Results 41 to 50 of about 1,005,051 (309)

The Immunology of Rheumatoid Arthritis

Nature Immunology, 2020
The immunopathogenesis of rheumatoid arthritis (RA) spans decades, beginning with the production of autoantibodies against post-translationally modified proteins (checkpoint 1).
C. Weyand, J. Goronzy
semanticscholar   +1 more source

Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

Nature Communications, 2020
Gut microbial dysbiosis is associated with the development of autoimmune disease, but the mechanisms by which microbial dysbiosis affects the transition from asymptomatic autoimmunity to inflammatory disease are incompletely characterized.
N. Tajik, M. Frech, Oscar Schulz, F. Schälter, S. Lucas, V. Azizov, K. Dürholz, Franziska Steffen, Y. Omata, A. Rings, M. Bertog, A. Rizzo, A. Iljazović, M. Basic, A. Kleyer, S. Culemann, G. Krönke, Yubin Luo, K. Überla, U. Gaipl, B. Frey, T. Strowig, K. Sarter, S. Bischoff, S. Wirtz, J. Cañete, Francesco Ciccia, G. Schett, M. Zaiss   +28 more
semanticscholar   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

The diagnosis and arthroscopic treatment of angioleiomyoma presenting loose body in the knee joint: two case reports

BMC Musculoskeletal Disorders, 2018
Background Angioleiomyoma is a very rare benign solitary soft tissue neoplasm originating from smooth muscle layer of blood vessels. The tumor is usually located in the subcutis or the superficial fasciae, but less often in the deep fasciae, especially ...
Chenxi Cao, Zhengming Cao, Guangyu Liu, Songyang Liu, Yanqi Ye, Tiezheng Sun   +5 more
doaj   +1 more source

Global research trends in extracellular vesicles based on stem cells from 1991 to 2021: A bibliometric and visualized study

Frontiers in Bioengineering and Biotechnology, 2022
Objective: With the development of extracellular vesicles (EVs) based on stem cells research all over the world, our present study was aiming to discover the global trends in this field.Methods: All publications related to EVs based on stem cells from ...
Jianjing Lin, Jianjing Lin, Jianjing Lin, Zhen Yang, Zhen Yang, Li Wang, Dan Xing, Dan Xing, Jianhao Lin, Jianhao Lin   +9 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Risk of venous thromboembolism in patients with rheumatoid arthritis: a meta-analysis of observational studies

BMC Rheumatology
Background Thrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thrombosis (DVT) and pulmonary embolism (
Zahra A Fazal, Ana Michelle Avina-Galindo, Shelby Marozoff, Jessie Kwan, Na Lu, J. Antonio Avina-Zubieta   +5 more
doaj   +1 more source

2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis

Arthritis care & research, 2016
To develop a new evidence‐based, pharmacologic treatment guideline for rheumatoid arthritis (RA).
J. Singh, K. Saag, S. L. Bridges, E. Akl, Raveendhara R. Bannuru, M. Sullivan, E. Vaysbrot, Christine McNaughton, M. Osani, R. Shmerling, J. Curtis, D. Furst, D. Parks, A. Kavanaugh, J. O'dell, Charles King, Amye Leong, E. Matteson, J. Schousboe, B. Drevlow, S. Ginsberg, J. Grober, E. St.clair, E. Tindall, Amy S. Miller, T. McAlindon   +25 more
semanticscholar   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source