Results 51 to 60 of about 1,208,132 (384)
BMC Musculoskeletal Disorders, 2018 Background Angioleiomyoma is a very rare benign solitary soft tissue neoplasm originating from smooth muscle layer of blood vessels. The tumor is usually located in the subcutis or the superficial fasciae, but less often in the deep fasciae, especially ...
Chenxi Cao +5 more
doaj +1 more source
Quantitative predictive modelling approaches to understanding rheumatoid arthritis: A brief review [PDF]
, 2019 Rheumatoid arthritis is a chronic autoimmune disease that is a major public health challenge. The disease is characterised by inflammation of synovial joints and cartilage erosion, which leads to chronic pain, poor life quality and, in some cases, premature mortality.
arxiv +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
BMC RheumatologyBackground Thrombotic events, such as venous thromboembolism (VTE) are a major health complication linked to rheumatoid arthritis (RA). We performed a meta-analysis to evaluate the risk of VTE, including deep vein thrombosis (DVT) and pulmonary embolism (
Zahra A Fazal +5 more
doaj +1 more source
The performance of different classification criteria sets for spondyloarthritis in the worldwide ASAS-COMOSPA study [PDF]
, 2017 Background: In this study, we sought to compare the performance of spondyloarthritis (SpA) classification criteria sets in an international SpA cohort with patients included from five continents around the world.
Bakker, Pauline +7 more
core +2 more sources
FEBS Open Bio, EarlyView.GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda +15 more
wiley +1 more source
BMC Rheumatology, 2022 Background Gout may be associated with an increased incidence of mental health disorders, however, published findings have been limited and inconsistent. Therefore, our objective was to conduct a population-based cohort study to evaluate the incidence of
Alyssa Howren +6 more
doaj +1 more source
Mitochondria as Key Players in the Pathogenesis and Treatment of Rheumatoid Arthritis
Frontiers in Immunology, 2021 Mitochondria are major energy-producing organelles that have central roles in cellular metabolism. They also act as important signalling hubs, and their dynamic regulation in response to stress signals helps to dictate the stress response of the cell ...
Sally A. Clayton +7 more
doaj +1 more source
Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction in Staphylococcus aureus-induced arthritis [PDF]
, 2018 Background: Staphylococcus aureus-induced arthritis causes rapid joint destruction, often leading to disabling joint damage despite antibiotics. We have previously shown that IL-15 inhibition without antibiotics is beneficial in S.
Bergmann, Berglind +7 more
core +1 more source
Vitamin D and early rheumatoid arthritis
BMC Rheumatology, 2020 Background Previous studies have linked rheumatoid arthritis (RA) risk and disease activity with vitamin D-deficiency (low serum 25-hydroxyvitamin D (25OHD)), but a causal role for vitamin D in RA is still unclear, with conflicting results from many ...
Stephanie R. Harrison +6 more
doaj +1 more source