Results 141 to 150 of about 173,109 (331)

LOXL2 in anabolic response to chondrodysplasia mice progressive TMJ and knee osteoarthritis [PDF]

, 2019
Osteoarthritis (OA) is a degenerative joint disease that affects an estimated 9.6 % of men and 18 % of women over 60 years of age. However, there is no chondroprotective agent that is approved for clinical application.
Alsaqer, Saqer
core  

Microgels for 3D Biofabrication

Aggregate, EarlyView.
This review highlights microgels as a versatile platform advancing biomanufacturing and tissue regeneration. It details their fabrication methods, core functions (bioprinting inks, suspension support baths, porous sacrificial scaffolds), and pivotal applications (drug delivery, dynamic cell culture microenvironments, tissue engineering scaffolds ...
Ting Xie, Huaibin Wang, Jieting Li, Leyan Xuan, Farzana Nazir, Long Chen, Zeyu Luo, Mian Wang, Yingling Miao, Dongyang Zhang, Wanlu Li, Guosheng Tang   +11 more
wiley   +1 more source

Behaviour of synovial fluid on surfaces of articular cartilage. A scanning electron microscope study. [PDF]

, 1969
Peter S. Walker, J. Sikorski, D. Dowson, M. D. Longfield, V Wright, T.F. Buckley   +5 more
openalex   +1 more source

Further Evidence That Chondrocalcinosis 1 (CCAL1) is a Confirmed Mendelian Phenotype With a Known Molecular Basis

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa, Mareike Selig, Markus Wingendorf, Matthew A. Brown, Oliver Bartsch   +4 more
wiley   +1 more source

New role of calcium‐binding fluorescent dye alizarin complexone in detecting permeability from articular cartilage to subchondral bone

FASEB BioAdvances
Osteoarthritis (OA) is a chronic degenerative joint disorder characterized by the progressive deterioration of articular cartilage and concomitant alterations in subchondral bone architecture. However, the precise mechanisms underlying the initiation and
Mingshu Cui, Mengcun Chen, Yanmei Yang, Hamza Akel, Bin Wang   +4 more
doaj   +1 more source

circNR3C2 promotes chondrogenic differentiation and cartilage repair of human adipose‐derived stem cells via the hsa‐miR‐647/SOX9 pathway

Animal Models and Experimental Medicine, EarlyView.
The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou, Huajun Wang, Hao Guo, Dongbin Luo, Xiaofei Zheng, Simin Luo   +5 more
wiley   +1 more source

Immunofluorescent Studies of Human Articular Cartilage [PDF]

, 1966
Peter Barland, Rosamond Janis, John Sandson   +2 more
openalex   +1 more source

Time‐ and dose‐related pathological changes in knee osteoarthritis rat model induced by monosodium iodoacetate

Animal Models and Experimental Medicine, EarlyView.
Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu, Qi Liu, Shuyan Xue, Siyuan Li, Nan Nan, Yang Liu, Huiqin Hao   +6 more
wiley   +1 more source

Sulphate (35SO4) Fixation by Human Articular Cartilage compared in the Knee and Shoulder Joints [PDF]

, 1961
D. H. Collins, G. Meachim
openalex   +1 more source

Systematic review of the subcutaneous air pouch model using monosodium urate and calcium pyrophosphate and recommendations for studying crystal‐related arthropathies

Animal Models and Experimental Medicine, EarlyView.
Simplified schematic for generation of the subcutaneous air pouch model in the rodent. On day 0 and 4, air is injected into the subcutaneous space on the dorsal surface of the rodent to generate a cavity analogous to a synovial joint. On day 6, monosodium urate (MSU) or calcium pyrophosphate (CPP) crystals are injected into the pouch to stimulate ...
Wenu Hewage, Josif Vidimce, Ryan G. Shiels, Michael Morgan, Andrew C. Bulmer   +4 more
wiley   +1 more source