Zhen Yang+12 more
doaj +1 more source
Objective We estimated the association between immunosuppressive and immunomodulatory agent (IIA) exposure and severe COVID‐19 outcomes in a population‐based cohort study.
Shelby Marozoff+14 more
doaj +1 more source
Objectives To assess the risk of severe COVID-19 outcomes in patients with autoimmune rheumatic diseases (ARDs) and transplant recipients compared with matched general population comparators.Design Population-based matched cohort study using ...
John Esdaile+7 more
doaj +1 more source
BackgroundMacrophages significantly contributes to symptomology and structural progression of osteoarthritis (OA) and raise increasing attention in the relative research field.
Zhen Yang+14 more
doaj +1 more source
Bridging disconnected networks of first and second lines of biologic therapies in rheumatoid arthritis with registry data: Bayesian evidence synthesis with target trial emulation [PDF]
Objective: We aim to utilise real world data in evidence synthesis to optimise an evidence base for the effectiveness of biologic therapies in rheumatoid arthritis in order to allow for evidence on first-line therapies to inform second-line effectiveness estimates.
arxiv +1 more source
The importance of early arthritis in patients with rheumatoid arthritis [PDF]
Rheumatoid arthritis (RA) is a systemic inflammatory disorder that manifests predominantly in the synovial joint, where it causes a chronic inflammatory process, leading to early osteoarticular destructions.
Diaconu, Camelia C+9 more
core +3 more sources
Background To estimate the prevalence of pain among people aged 45 years and older in China, to analyze the effect factors of pain and pain related economic burden.
Yudian Qiu+8 more
doaj +1 more source
Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis [PDF]
Introduction Chemokines and their receptors control immune cell migration during infections as well as in autoimmune responses. A 32 bp deletion in the gene of the chemokine receptor CCR5 confers protection against HIV infection, but has also been ...
Arnold, Sybille+6 more
core +2 more sources