Results 21 to 30 of about 590,156 (281)

Downregulation of Tumour Necrosis Factor α Gene Expression in Peripheral Blood Mononuclear Cells Cultured in the Presence of Tofacitinib Prior to Therapy Is Associated with Clinical Remission in Patients with Rheumatoid Arthritis

Current Issues in Molecular Biology, 2022
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by pain, synovial hyperplasia, mononuclear cell infiltration, bone erosion and joint destruction.
Elena V. Tchetina, Galina A. Markova, Azamat M. Satybaldyev, Aleksandr M. Lila   +3 more
doaj   +1 more source

Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis

STAR Protocols, 2022
Summary: By their capacity to induce peripheral T cell tolerance, dendritic cells (DCs) present a promising target cell and therapeutic strategy for treatment of several autoimmune diseases including multiple sclerosis (MS).
Andrea Vogel, Martina Kerndl, Gernot Schabbauer, Omar Sharif   +3 more
doaj   +1 more source

Influence of Preoperative Physical Function on Gait 1 Month After Total Knee Arthroplasty

Annals of Geriatric Medicine and Research, 2017
Background : This study aimed to identify the preoperative physical performance factors that predict gait speed and endurance 1 month after total knee arthroplasty (TKA).
So Young Lee, Bo Ryun Kim, Sang Rim Kim, Eun Young Han, Kwang Woo Nam, Yong-Geun Park   +5 more
doaj   +1 more source

Association between serum bone biomarker levels and therapeutic response to abatacept in patients with rheumatoid arthritis (RA): a multicenter, prospective, and observational RA ultrasound cohort study in Japan

BMC Musculoskeletal Disorders, 2021
Background To evaluate the effect of treatment on serum bone biomarkers and explore whether serum bone biomarkers are associated with therapeutic response in rheumatoid arthritis (RA) patients treated with abatacept.
Shin-ya Kawashiri, Yushiro Endo, Ayako Nishino, Momoko Okamoto, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Tomohiro Koga, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Toshiyuki Aramaki, Yukitaka Ueki, Tamami Yoshitama, Nobutaka Eiraku, Naoki Matsuoka, Akitomo Okada, Keita Fujikawa, Hiroaki Hamada, Shuji Nagano, Yoshifumi Tada, Atsushi Kawakami   +24 more
doaj   +1 more source

Putative Association between Low Baseline Gene Expression in the Peripheral Blood and Clinical Remission in Rheumatoid Arthritis Patients Treated with Tofacitinib

Life, 2021
We investigated the importance of the baseline expression of genes involved in energy generation, as prognostic biomarkers of the treatment response to tofacitinib in patients with rheumatoid arthritis (RA). Peripheral blood samples were obtained from 28
Elena V. Tchetina, Azamat M. Satybaldyev, Galina A. Markova, Elena Yu. Samarkina, Aleksandr M. Lila   +4 more
doaj   +1 more source

Author Correction: Associations between hand function and electrophysiological measurements in hand osteoarthritis patients of different ages with or without carpal tunnel syndrome

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Young Hoon Kim, Eun Young Han, Jinseok Kim, Kyu‑Bum Seo, Young Tae Jeon, Sang Hee Im   +5 more
doaj   +1 more source

RHEUMATOID ARTHRITIS [PDF]

BMJ, 1913
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openaire   +3 more sources

Expression of activation-induced cytidine deaminase splicing variants in patients with ankylosing spondylitis

Autoimmunity, 2017
To investigate the expression patterns of activation-induced cytidine deaminase (AID) variants in peripheral blood mononuclear cells (PBMCs) of patients with ankylosing spondylitis (AS) and examine their clinical implications, we isolated PBMCs from ...
Ji-Young Kim, Hee-Kyung Yoon, Seung Taek Song, Seok-Rae Park, Seung-Cheol Shim   +4 more
doaj   +1 more source

The risk of malignancy and its incidence in early rheumatoid arthritis patients treated with biologic DMARDs

Arthritis Research & Therapy, 2017
Background Treatment with disease-modifying anti-rheumatic drugs (DMARDs) has raised concerns about the risk of malignancies in rheumatoid arthritis (RA) patients.
Soo-Kyung Cho, Jiyoung Lee, Minkyung Han, Sang-Cheol Bae, Yoon-Kyoung Sung   +4 more
doaj   +1 more source

IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway

Infectious Agents and Cancer, 2023
Metastasis has emerged as a major impediment to achieve successful therapeutic outcomes in hepatocellular carcinoma (HCC). Nonetheless, the intricate molecular mechanisms governing the progression of HCC remain elusive.
Xiu Chen, Yu Zhang, Pingping Zhang, Mengzhu Wei, Tian Tian, Yanling Guan, Chenchen Han, Wei Wei, Yang Ma   +8 more
doaj   +1 more source