Results 261 to 270 of about 447,945 (376)

RNA Binding Protein YTHDF2 Inhibits Synovial Fibroblast Inflammation and Bone Injury in Rheumatoid Arthritis by Reducing the mRNA Stability of IL‐6R

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study examined YTHDF2's role in modulating IL‐6R signaling to regulate synovial fibroblast inflammation and bone damage in rheumatoid arthritis (RA). Synovial tissues of RA patients were collected. Human fibroblast‐like synoviocyte (FLS), MH7A cell line, was induced with TNF‐α and transfected. Cell proliferation was assessed using MTT and
Yan Zhang   +9 more
wiley   +1 more source

Design and Evaluation of a Crosslinked Chitosan-Based Scaffold Containing Hyaluronic Acid for Articular Cartilage Reconstruction. [PDF]

open access: yesMolecules
Hamidi S   +8 more
europepmc   +1 more source

Circ_0006646 Promotes the Progression of Osteoarthritis via Upregulating CDH11 Expression in an IGF2BP2‐Dependent Manner

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative osteoarthropathy with an unclear pathogenesis. Circular RNA (circRNA) has been reported to be associated with OA progression. This study aims to explore the role and potential mechanism of hsa_circ_0006646 in OA. Interleukin‐1β (IL‐1β)‐induced human chondrocytes were used as the cell model of OA. RT‐
Ming‐Yu Hua   +3 more
wiley   +1 more source

Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation

open access: yesDevelopment, 2015
Ayan Ray   +4 more
semanticscholar   +1 more source

Thin flap sulcus‐deepening trochleoplasty in patellar instability yields good functional outcomes without progressive cartilage deterioration in the short‐term follow‐up—A retrospective single‐surgeon cohort study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Thin‐flap sulcus‐deepening trochleoplasty with medial patellofemoral ligament reconstruction is a safe and effective procedure in patellar instability and high‐grade trochlear dysplasia, with no cartilage deterioration after 34.8 ± 20.9 months. Abstract Purpose Sulcus‐deepening trochleoplasty (TP) effectively treats patellofemoral (PF) instability (PFI)
Jannik Frings   +6 more
wiley   +1 more source

Tissue growth as a mechanism for collagen fiber alignment in articular cartilage. [PDF]

open access: yesSci Rep
Peters JR   +5 more
europepmc   +1 more source

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