Results 11 to 20 of about 129,812 (243)

Association of African states with the EEC [PDF]

open access: yes, 2008
The Yaoundé Agreement, which was signed on July 20, 1963, by the EEC and 18 African states as well as Madagascar, and became effective on June 1, 1964, is due to expire on May 30, 1969.
Hendus, H.
core   +1 more source

Article 30 EEC: Caution in the European Court [PDF]

open access: yesThe Modern Law Review, 1990
In July 1987, the Court of Appeal made use of Article 177 EEC to refer to the European Court issues relating to the interpretation of Article 30 EEC which had arisen in R v The Pharmaceutical Society of Great Britain, ex parte the Association of Pharmaceutical Importers (API).' In a previous issue of the Review, this commentator concluded his ...
openaire   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Government Equity Participation Under the EEC Rules on State Aids: Recent Developments [PDF]

open access: yes, 1987
This Article examines the main legal questions raised by the particulat form of State aid known as equity participation. While the focus is on the internal, or EEC, aspect of such aids, the Article also suggests a comparison to some of the most relevant ...
Pappalardo, Aurelio
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The European Community\u27s Environmental Policy: A Case-Study in Federalism [PDF]

open access: yes, 1988
This article will examine the European Community’s environmental policy and how spill-over effects in that area led to a transfer of powers from the Member-State to the Community level.
Haagsma, Auke
core   +1 more source

The Unresolved Tension Between Trademark Protection and Free Movement of Goods in the European Community [PDF]

open access: yes, 1992
Developments in computer-aided engineering and the rapid growth of computational power have made simulation-driven process and product development efficient and useful since it enables detailed evaluation of product designs and their manufacturing ...
Smith, Robert S.
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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