ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar +5 more
wiley +1 more source
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
Low ICU Admission and Excellent Outcomes in MIS‐C: A Swedish Study From an Open Society
ABSTRACT Aim During the COVID‐19 pandemic, Sweden chose a more open public health approach. A general concern was that this approach would affect the population negatively. We describe the Swedish national MIS‐C cohort and risk factors for severe disease defined as admission to the intensive care unit and cardiogenic shock.
Petra Król +13 more
wiley +1 more source
Abstract Objective The purpose of this article was to present a model for effective research alliances that facilitate collective action to advance scientific fields. The Parenting and Family Research Alliance (PAFRA) was used as an exemplar to illustrate its application.
Matthew R. Sanders +13 more
wiley +1 more source
Physical activity and quality of life of children and adolescents with juvenile idiopathic arthritis, juvenile systemic lupus erythematosus and juvenile dermatomyositis during the COVID-19 pandemic. [PDF]
Soares R +5 more
europepmc +1 more source
Welfare assessment of turkeys (Meleagris gallopavo gallopavo) on farm
Abstract This Scientific Opinion assesses the welfare of turkeys of all ages (Meleagris gallopavo gallopavo) on farm in relation to the type and condition of the litter, type and availability of enrichment (including covered veranda and outdoor range), space allowance, concentrations of ammonia and carbon dioxide, effective environmental temperature ...
EFSA Panel Animal Health and Animal Welfare (AHAW) +23 more
wiley +1 more source
Juvenile arthritis damage index predicts poor response to biological treatment: A prospective cohort study. [PDF]
Kolkhidova ZA +4 more
europepmc +1 more source
Juvenile rhupus syndrome: A case report of coexistence of JIA and SLE. [PDF]
Abedeen ZU +6 more
europepmc +1 more source
Use of biologic drugs in juvenile idiopathic arthritis patients followed in an adult rheumatology clinic: real-life data from the HUR-BIO biologic registry. [PDF]
Ata EB +15 more
europepmc +1 more source
Adoption of new treatment options in non-systemic juvenile idiopathic arthritis (JIA) in clinical practice. [PDF]
Lamers HC +6 more
europepmc +1 more source

