Results 11 to 20 of about 299,635 (236)

Rheumatoid arthritis [PDF]

Inflammation and Regeneration, 2020
AbstractRheumatoid arthritis is an autoimmune inflammatory disease primarily characterized by synovitis which is accompanied by extra-articular organ involvement, such as interstitial pneumonia, in addition to clinical symptoms including pain, swelling, stiffness of multiple joints, fever, and malaise. Joint destruction progresses soon after the onset,
openaire   +3 more sources

Non-TNF inhibitor switchers versus TNF inhibitor cyclers from multicentre rheumatoid arthritis ultrasonography prospective cohort in Japan

Immunological Medicine, 2020
To compare therapeutic efficacy of tumour necrosis factor inhibitor (TNFi) cyclers and non-TNFi switchers in patients with rheumatoid arthritis (RA) having inadequate response to previous TNFis (TNF-IR patients) using composite measures including imaging
Yushiro Endo, Shin-ya Kawashiri, Shimpei Morimoto, Ayako Nishino, Momoko Okamoto, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Takashi Igawa, Tomohiro Koga, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Yukitaka Ueki, Tamami Yoshitama, Nobutaka Eiraku, Naoki Matsuoka, Akitomo Okada, Keita Fujikawa, Hiroaki Hamada, Tomomi Tsuru, Shuji Nagano, Yojiro Arinobu, Toshihiko Hidaka, Yoshifumi Tada, Atsushi Kawakami   +28 more
doaj   +1 more source

Clinical analyses of ultrasound-guided nerve block in lower-extremity surgery: A retrospective study

Journal of Orthopaedic Surgery, 2021
Purpose: The purpose of this study is to examine the clinical effects and results of lower-extremity surgery under ultrasound-guided nerve block; time required for nerve block, anesthesia onset time, duration of anesthesia, duration of analgesia ...
Chan Kang, Deuk-Soo Hwang, Jae-Hwang Song, Gi-Soo Lee, Jeong-Kil Lee, Sung-Jin Hwang, Je-Hyung Jeon, Byung-Kuk An   +7 more
doaj   +1 more source

Downregulation of Tumour Necrosis Factor α Gene Expression in Peripheral Blood Mononuclear Cells Cultured in the Presence of Tofacitinib Prior to Therapy Is Associated with Clinical Remission in Patients with Rheumatoid Arthritis

Current Issues in Molecular Biology, 2022
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by pain, synovial hyperplasia, mononuclear cell infiltration, bone erosion and joint destruction.
Elena V. Tchetina, Galina A. Markova, Azamat M. Satybaldyev, Aleksandr M. Lila   +3 more
doaj   +1 more source

Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis

STAR Protocols, 2022
Summary: By their capacity to induce peripheral T cell tolerance, dendritic cells (DCs) present a promising target cell and therapeutic strategy for treatment of several autoimmune diseases including multiple sclerosis (MS).
Andrea Vogel, Martina Kerndl, Gernot Schabbauer, Omar Sharif   +3 more
doaj   +1 more source

Influence of Preoperative Physical Function on Gait 1 Month After Total Knee Arthroplasty

Annals of Geriatric Medicine and Research, 2017
Background : This study aimed to identify the preoperative physical performance factors that predict gait speed and endurance 1 month after total knee arthroplasty (TKA).
So Young Lee, Bo Ryun Kim, Sang Rim Kim, Eun Young Han, Kwang Woo Nam, Yong-Geun Park   +5 more
doaj   +1 more source

Rheumatoid arthritis [PDF]

The Lancet, 2016
Rheumatoid arthritis is a chronic inflammatory joint disease, which can cause cartilage and bone damage as well as disability. Early diagnosis is key to optimal therapeutic success, particularly in patients with well-characterised risk factors for poor outcomes such as high disease activity, presence of autoantibodies, and early joint damage. Treatment
Smolen, Josef S., Aletaha, Daniel, McInnes, Iain B.   +2 more
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The risk of malignancy and its incidence in early rheumatoid arthritis patients treated with biologic DMARDs

Arthritis Research & Therapy, 2017
Background Treatment with disease-modifying anti-rheumatic drugs (DMARDs) has raised concerns about the risk of malignancies in rheumatoid arthritis (RA) patients.
Soo-Kyung Cho, Jiyoung Lee, Minkyung Han, Sang-Cheol Bae, Yoon-Kyoung Sung   +4 more
doaj   +1 more source

Author Correction: Associations between hand function and electrophysiological measurements in hand osteoarthritis patients of different ages with or without carpal tunnel syndrome

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Young Hoon Kim, Eun Young Han, Jinseok Kim, Kyu‑Bum Seo, Young Tae Jeon, Sang Hee Im   +5 more
doaj   +1 more source

Putative Association between Low Baseline Gene Expression in the Peripheral Blood and Clinical Remission in Rheumatoid Arthritis Patients Treated with Tofacitinib

Life, 2021
We investigated the importance of the baseline expression of genes involved in energy generation, as prognostic biomarkers of the treatment response to tofacitinib in patients with rheumatoid arthritis (RA). Peripheral blood samples were obtained from 28
Elena V. Tchetina, Azamat M. Satybaldyev, Galina A. Markova, Elena Yu. Samarkina, Aleksandr M. Lila   +4 more
doaj   +1 more source