Results 111 to 120 of about 97,392 (285)
Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans
The Anatomical Record, EarlyView.Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban +3 more
wiley +1 more source
The Anatomical Record, EarlyView.Abstract The green iguana (Iguana iguana) is an iguanine lizard with herbivorous and arboreal habits, whose distribution spans through South America, Central America to the south of North America. Although the genus Iguana is well‐known, the species still lacks a comprehensive and up‐to‐date anatomical study, particularly addressing the axial skeleton,
Vieno Rosa +2 more
wiley +1 more source
Arthritis Research & TherapyObjective To explore IL11 co-expression profiles in our previously reported RNA-sequencing dataset of OA articular cartilage, in interaction with IL6, and to investigate the effects of hrIL11 administration as potential therapeutic strategy for OA ...
Margo Tuerlings +8 more
doaj +1 more source
Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis
Arthritis &Rheumatology, Accepted Article.Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm +2 more
wiley +1 more source
Mechanical effects of the intraarticular administration of high molecular weight hyaluronic acid plus phospholipid on synovial joint lubrication and prevention of articular cartilage degeneration in experimental osteoarthritis [PDF]
, 2003 Tsutomu Kawano +6 more
openalex +1 more source
Functional roles of COMP and TSP-4 in articular cartilage and their relevance in osteoarthritis [PDF]
, 2021 Kathrin Maly
openalex +1 more source
Arthritis &Rheumatology, EarlyView.Objective Anticitrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among patients with RA, including for motif‐containing epitopes in important self‐antigens like ...
S. Janna Bashar +4 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective The spontaneous K/BxN mouse model of rheumatoid arthritis has been used extensively to study chronic inflammation, contribution of immune cells, and the primordial role of autoreactive antibodies in disease initiation and severity. Only the ubiquitous enzyme glucose‐6‐phosphate isomerase (GPI) is the target of IgG autoantibodies secreted by ...
Thibault Vanhoucke +8 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin +15 more
wiley +1 more source