Results 131 to 140 of about 447,945 (376)

BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration

open access: yesAdvanced Science, EarlyView.
A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou   +8 more
wiley   +1 more source

O-alg-THAM/gel hydrogels functionalized with engineered microspheres based on mesenchymal stem cell secretion recruit endogenous stem cells for cartilage repair

open access: yesBioactive Materials, 2023
Lacking self-repair abilities, injuries to articular cartilage can lead to cartilage degeneration and ultimately result in osteoarthritis. Tissue engineering based on functional bioactive scaffolds are emerging as promising approaches for articular ...
Yucong Li   +15 more
doaj  

Bony island within the articular cartilage of the knee in a child: a rare condition for early osteoarthritis

open access: yesOrthopedic Reviews, 2011
Articular cartilage is a specific type of connective tissue composed of hydrated proteoglycans within a matrix of collagen fibrils. In the elderly population, it shows degenerative changes that may results in osteoarthritis.
Taku Hatta   +5 more
doaj   +1 more source

Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritis

open access: yesArthritis Research & Therapy, 2014
IntroductionRecent studies have revealed that rapamycin activates autophagy in human chondrocytes preventing the development of osteoarthritis (OA) like changes in vitro, while the systemic injection of rapamycin reduces the severity of experimental ...
K. Takayama   +9 more
semanticscholar   +1 more source

Advances in Medical Devices for Augmented Acupuncture Therapy

open access: yesAdvanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai   +7 more
wiley   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du   +7 more
wiley   +1 more source

Articular cartilage regeneration by activated skeletal stem cells

open access: yesNature Network Boston, 2020
M. Murphy   +20 more
semanticscholar   +1 more source

New perspectives for articular cartilage repair treatment through tissue engineering: A contemporary review.

open access: yesWorld Journal of Orthopaedics, 2014
In this paper review we describe benefits and disadvantages of the established methods of cartilage regeneration that seem to have a better long-term effectiveness.
G. Musumeci   +7 more
semanticscholar   +1 more source

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