β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Roles of Gag and NCp7 in Facilitating \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathbf{tRNA}_{3}^{\mathbf{Lys}}\) \end{document} Annealing to Viral RNA in Human Immunodeficiency Virus Type 1 [PDF]
, 2009 Fei Guo +3 more
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Overview of Bjelland Vineyards Article [PDF]
, 1976 This article relates the origin story of Bjelland Vineyards and its available wines, including an invitation from Paul and Mary Bjelland to visit the winery and enjoy a picnic on their property.
The News-Review
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Workplace Violence Intervention Research Workshop, April 5–7, 2000, Washington, DC11The full text of this article is temporarily available until February 2002 via AJPM Online at www:elsevier.com/locate/ajpmonline. [PDF]
, 2001 James A. Merchant, John Lundell
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Electronic spin working mechanically (Review Article) [PDF]
, 2014 R. I. Shekhter +7 more
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Country Policy Framework for Cooperative Approaches Under Article 6.2
, 2021 World Bank
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Micropropagation and In Vitro Secondary Metabolites Production of Ocimum Species. Review Article [PDF]
, 2017 M. Kasem
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