Results 121 to 130 of about 906,749 (336)

Experimental joint immobilization in guinea pigs. Effects on the knee joint [PDF]

open access: yes
In young and adult guinea pigs, the aftermath experimentally induced by the immobilization of the knee joint in hyperextended forced position was studied. Joint immobilization which varied from one to nine weeks was attained by plaster.
Machado, F. F.   +3 more
core   +1 more source

Dead Matter, Living Machines: Repurposing Crustaceans' Abdomen Exoskeleton for Bio‐Hybrid Robots

open access: yesAdvanced Science, EarlyView.
Crustacean exoskeletons, repurposed from food waste, are engineered into sustainable bending actuators combining biotic structure with synthetic control. The augmented exoskeletons achieve rapid and robust motion with lightweight body and can be used as part of robotic manipulators, grippers and swimmers.
Sareum Kim, Kieran Gilday, Josie Hughes
wiley   +1 more source

Increased Intestinal Permeability and Articular Involvement in Systemic Lupus Erythematosus Patients—A Mutually Exclusive Relationship?

open access: yesCurrent Issues in Molecular Biology
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder characterized by complex interactions between the innate and adaptive immune systems, being potentially associated with an enhanced intestinal permeability.
Cristian-Mihai Ilie   +6 more
doaj   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

open access: yesAdvanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng   +7 more
wiley   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

open access: yesAdvanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin   +10 more
wiley   +1 more source

3D‐Printed Ion‐Conductive Hydrogels with Tunable Mechanical–Electrical Properties for Multimodal Sign Language Recognition

open access: yesAdvanced Science, EarlyView.
This work successfully fabricated ion‐conductive hydrogels with low hysteresis and high conductivity using 3D printing technology. By adjusting the component ratios, the properties of the hydrogels can be tuned to meet diverse sensing requirements. Finally, a multimodal sensing sign language recognition system was constructed based on this hydrogel ...
Quan Hu   +9 more
wiley   +1 more source

Vascular Stromal Fraction Augmented With Autologous Cartilage Particulate and Hyaluronic Acid Mesh for the Treatment of Focal Cartilage Lesions: Description of a Surgical Technique

open access: yesArthroscopy Techniques
This study presents a surgical approach combining adipose-derived stromal vascular fraction, autologous cartilage particulate, and a hyaluronic acid mesh to treat focal cartilage lesions.
Gustavo Álvarez, M.D.   +6 more
doaj   +1 more source

Biologic Characteristics of Shoulder Articular Cartilage in Comparison to Knee and Ankle Articular Cartilage From Individual Donors [PDF]

open access: bronze, 2019
Susanna Chubinskaya   +5 more
openalex   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

open access: yesAdvanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin   +13 more
wiley   +1 more source

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