Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri+7 more
wiley +1 more source
Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan+115 more
core +1 more source
Objective We estimated the real‐world cost‐effectiveness of a standardized education and exercise therapy program (GLA:D) compared to usual care (UC) for people managing hip and/or knee osteoarthritis (HKOA). Methods We used a prospective matched cohort design to recruit people (aged >45 years) diagnosed with HKOA who used GLA:D or UC (not on a ...
Darren R. Mazzei+4 more
wiley +1 more source
Evolving clinical profile of IL-1β, IL-10 and CTLA-4 gene in rheumatoid factor positive Caucasian population [PDF]
Rheumatoid arthritis (RA), a systemic autoimmune condition, causes joint damage and sometimes extra-articular lesions (cutaneous vasculitis, neuropathy, Felty’s syndrome, pericarditis, intersticial lung disease) that may be life threatening.
Anupama Sharma, Ajay kumar Singh, Sanjeev kumar Singh, Neelima Singh, Varsha Gupta, Int J Cur Bio Med Sci.
core
Cost-effectiveness analysis of tocilizumab in combination with methotrexate for rheumatoid arthritis: A Markov model based on data from Serbia, country in socioeconomic transition [PDF]
Background/Aim. Recent studies have shown that biological treatments for rheumatoid arthritis can change the course of rheumatoid arthritis and improve functional ability of patients with rheumatoid arthritis.
Janković Slobodan M.+4 more
core +1 more source
Ageism in Rheumatology: The Health Care Professional's Perspective
Objective Ageism (age‐based stereotypes, prejudice, or discrimination) is prevalent and linked to prolonged disability and reduced lifespan in older adults. Little is known about ageism within rheumatology. This study explores the health care professional's (HCP) perception of the care of older adults and how ageist attitudes or perspectives may impact
Aaron P. Smith+4 more
wiley +1 more source
Objective Autoimmune rheumatic diseases commonly affect individuals of childbearing age, with historically increased adverse pregnancy outcomes in this group. The advent of disease‐modifying antirheumatic drugs (DMARDs) has fostered more suitable conditions for pregnancy; however, this is accompanied by challenges in ensuring safe use in reproductive ...
Athena Chin+4 more
wiley +1 more source
The Interrelation of Insulin Resistance, Serum Adiponectin Level inRheumatoid Arthritis Hypertensive Females with Subclinical Atherosclerosisand its Dynamics with the Endothelial Dysfunction Correction [PDF]
The study shows the results of comprehensive clinical and laboratory, instrumental, biochemical examination of 62 hypertensive females aged 45-65 years with rheumatoid arthritis, there were summarized data on the role of main and additional risk factors ...
Kuryata, O., Sirenko, O.
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Exosome application in treatment and diagnosis of B-cell disorders: leukemias, multiple sclerosis, and arthritis rheumatoid. [PDF]
Karami Fath M+10 more
europepmc +1 more source
Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and rheumatoid arthritis [PDF]
Acknowledgements The authors would like to thank Cynthia Fraser for helping run the literature search, Dr Neil Basu for providing advice on search terms for rheumatoid arthritis and to Xueli Jia, Katie Bannister and Kubra Boza for their help with foreign
Aucott, Lorna+4 more
core +3 more sources