Results 131 to 140 of about 441,477 (379)

Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis

Arthritis Research & Therapy, 2014
IntroductionRecent studies have revealed that rapamycin activates autophagy in human chondrocytes preventing the development of osteoarthritis (OA) like changes in vitro, while the systemic injection of rapamycin reduces the severity of experimental ...
K. Takayama, Y. Kawakami, Makoto Kobayashi, N. Greco, J. Cummins, T. Matsushita, R. Kuroda, M. Kurosaka, Freddie H. Fu, J. Huard   +9 more
semanticscholar   +1 more source

O-alg-THAM/gel hydrogels functionalized with engineered microspheres based on mesenchymal stem cell secretion recruit endogenous stem cells for cartilage repair

Bioactive Materials, 2023
Lacking self-repair abilities, injuries to articular cartilage can lead to cartilage degeneration and ultimately result in osteoarthritis. Tissue engineering based on functional bioactive scaffolds are emerging as promising approaches for articular ...
Yucong Li, Linlong Li, Ming Wang, Boguang Yang, Baozhen Huang, Shanshan Bai, Xiaoting Zhang, Nan Hou, Haixing Wang, Zhengmeng Yang, Chong Tang, Ye Li, Wayne Yuk-Wai Lee, Lu Feng, Micky D. Tortorella, Gang Li   +15 more
doaj  

Bony island within the articular cartilage of the knee in a child: a rare condition for early osteoarthritis

Orthopedic Reviews, 2011
Articular cartilage is a specific type of connective tissue composed of hydrated proteoglycans within a matrix of collagen fibrils. In the elderly population, it shows degenerative changes that may results in osteoarthritis.
Taku Hatta, Takehiko Sugita, Toshimi Aizawa, Masahiro Ohnuma, Atsushi Takahashi, Eiji Itoi   +5 more
doaj   +1 more source

The Contact Between the Articular Cartilage and the Medullary Cavities of the Bone [PDF]

, 1950
D. E. Holmdahl, Bo E. Ingelmark
openalex   +1 more source

Enzyme systems in articular cartilage [PDF]

, 1940
Cecilia Lutwak‐Mann
openalex   +1 more source

Articular cartilage regeneration by activated skeletal stem cells

Nature Network Boston, 2020
M. Murphy, Lauren S. Koepke, Michael Lopez, Xinming Tong, Thomas H. Ambrosi, G. Gulati, O. Marecic, Yuting Wang, R. C. Ransom, Malachia Y. Hoover, Holly M. Steininger, Liming Zhao, Marcin P. Walkiewicz, N. Quarto, B. Levi, D. Wan, I. Weissman, S. Goodman, Fan Yang, M. Longaker, Charles K. F. Chan   +20 more
semanticscholar   +1 more source

Mesenchymal stem cells in the treatment of traumatic articular cartilage defects: a comprehensive review

Arthritis Research & Therapy, 2014
Articular cartilage has a limited capacity to repair following injury. Early intervention is required to prevent progression of focal traumatic chondral and osteochondral defects to advanced cartilage degeneration and osteoarthritis.
Troy D. Bornes, A. Adesida, N. Jomha
semanticscholar   +1 more source

A CASE OF LOOSE BODY IN THE KNEE-JOINT, FORMED BY THE DETACHMENT OF A PIECE OF THE ARTICULAR CARTILAGE BY AN INJURY. REMOVAL; RECOVERY [PDF]

, 1889
W JACOBSON
openalex   +1 more source

Dosage‐dependent effects of FGFR2W290R mutation on craniofacial shape and cellular dynamics of the basicranial synchondroses

The Anatomical Record, EarlyView.
Abstract Craniosynostosis is a common yet complex birth defect, characterized by premature fusion of the cranial sutures that can be syndromic or nonsyndromic. With over 180 syndromic associations, reaching genetic diagnoses and understanding variations in underlying cellular mechanisms remains a challenge.
Heather A. Richbourg, Marta Vidal‐García, Katherine A. Brakora, Jay Devine, Risa Takenaka, Nathan M. Young, Siew‐Ging Gong, Amanda Neves, Benedikt Hallgrímsson, Ralph S. Marcucio   +9 more
wiley   +1 more source

New perspectives for articular cartilage repair treatment through tissue engineering: A contemporary review.

World Journal of Orthopaedics, 2014
In this paper review we describe benefits and disadvantages of the established methods of cartilage regeneration that seem to have a better long-term effectiveness.
G. Musumeci, P. Castrogiovanni, R. Leonardi, F. Trovato, M. Szychlinska, A. D. Di Giunta, C. Loreto, S. Castorina   +7 more
semanticscholar   +1 more source