Results 41 to 50 of about 3,350,170 (238)

The studing of the Battle of Stalingrad and the restoration of Stalingrad at the Volgograd State University

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2013
The contribution of historians of Volgograd State University to studying of the history of the Battle of Stalingrad and restoration of Stalingrad is considered in the article: forming of the scientific schools, publication of monographs and collections ...
Redkina Olga Yuryevna
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Twenty articles in didactics of mathematics by Pranas Mašiotas

open access: yesLietuvos Matematikos Rinkinys, 2008
For many years, Pranas Mašiotas (1863–1940) was engaged as a teacher of mathematics, a director of gymnasium and a vice-minister of education. He compiled a number of mathematical manuals for Lithuanian primary and secondary schools.
Algirdas Ažubalis
doaj   +1 more source

Drawing the Scientific Collaboration Map of Intellectual Capital Field in the Web of Science [PDF]

open access: yesمجله علم‌سنجی کاسپین, 2021
Background and aim: Drawing the scientific collaboration maps is very important for analyzing and identifying scientific collaborations in different subject areas of science.
Ali Sharafi, Ali Shaghaghi
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

A Systematic Review of the Characteristics of Articles Published in the Politics Quarterly, Journal of University of Tehran [PDF]

open access: yesمجله علم‌سنجی کاسپین, 2021
Background and aim: One of the main indicators of the development of a science discipline is the scientific outputs and articles. The aim of this study was to investigate the characteristics of articles published in the Politics Quarterly, Journal of ...
Yahya Kamali   +1 more
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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