Results 21 to 30 of about 589,621 (302)

Atherosclerosis in Rheumatoid Arthritis [PDF]

Mediators of Inflammation, 2012
There is a growing body of evidence supporting an increased risk of cardiovascular (CV) mortality in patients with rheumatoid arthritis (RA). This is the result of complex mechanisms leading to accelerated atherosclerosis [1]. In this regard, besides classic CV risk factors [2], chronic inflammation [3] and a genetic component [3, 4] have been proposed
Gonzalez-Gay, Miguel A, Szekanecz, Zoltan, Popa, Calin D, Dessein, Patrick   +3 more
openaire   +3 more sources

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin [PDF]

, 2005
Pathological processes involved in the initiation of rheumatoid synovitis remain unclear. We undertook the present study to identify immune and stromal processes that are present soon after the clinical onset of rheumatoid arthritis ( RA) by assessing a ...
A Bucht, AN Akbar, AN Akbar, Arne N Akbar, B Relic, BP Leung, C Jakubzick, Caroline Gordon, CD Buckley, CD Buckley, Chi-Yeung Lee, Christopher D Buckley, CM Weyand, D Pilling, DV Jovanovic, E Berglin, Emma J Ross, F Fossiez, F Santiago-Schwarz, FC Arnett, FM Brennan, FP Heinzel, Francesco Falciani, G Husby, G Parsonage, GS Firestein, GS Firestein, GS Firestein, H Visser, HR Schumacher, IB McInnes, J Kaufman, Janet M Lord, JM Bathon, K Raza, Karim Raza, L Breiman, LA Joosten, LJ Zhou, M Boers, M Salmon, M Salmon, M Sebbag, MC Blades, MG Chiaramonte, Mike Salmon, MJ Jacobs, MM Nielen, N Matthews, NJ Zvaifler, P Kurki, P Miossec, PG Conaghan, PK Gregersen, PP Tak, R Bucala, R Gerli, RL Modlin, S John Curnow, SJ Curnow, SK Seo, T Mottonen, T Pap, TF Cox, Y Benjamini, Y Morita   +65 more
core   +2 more sources

Expression of activation-induced cytidine deaminase splicing variants in patients with ankylosing spondylitis

Autoimmunity, 2017
To investigate the expression patterns of activation-induced cytidine deaminase (AID) variants in peripheral blood mononuclear cells (PBMCs) of patients with ankylosing spondylitis (AS) and examine their clinical implications, we isolated PBMCs from ...
Ji-Young Kim, Hee-Kyung Yoon, Seung Taek Song, Seok-Rae Park, Seung-Cheol Shim   +4 more
doaj   +1 more source

The risk of malignancy and its incidence in early rheumatoid arthritis patients treated with biologic DMARDs

Arthritis Research & Therapy, 2017
Background Treatment with disease-modifying anti-rheumatic drugs (DMARDs) has raised concerns about the risk of malignancies in rheumatoid arthritis (RA) patients.
Soo-Kyung Cho, Jiyoung Lee, Minkyung Han, Sang-Cheol Bae, Yoon-Kyoung Sung   +4 more
doaj   +1 more source

Association between serum bone biomarker levels and therapeutic response to abatacept in patients with rheumatoid arthritis (RA): a multicenter, prospective, and observational RA ultrasound cohort study in Japan

BMC Musculoskeletal Disorders, 2021
Background To evaluate the effect of treatment on serum bone biomarkers and explore whether serum bone biomarkers are associated with therapeutic response in rheumatoid arthritis (RA) patients treated with abatacept.
Shin-ya Kawashiri, Yushiro Endo, Ayako Nishino, Momoko Okamoto, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Tomohiro Koga, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Toshiyuki Aramaki, Yukitaka Ueki, Tamami Yoshitama, Nobutaka Eiraku, Naoki Matsuoka, Akitomo Okada, Keita Fujikawa, Hiroaki Hamada, Shuji Nagano, Yoshifumi Tada, Atsushi Kawakami   +24 more
doaj   +1 more source

Change in bone mineral density in post menopausal women with rheumatoid arthritis [PDF]

, 2013
Introduction: Low bone mass is a serious complication of post menopausal women with rheumatoid arthritis. We determined the Change in Bone Mineral Density in postmenopausal women with rheumatoid arthritis.
Aghaei, M., Aili, A., Jamshir, M., Khani, S.H., Mohebi, E.G., Pour, N.B., Sedighi, S., Shirashiani, M., Shojaa, M., Zayeni, H.   +9 more
core   +1 more source

RHEUMATOID ARTHRITIS [PDF]

BMJ, 1913
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openaire   +3 more sources

IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway

Infectious Agents and Cancer, 2023
Metastasis has emerged as a major impediment to achieve successful therapeutic outcomes in hepatocellular carcinoma (HCC). Nonetheless, the intricate molecular mechanisms governing the progression of HCC remain elusive.
Xiu Chen, Yu Zhang, Pingping Zhang, Mengzhu Wei, Tian Tian, Yanling Guan, Chenchen Han, Wei Wei, Yang Ma   +8 more
doaj   +1 more source

Ann Rheum Dis [PDF]

, 2011
Objective This study was conducted with sera from patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and arthritis and lupus-like disease animal models to identify innate immune system-dependent and -independent ...
Burmester, G., Häupl, T., Konthur, Z., Marklein, B., Shlomchik, M., Skriner, K.   +5 more
core   +2 more sources

β2 Integrins As Regulators of Dendritic Cell, Monocyte, and Macrophage Function

Frontiers in Immunology, 2017
Emerging evidence suggests that the β2 integrin family of adhesion molecules have an important role in suppressing immune activation and inflammation.
Leonie Schittenhelm, Leonie Schittenhelm, Leonie Schittenhelm, Catharien M. Hilkens, Catharien M. Hilkens, Vicky L. Morrison, Vicky L. Morrison   +6 more
doaj   +1 more source