Results 31 to 40 of about 827,161 (300)

24-hour activity and sleep profiles in arthritis

, 2020
Objectives: Identify 24-hour activity-sleep profiles in adults with arthritis and explore factors associated with profile membership. Methods: Cross-sectional cohort, using baseline data from two randomized trials studying activity counselling for ...
Feehan, Lynne M., Lynne M. Feehan, Na Lu, Lu, Na, Xie, Hue, Li, Linda C., Linda C. Li, Hui Xie   +7 more
core   +1 more source

Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]

, 2015
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
Kelly, S, Maria DiCicco, Hands, RE, Frances Humby, Riahi, S, Nora Ng, Michele Bombardieri, Arti Mahto, Sudeh Riahi, Humby, F, DiCicco, M, Rebecca E Hands, Marrelli, A, Pitzalis, C, Stephen Kelly, Pyne, D, Lu Zou, Bombardieri, M, Mahto, A, Ng, N, Costantino Pitzalis, Zou, L, Debasish Pyne, Alessandra Marrelli   +23 more
core   +1 more source

Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation

Stem Cells Translational Medicine, 2019
Patients with late‐stage Kellgren‐Lawrence knee osteoarthritis received a single intra‐articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM‐MSCs) in a phase I/IIa trial to assess safety and efficacy using a broad toolset ...
Jaskarndip Chahal, Alejandro Gómez‐Aristizábal, Konstantin Shestopaloff, Shashank Bhatt, Amélie Chaboureau, Antonietta Fazio, Jolene Chisholm, Amanda Weston, Julia Chiovitti, Armand Keating, Mohit Kapoor, Darrell J. Ogilvie‐Harris, Khalid A. Syed, Rajiv Gandhi, Nizar N. Mahomed, Kenneth W. Marshall, Marshall S. Sussman, Ali M. Naraghi, Sowmya Viswanathan   +18 more
doaj   +1 more source

Caloric restriction improves glycaemic control without reducing plasma branched-chain amino acids or keto-acids in obese men

Scientific Reports, 2022
Higher plasma leucine, isoleucine and valine (BCAA) concentrations are associated with diabetes, obesity and insulin resistance (IR). Here, we evaluated the effects of 6-weeks very-low calorie diet (VLCD) upon fasting BCAA in overweight (OW) non-diabetic
M. H. Sayda, M. H. Abdul Aziz, N. Gharahdaghi, D. J. Wilkinson, P. L. Greenhaff, B. E. Phillips, K. Smith, I. Idris, P. J. Atherton   +8 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The diagnosis and arthroscopic treatment of angioleiomyoma presenting loose body in the knee joint: two case reports

BMC Musculoskeletal Disorders, 2018
Background Angioleiomyoma is a very rare benign solitary soft tissue neoplasm originating from smooth muscle layer of blood vessels. The tumor is usually located in the subcutis or the superficial fasciae, but less often in the deep fasciae, especially ...
Chenxi Cao, Zhengming Cao, Guangyu Liu, Songyang Liu, Yanqi Ye, Tiezheng Sun   +5 more
doaj   +1 more source

Global research trends in extracellular vesicles based on stem cells from 1991 to 2021: A bibliometric and visualized study

Frontiers in Bioengineering and Biotechnology, 2022
Objective: With the development of extracellular vesicles (EVs) based on stem cells research all over the world, our present study was aiming to discover the global trends in this field.Methods: All publications related to EVs based on stem cells from ...
Jianjing Lin, Jianjing Lin, Jianjing Lin, Zhen Yang, Zhen Yang, Li Wang, Dan Xing, Dan Xing, Jianhao Lin, Jianhao Lin   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Risk of venous thromboembolism in patients with rheumatoid arthritis: a meta-analysis of observational studies

BMC Rheumatology
Background Thrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thrombosis (DVT) and pulmonary embolism (
Zahra A Fazal, Ana Michelle Avina-Galindo, Shelby Marozoff, Jessie Kwan, Na Lu, J. Antonio Avina-Zubieta   +5 more
doaj   +1 more source

Silicon, a Possible Link between Environmental Exposure and Autoimmune Diseases: The Case of Rheumatoid Arthritis [PDF]

, 2020
Silicon is one of the most common chemicals on earth. Several compounds such as silica, asbestos, silicone or, nanoparticles are built from tetrahedral units with silicon as the central atom.
Speck-Hernandez, Cesar A, Montoya-Ortiz, Gladis, Speck-Hernandez, Cesar A.   +2 more
core   +2 more sources