Results 71 to 80 of about 48,742 (271)

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Reconstructing the phylogeny of 21 completely sequenced arthropod species based on their motor proteins

BMC Genomics, 2009
Background Motor proteins have extensively been studied in the past and consist of large superfamilies. They are involved in diverse processes like cell division, cellular transport, neuronal transport processes, or muscle contraction, to name a few ...
Kollmar Martin, Becker Sebastian, Odronitz Florian   +2 more
doaj   +1 more source

Diverse Begomoviruses Evolutionarily Hijack Plant Terpenoid-Based Defense to Promote Whitefly Performance

Cells, 2022
Arthropod-borne pathogens and parasites are major threats to human health and global agriculture. They may directly or indirectly manipulate behaviors of arthropod vector for rapid transmission between hosts.
Ning Wang, Pingzhi Zhao, Duan Wang, Muhammad Mubin, Rongxiang Fang, Jian Ye   +5 more
doaj   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

Rickettsial pathogen augments tick vesicular-associated membrane proteins for infection and survival in the vector host

mBio
Anaplasma phagocytophilum is an obligate intracellular rickettsial pathogen that infects humans and animals. The black-legged tick Ixodes scapularis acts as a vector and transmits this bacterium to the vertebrate host.
Prachi Namjoshi, Jaydeep Kolape, Avni Patel, Hameeda Sultana, Girish Neelakanta   +4 more
doaj   +1 more source

Transgenic Bt Cotton Does Not Disrupt the Top-Down Forces Regulating the Cotton Aphid in Central China. [PDF]

PLoS ONE, 2016
Top-down force is referred to arthropod pest management delivered by the organisms from higher trophic levels. In the context of prevalent adoption of transgenic Bt crops that produce insecticidal Cry proteins derived from Bacillus thuringiensis (Bt), it
Yong-Sheng Yao, Peng Han, Chang-Ying Niu, Yong-Cheng Dong, Xi-Wu Gao, Jin-Jie Cui, Nicolas Desneux   +6 more
doaj   +1 more source

New insights into control of arbovirus replication and spread by insect RNA interference pathways [PDF]

, 2012
Arthropod-borne (arbo) viruses are transmitted by vectors, such as mosquitoes, to susceptible vertebrates. Recent research has shown that arbovirus replication and spread in mosquitoes is not passively tolerated but induces host responses to control ...
Andersson, Angelini, Angelini, Arensburger, Arensburger, Attarzadeh-Yazdi, Berry, Blevins, Brackney, Chung, Cirimotich, Cohen, Czech, Ding, Dubrulle, Fagegaltier, Flynt, Franz, Ghildiyal, Henke, Holt, Hussain, Hussain, Iwasaki, Kaminker, Kawamura, Keene, Kwon, Lagos-Quintana, Li, Lim, Lucchetta, Mendes, Morazzani, Mueller, Myles, Nene, Qi, Rezza, Ruby, Saleh, Sanchez-Vargas, Schwarz, Selbach, Sijen, Siu, Skalsky, Tam, Thibault, Vodovar, Watanabe, Waterhouse, Wu, Yan, Zeiner, Zeng   +55 more
core   +3 more sources

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Towards a Universal Translator: Decoding the PTMs That Regulate Orthoflavivirus Infection

Viruses
Post-translational modifications (PTMs) serve as critical regulators of protein function across biological systems, including during viral infection. For orthoflaviviruses, including human pathogens like dengue, Zika, and West Nile viruses, PTMs on viral
Hannah M. Schmidt, Stacy M. Horner
doaj   +1 more source

Dengue virus downregulates TNFR1- and TLR3-stimulated NF-κB activation by targeting RIPK1

Frontiers in Cellular and Infection Microbiology, 2022
Dengue virus (DENV) infection is the most prevalent arthropod-borne virus disease and is endemic in more than 100 countries. Several DENV proteins have been shown to target crucial human host proteins to evade innate immune responses and establish a ...
Darshika J. Udawatte, Diane M. Lang, Jeffrey R. Currier, Carey L. Medin, Alan L. Rothman   +4 more
doaj   +1 more source