Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways
Class 1 Phosphoinositide-3-Kinases (PI3Ks) have been widely studied and mediate essential roles in cellular proliferation, chemotaxis, insulin sensitivity, and immunity.
Omar Sharif+7 more
doaj +1 more source
Clinical studies on electromyographic changes in rheumatoid arthritis Part III. Effect of radioactive hot spring baths [PDF]
The author observed the changes in electromyographic patterns of 14 patients with rheumatoid arthritis (13 cases of classical rheumatoid arthritis and one case of definite rheumatoid arthritis) bathed 2 or 3 times daily in hot spring water at Misasa Spa,
Ikegami, Tadaoki
core +1 more source
Prevalence of Sexual Disorders in Patients With Rheumatoid Arthritis and Associated Factors
Introduction: Rheumatoid arthritis (RA) is a chronic and progressive pathology, present in between 0.5% and 1% of adults. Sexual disorders (SDs) occur in between 31% and 70% of all patients with RA.
Pedro Santos-Moreno, MD, MSc+3 more
doaj
ObjectiveDendritic cells (DCs) are key orchestrators of immune function. To date, rheumatoid arthritis (RA) researchers have predominantly focused on a potential pathogenic role for CD1c+ DCs.
Faye A. H. Cooles+15 more
doaj +1 more source
Rheumatoid meningitis sine arthritis. [PDF]
Rheumatoid meningitis is a rare and very serious extra-articular manifestation of rheumatoid arthritis. We present a case of a 7()year-old female with no history of arthritis who developed stroke-like symptoms, seizures, psychosis and compulsive behavior.
Berk, Matthew+3 more
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Shared epitope alleles remain a risk factor for anti-citrullinated proteins antibody (ACPA)--positive rheumatoid arthritis in three Asian ethnic groups. [PDF]
BACKGROUND: To investigate the associations between HLA-DRB1 shared epitope (SE) alleles and rheumatoid arthritis in subsets of rheumatoid arthritis defined by autoantibodies in three Asian populations from Malaysia.
Too Chun-Lai+10 more
doaj +1 more source
Systematic review of the psychometric properties of patient-reported outcome measures for foot and ankle in rheumatoid arthritis [PDF]
Background Foot problems and pain are common in patients with rheumatoid arthritis. Patient-reported outcome measures provide a standardized method of capturing patients’ perspectives of their functional status and wellbeing.
Cervera Garvi, Pablo+4 more
core
The outcome and cost-effectiveness of nurse-led care in the community for people with rheumatoid arthritis:a non-randomised pragmatic study [PDF]
To determine the outcome and cost-effectiveness of nurse-led care in the community for people with rheumatoid arthritis (RA)
Abdelhamid+35 more
core +1 more source