Results 101 to 110 of about 9,355 (209)

Regulating obesity-induced osteoarthritis by targeting p53-FOXO3, osteoclast ferroptosis, and mesenchymal stem cell adipogenesis

Nature Communications
Obesity-related osteoarthritis (OA) and the molecular mechanisms governing multiple joint structural changes that occur with obesity are not well understood. This study investigated the progression of obesity in mice and validated the results using human
Chen Zhao, Keyu Kong, Pengcheng Liu, Xuzhuo Chen, Kewei Rong, Pu Zhang, Lei Wang, Xiaoqing Wang   +7 more
doaj   +1 more source

Medial meniscus posterior root tears with advanced osteoarthritis or subchondral insufficiency fracture are good indications for unicompartmental knee arthroplasty at a minimum 2-year follow-up

Archives of Orthopaedic and Trauma Surgery
Abstract Introduction The outcomes of unicompartmental knee arthroplasty (UKA) in the presence and absence of medial meniscus posterior root tears (MMPRTs) have not been compared. This study compared the characteristics and clinical outcomes of patients undergoing UKA with and without MMPRTs.
Koki Kawada, Yusuke Yokoyama, Yuki Okazaki, Masanori Tamura, Toshifumi Ozaki, Takayuki Furumatsu   +5 more
openaire   +3 more sources

Rapid Destruction of the Humeral Head Caused by Subchondral Insufficiency Fracture: A Report of Two Cases

Case Reports in Orthopedics, 2015
Rapidly destructive arthritis (RDA) of the shoulder is a rare disease. Here, we report two cases, with different destruction patterns, which were most probably due to subchondral insufficiency fractures (SIFs).
Kenichi Goshima, Katsuhiko Kitaoka, Junsuke Nakase, Hiroyuki Tsuchiya   +3 more
doaj   +1 more source

Avascular Necrosis and Subchondral Collapse of the Femoral Head After Intra-Articular Corticosteroid Injection: A Case Report

SurgiColl
A 51-year-old female with no history of chronic alcohol or steroid use presented with right hip pain. X-ray and magnetic resonance imaging (MRI) showed osteoarthritic changes without evidence of avascular necrosis (AVN) or subchondral collapse of the ...
Shelby Cowan, Kassem Ghayyad, Patrick King   +2 more
doaj   +1 more source

Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips

, 2017
Osteoarthritis (OA) is a progressively degenerative joint disease influenced by structural and metabolic factors. There is growing evidence that subchondral bone is involved in both symptomatic and structural progression in OA.
Zarei, A, Hulley, Philippa, Philippa A. Hulley, Hulley, PA, M. Kassim Javaid, Sabokbar, A, Afsie Sabokbar, Sabokbar, Afsaneh, Javaid, MK, Javaid, M. Kassim, Allahdad Zarei   +10 more
core   +1 more source

A comparison of subchondral bone mineralization between the glenoid cavity and the humeral head on 57 cadaverous shoulder joints

, 2013
PURPOSE: Mineralization distribution of the subchondral bone plate can be used as a marker for long-term stress distribution in diarthrodial joints. Severe injuries or pathological changes of the glenohumeral joint often end in osteoarthritis, where ...
Muller-Gerbl, M., Hugli, R., Zumstein, V., Kraljevic, M.   +3 more
core   +1 more source

Quantification of histological subtypes within osteoarthritic subchondral bone cysts [PDF]

, 2018
Osteoarthritis is a degenerative bone disease that affects over 27 million Americans (Neogi, 2013). It is characterized by the loss of functional cartilage that normally bears mechanical stresses, which is then transferred onto bone and leads to ...
Babbin, Joshua
core  

Increased vascularization of the subchondral region in human osteoarthritic femoral head in the elderly

This study aimed to quantitatively analyze subchondral vascularization during the progression of osteoarthritis (OA) in the elderly, particularly regarding the timing of initial blood vessel emergence and when their density peaks.
Schilling, Arndt F., Neunaber, Claudia, Stauß, Ricarda, Mühlfeld, Christian, Sehmisch, Stephan, He, Yuqi, Taheri, Shahed, Graulich, Tilman, Liodakis, Emmanouil, Bundkirchen, Katrin   +9 more
core   +1 more source

GLENOID STRUCTURAL ANALYSIS: RELEVANCE TO ARTHROPLASTY [PDF]

, 2004
Total shoulder arthroplasty restores function in shoulders with end stage glenohumeral arthritis. The most common complication of arthroplasty is prosthesis loosening and glenoid prosthesis loosening occurs more frequently than humeral because of ...
Sharma, Gulshan Baldev
core  

Bone Marrow Aspirate Concentrate (BMAC) for Knee Osteoarthritis: A Narrative Review of Clinical Efficacy and Future Directions

Medicina
Bone marrow aspirate concentrate (BMAC) is an autologous regenerative therapy enriched with mesenchymal stem cells (MSCs) and bioactive growth factors, offering potential disease-modifying effects in knee osteoarthritis (OA).
Dojoon Park, Hae-Seok Koh, Youn-Ho Choi, Ilkyu Park   +3 more
doaj   +1 more source