Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70 [PDF]
, 2018 Various subsets of invariant natural killer T (iNKT) cells with different cytokine productions develop in the mouse thymus, but the factors driving their differentiation remain unclear.
A Hutloff +66 more
core +4 more sources
Early Failure of Total Ankle Arthroplasty in a Patient with Ipsilateral Varus Knee Deformity
Case Reports in Orthopedics, 2021 Multiple risk factors such as age, body mass index (BMI), preoperative diagnosis, smoking, diabetes mellitus, malalignment of an implant, and presence of ipsilateral hindfoot fusion have been shown to contribute to failure of total ankle arthroplasty ...
Taehyeon Kim +5 more
doaj +1 more source
Examining the Association Between Traditional and Mainstream Medicine and the Prevalence of Arthritis in the Urban Indigenous Population Living in Toronto [PDF]
, 2020 Background: In the Indigenous community, the prevalence of arthritis is 1.3 to 1.6 times higher than their non-Indigenous counterparts. Moreover, minimal population health information on urban Indigenous peoples is available.
Chen, Julio Cristian
core
Frontiers in Bioengineering and Biotechnology, 2022 Objective: With the development of extracellular vesicles (EVs) based on stem cells research all over the world, our present study was aiming to discover the global trends in this field.Methods: All publications related to EVs based on stem cells from ...
Jianjing Lin +9 more
doaj +1 more source
Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance [PDF]
, 2012 INTRODUCTION Endosomal toll-like receptors (TLRs) have recently emerged as potential contributors to the inflammation observed in human and rodent models of rheumatoid arthritis (RA).
Alzabin, Saba +5 more
core +1 more source
Stem Cells Translational Medicine, 2019 Patients with late‐stage Kellgren‐Lawrence knee osteoarthritis received a single intra‐articular injection of 1, 10, or 50 million bone marrow mesenchymal stromal cells (BM‐MSCs) in a phase I/IIa trial to assess safety and efficacy using a broad toolset ...
Jaskarndip Chahal +18 more
doaj +1 more source
Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies
Bone Research, 2018 Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily affects the lining of the synovial joints and is associated with progressive disability, premature death, and socioeconomic burdens.
Qiang Guo +5 more
semanticscholar +1 more source
Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis
Nature Communications, 2020 Gut microbial dysbiosis is associated with the development of autoimmune disease, but the mechanisms by which microbial dysbiosis affects the transition from asymptomatic autoimmunity to inflammatory disease are incompletely characterized.
N. Tajik +28 more
semanticscholar +1 more source
BMJ, 1963 Excerpt The significance of the association of psoriasis with arthritis has been controversial since Alibert (1) and Bourdillon (2) described patients in whom the 2 diseases coexisted.
H, BAKER, D N, GOLDING, M, THOMPSON
openaire +3 more sources
Protocol for the Foot in Juvenile Idiopathic Arthritis trial (FiJIA): a randomised controlled trial of an integrated foot care programme for foot problems in JIA [PDF]
, 2009 <b>Background</b>: Foot and ankle problems are a common but relatively neglected manifestation of juvenile idiopathic arthritis. Studies of medical and non-medical interventions have shown that clinical outcome measures can be improved ...
A Manca +60 more
core +4 more sources