Results 41 to 50 of about 1,208,132 (384)

Effect of a small molecule inhibitor of nuclear factor-κB nuclear translocation in a murine model of arthritis and cultured human synovial cells [PDF]

, 2005
A small cell-permeable compound, dehydroxymethylepoxyquinomicin (DHMEQ), does not inhibit phosphorylation and degradation of IκB (inhibitor of nuclear factor-κB [NF-κB]) but selectively inhibits nuclear translocation of activated NF-κB.
Kubota, Tetsuo, Miyasaka, Nobuyuki, Nanki, Toshihiro, Umezawa, Kazuo, Wakamatsu, Kyoko   +4 more
core   +2 more sources

A Sub-pixel Accurate Quantification of Joint Space Narrowing Progression in Rheumatoid Arthritis [PDF]

, 2022
Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects peripheral synovial joints, like fingers, wrist and feet. Radiology plays a critical role in the diagnosis and monitoring of RA. Limited by the current spatial resolution of radiographic imaging, joint space narrowing (JSN) progression of RA with the same reason above can ...
arxiv   +1 more source

Viscoelastic properties of human and bovine articular cartilage : a comparison of frequency-dependent trends [PDF]

, 2016
Acknowledgments The authors would like to thank Spencer C. Barnes and Hamid Sadeghi for assistance during experimentation. We would also like to thank patients donating tissue and the surgeons collecting these.
Aspden, Richard M., Aspden, Richard M., Cederlund, Anna A., Espino, Daniel M., Lawless, Bernard M., Temple, Duncan K.   +5 more
core   +3 more sources

Integrating clinician support with intervention design as part of a programme testing stratified care for musculoskeletal pain in general practice

BMC Family Practice, 2021
Background Stratified care involves subgrouping patients based on key characteristics, e.g. prognostic risk, and matching these subgroups to early treatment options.
Joanne Protheroe, Benjamin Saunders, Jonathan C. Hill, Adrian Chudyk, Nadine E. Foster, Bernadette Bartlam, Simon Wathall, Vincent Cooper   +7 more
doaj   +1 more source

Employing Feature Selection Algorithms to Determine the Immune State of a Mouse Model of Rheumatoid Arthritis [PDF]

arXiv, 2022
The immune response is a dynamic process by which the body determines whether an antigen is self or nonself. The state of this dynamic process is defined by the relative balance and population of inflammatory and regulatory actors which comprise this decision making process. The goal of immunotherapy as applied to, e.g. Rheumatoid Arthritis (RA), then,
arxiv  

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70 [PDF]

, 2018
Various subsets of invariant natural killer T (iNKT) cells with different cytokine productions develop in the mouse thymus, but the factors driving their differentiation remain unclear.
A Hutloff, AK Stanic, B San Luis, BB Au-Yeung, BB Au-Yeung, CQ Chu, D Davidson, DG Pellicci, DG Pellicci, DG Wei, DI Godfrey, EJ Wherry, F Scheuplein, F Scheuplein, FW McNab, G Anderson, G Fu, G Kollias, G Seumois, H Georgiev, H Watarai, HS Azzam, I Engel, I Engel, J Henao-Mejia, J Novak, J Zikherman, JL Matsuda, JL Matsuda, JM Mason, K Benlagha, K Hirota, K Oleinika, K Yamamoto, L Brossay, L Linsen, LH Mason, LM D'Cruz, M Cruz Tleugabulova, M Gaya, M Guma, M Hashimoto, M Kronenberg, M Zhu, MA Weinreich, MB Drennan, MC Leite-De-Moraes, MC Leite-De-Moraes, MI Zimmer, MP Seiler, N Bottini, N Sakaguchi, NA Nagarajan, R Genolet, RJ Martinez, S Akbulut, S Jung, S Picelli, S Sidobre, SE Levin, TN Newman, V Cerundolo, V Sivakumar, WY Lee, X Li, YJ Lee, YL Chiu   +66 more
core   +4 more sources

Infectious arthritis in patients with rheumatoid arthritis. [PDF]

Annals of the Rheumatic Diseases, 1992
Eleven cases of infectious arthritis occurring in patients with rheumatoid arthritis are reported. Staphylococcus aureus was the causative organism in eight patients. Streptococcus anginosus and Streptococcus agalactiae in one patient each, and Mycobacterium tuberculosis in two patients.
Mateo Soria, Lourdes, Nolla Solé, Joan Miquel, Rozadilla Sacanell, Antoni, Valverde García, José, Roig Escofet, D. (Daniel)   +4 more
openaire   +4 more sources

A Deep Registration Method for Accurate Quantification of Joint Space Narrowing Progression in Rheumatoid Arthritis [PDF]

, 2023
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that results in progressive articular destruction and severe disability. Joint space narrowing (JSN) progression has been regarded as an important indicator for RA progression and has received sustained attention. In the diagnosis and monitoring of RA, radiology plays a crucial role
arxiv   +1 more source

Examining the Association Between Traditional and Mainstream Medicine and the Prevalence of Arthritis in the Urban Indigenous Population Living in Toronto [PDF]

, 2020
Background: In the Indigenous community, the prevalence of arthritis is 1.3 to 1.6 times higher than their non-Indigenous counterparts. Moreover, minimal population health information on urban Indigenous peoples is available.
Chen, Julio Cristian
core  

Osteoclasts and Arthritis [PDF]

Journal of Bone and Mineral Research, 2009
INFLAMMATORY ARTHRITIS TYPICALLY presents as joint pain, swelling, and stiffness, which may be of short duration. For example, parvovirus B 19 infection, attended by painful polyarticular swelling, generally resolves spontaneously within 2 wk without joint destruction.
Georg Schett, Steven L. Teitelbaum
openaire   +3 more sources